ES8401947A1 - Procedimiento para la preparacion de (-)-2-1-(2,6-diclorofenoxi)-etil-1,3-diazaciclopent-2-eno. - Google Patents

Procedimiento para la preparacion de (-)-2-1-(2,6-diclorofenoxi)-etil-1,3-diazaciclopent-2-eno.

Info

Publication number
ES8401947A1
ES8401947A1 ES518033A ES518033A ES8401947A1 ES 8401947 A1 ES8401947 A1 ES 8401947A1 ES 518033 A ES518033 A ES 518033A ES 518033 A ES518033 A ES 518033A ES 8401947 A1 ES8401947 A1 ES 8401947A1
Authority
ES
Spain
Prior art keywords
diazacyclopent
dichlorophenoxy
ene
ethyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518033A
Other languages
English (en)
Spanish (es)
Other versions
ES518033A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Natterman und Cie GmbH
Original Assignee
A Natterman und Cie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A Natterman und Cie GmbH filed Critical A Natterman und Cie GmbH
Publication of ES518033A0 publication Critical patent/ES518033A0/es
Publication of ES8401947A1 publication Critical patent/ES8401947A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
ES518033A 1981-12-10 1982-12-09 Procedimiento para la preparacion de (-)-2-1-(2,6-diclorofenoxi)-etil-1,3-diazaciclopent-2-eno. Expired ES8401947A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813149009 DE3149009A1 (de) 1981-12-10 1981-12-10 (-)-2-(1-(2,6-dichlorphenoxy)-ethyl)-1,3-diazacyclopent-2-en, dessen herstellung und seine verwendung in pharmazeutischen praeparaten

Publications (2)

Publication Number Publication Date
ES518033A0 ES518033A0 (es) 1984-01-01
ES8401947A1 true ES8401947A1 (es) 1984-01-01

Family

ID=6148418

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518033A Expired ES8401947A1 (es) 1981-12-10 1982-12-09 Procedimiento para la preparacion de (-)-2-1-(2,6-diclorofenoxi)-etil-1,3-diazaciclopent-2-eno.

Country Status (19)

Country Link
US (1) US4518783A (enExample)
EP (1) EP0081748B1 (enExample)
JP (1) JPS58105968A (enExample)
AR (1) AR242192A1 (enExample)
AT (1) ATE25520T1 (enExample)
AU (1) AU553892B2 (enExample)
CA (1) CA1176641A (enExample)
DD (1) DD205682A5 (enExample)
DE (2) DE3149009A1 (enExample)
DK (1) DK548182A (enExample)
ES (1) ES8401947A1 (enExample)
FI (1) FI73980C (enExample)
GR (1) GR77767B (enExample)
IE (1) IE54222B1 (enExample)
NO (1) NO158016C (enExample)
PT (1) PT75961B (enExample)
SU (1) SU1241989A3 (enExample)
YU (1) YU273682A (enExample)
ZA (1) ZA828743B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3407509A1 (de) 1984-03-01 1985-09-05 A. Nattermann & Cie GmbH, 5000 Köln Neue arzneimittelkombination zur behandlung von bluthochdruck und thromboembolischen erkrankungen
US4801617A (en) * 1987-04-06 1989-01-31 Leclerc Gerard Iminoimidazolidines useful in lowering intraocular pressure
FR2642422A1 (fr) * 1988-12-22 1990-08-03 Roussel Uclaf Nouvelles polyamines acylees, leur procede de preparation et leur application comme fongicides
JP2011530504A (ja) * 2008-08-08 2011-12-22 アジーン リミテッド ライアビリティー カンパニー Ｃｎｓ疾患及び病理の治療に用いるロフェキシジンエナンチオマー、並びにそのキラル合成法
US8101779B2 (en) * 2008-10-06 2012-01-24 University Of Kentucky Research Foundation Enantioselective synthesis of (+) and (–)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene
IT201900009777A1 (it) 2019-06-21 2020-12-21 Procos Spa Processo per la sintesi di lofexidina
ES2993182T3 (en) 2020-04-17 2024-12-23 Medichem Sa Process for the synthesis of lofexidine
CN111393369B (zh) * 2020-05-13 2022-12-16 宁夏大学 一种2-己基咪唑的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966757A (en) * 1967-02-23 1976-06-29 A. Nattermann & Cie Gmbh Imidazoline derivatives and processes for the production thereof
DE1695555A1 (de) * 1967-02-23 1970-07-16 Nordmark Werke Gmbh Neue Aryloxy-isoalkyl-delta2-imidazoline und deren Saeureadditionssalze sowie Verfahren zu ihrer Herstellung
US4025639A (en) * 1967-02-23 1977-05-24 A. Nattermann & Cie Gmbh Blood pressure lowering in human mammals
AU3546478A (en) * 1977-04-29 1979-11-01 Ciba Geigy Ag Ectoparasiticides

Also Published As

Publication number Publication date
IE54222B1 (en) 1989-07-19
SU1241989A3 (ru) 1986-06-30
ES518033A0 (es) 1984-01-01
FI73980B (fi) 1987-08-31
EP0081748A3 (en) 1984-03-07
IE822812L (en) 1983-06-10
ZA828743B (en) 1983-09-28
FI73980C (fi) 1987-12-10
ATE25520T1 (de) 1987-03-15
NO158016B (no) 1988-03-21
FI824216A0 (fi) 1982-12-08
NO158016C (no) 1988-06-29
DE3275466D1 (en) 1987-04-02
NO824148L (no) 1983-06-13
DK548182A (da) 1983-06-11
AU9105982A (en) 1983-06-16
GR77767B (enExample) 1984-09-25
US4518783A (en) 1985-05-21
PT75961B (en) 1985-10-04
CA1176641A (en) 1984-10-23
YU273682A (en) 1985-04-30
EP0081748B1 (de) 1987-02-25
AR242192A1 (es) 1993-03-31
AU553892B2 (en) 1986-07-31
FI824216L (fi) 1983-06-11
PT75961A (en) 1983-01-01
JPS58105968A (ja) 1983-06-24
DD205682A5 (de) 1984-01-04
EP0081748A2 (de) 1983-06-22
DE3149009A1 (de) 1983-06-23

Similar Documents

Publication Publication Date Title
IL67172A (en) Derivatives of cis,endo-2-azabicyclo-(3.3.0)-octane-3-carboxylic acid,process for their preparation and pharmaceutical agents containing these compounds
PT78816A (en) Process for preparing 1,2,4-triazol-3-one antidepressants and of pharmaceutical compositions containing the same
ZA828744B (en) (+)-2-(1-(2,6-dichlorophenoxy)-ethyl)-1,3-diazacyclopent-2-ene, the production thereof and the use in pharmaceutical preparations
GR3018685T3 (en) Method for the manufacture of a controlled release solid unit dosage form.
ES8401947A1 (es) Procedimiento para la preparacion de (-)-2-1-(2,6-diclorofenoxi)-etil-1,3-diazaciclopent-2-eno.
FI872255A0 (fi) Menetelmä uusien, farmaseuttisesti aktiivisten 1-(hydroksistyryyli)-5H-2,3-bentsodiatsepiinijohdannaisten valmistamiseksi
ZA828085B (en) Derivatives of cis,endo-2-azabicyclo-(3.3.0)-octane-3-carboxylic acid,a process for their preparation,agents containing these compounds and their use
DE3566079D1 (en) Pharmaceutical product for the treatment of hypertension and thromboembolic diseases
MY101747A (en) Dihydroorotic acids derivative, processes for preparing the same
DE3266439D1 (en) Process for the preparation of 1,3-disubstituted-2-oxo-4,5-imidazolinedicarboxylic acid
IT1190817B (it) Procedimento per la produzione di aminoderivati 1-posizione,di 1-(3'-4-metilendiossifenil)propano-2-olo
DE3264854D1 (en) Process for the preparation of condensed 1,2,3-triazoles
EP0093497A3 (en) Anthelmintic treatment
YU107779A (en) Process for preparing derivatives of benzoylphenoxyalkanoic acid, which normalize the blood lipide level
PL248314A1 (en) Process for preparing derivatives of bicyclo/3,2,1/-octano-3-carboxylic acid
DE3261303D1 (en) Process for the preparation of 4,4'-dibenzoylamino dianthrimide carbazole
IT1190818B (it) Procedimento per la produzione di alfa-aminoderivati ciclici di 1-(3',4'-metilendiossifenil)etanolo
AU586557B2 (en) 1,4-dihydropyridine derivatives, process for their preparation and medicaments containing these compounds
ES8403458A1 (es) "un procedimiento para la preparacion de nuevos derivados de tetrahidroquinolina".
PH19644A (en) Process for the preparation of 4(3-methyl-2-butenyl)-1,2-diphenyl-3,5-dioxo-pyrazolidine
PT74540A (en) Process for preparing acid addition salts of 3,4-diacyloxy-al- pha-<(methylamino)-methyl>-benzylalcohol
DE3460020D1 (en) Process for the preparation of the disodium salt of 1,5-naphthalenedisulphonic acid
HRP930368B1 (en) Process for the preparation of 2-(2,4-difluorophenyl)-1,3-bis-(1h-1,2,4-triazole-1-il)-propan-2-oles
HRP930651B1 (en) Process for the preparation of 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyl-quinoline-3-carboxylic acid derivative
HUT46893A (en) Process for production of optically clean 5-/-/-1-prophil-2-6'-pipecoloxilidid-hydrochlorid

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301