ES8308072A1 - Procedimiento de bioanalisis para determinar una sustancia bioactiva en una muestra. - Google Patents

Procedimiento de bioanalisis para determinar una sustancia bioactiva en una muestra.

Info

Publication number
ES8308072A1
ES8308072A1 ES513257A ES513257A ES8308072A1 ES 8308072 A1 ES8308072 A1 ES 8308072A1 ES 513257 A ES513257 A ES 513257A ES 513257 A ES513257 A ES 513257A ES 8308072 A1 ES8308072 A1 ES 8308072A1
Authority
ES
Spain
Prior art keywords
determining
analyte
bioactive substances
molecule
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513257A
Other languages
English (en)
Other versions
ES513257A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Battelle Memorial Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute Inc filed Critical Battelle Memorial Institute Inc
Publication of ES8308072A1 publication Critical patent/ES8308072A1/es
Publication of ES513257A0 publication Critical patent/ES513257A0/es
Granted legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21Polarisation-affecting properties
    • G01N21/211Ellipsometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property

Abstract

DISPOSITIVO DE BIOANALISIS PARA DETERMINAR UNA SUBSTANCIA BIOACTIVA EN UNA MUESTRA. CONSTA DE UNA FUENTE LUMINOSA (1), UN CORTADOR (2) QUE INTERRUMPE PERIODICAMENTE UNA SEÑAL, UN POLARIZADOR (3), UN ELEMENTO DE MUESTRA (4), UN COMPENSADOR (6), UN ANALIZADOR (7), UN DETECTOR DE LUZ (8) QUE CONVIERTE LA SEÑAL LUMINOSA EN SEÑAL ELECTRICA Y QUE ALIMENTA UN AMPLIFICADOR SINCRONIZADO (9). EXISTE TAMBIEN UN MICROPROCESADOR (11) PARA PROCESADO DE SEÑAL Y UN REGISTRADOR (10) CONECTADO AL AMPLIFICADOR (9).
ES513257A 1981-06-22 1982-06-18 Procedimiento de bioanalisis para determinar una sustancia bioactiva en una muestra. Granted ES513257A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP81810255A EP0067921B1 (en) 1981-06-22 1981-06-22 A method for determining bioactive substances

Publications (2)

Publication Number Publication Date
ES8308072A1 true ES8308072A1 (es) 1983-08-01
ES513257A0 ES513257A0 (es) 1983-08-01

Family

ID=8188668

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513257A Granted ES513257A0 (es) 1981-06-22 1982-06-18 Procedimiento de bioanalisis para determinar una sustancia bioactiva en una muestra.

Country Status (8)

Country Link
US (1) US4508832A (es)
EP (1) EP0067921B1 (es)
JP (1) JPS5824861A (es)
AT (1) ATE30780T1 (es)
AU (1) AU551446B2 (es)
CA (1) CA1203163A (es)
DE (1) DE3176524D1 (es)
ES (1) ES513257A0 (es)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4592894A (en) * 1983-11-22 1986-06-03 The United States Of America As Represented By The United States Department Of Energy Field emission chemical sensor for receptor/binder, such as antigen/antibody
US5500188A (en) * 1984-03-01 1996-03-19 Molecular Devices Corporation Device for photoresponsive detection and discrimination
US4647544A (en) * 1984-06-25 1987-03-03 Nicoli David F Immunoassay using optical interference detection
AU581917B2 (en) * 1984-09-25 1989-03-09 Richard Distl Dual-beam real-time polarimeter
DE3506703C1 (de) * 1985-02-26 1986-04-30 Sagax Instrument AB, Sundbyberg Verfahren zur Sequenzanalyse von Nucleinsaeuren,insbesondere der Desoxyribonucleinsaeure (DNA) und der Ribonucleinsaeure (RNA),sowie Traeger zur Durchfuehrung des Verfahrens und Verfahren zur Herstellung des Traegers
US6060237A (en) * 1985-02-26 2000-05-09 Biostar, Inc. Devices and methods for optical detection of nucleic acid hybridization
JPS6283641A (ja) * 1985-10-08 1987-04-17 Sharp Corp 電界効果型半導体センサ
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US5482830A (en) * 1986-02-25 1996-01-09 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
GB8612221D0 (en) * 1986-05-20 1986-06-25 Amersham Int Plc Assaying species in sample
JPS6316246A (ja) * 1986-07-08 1988-01-23 Hamamatsu Photonics Kk 旋光度変化測定装置
CA1317206C (en) * 1986-09-22 1993-05-04 Takeyuki Kawaguchi Method for detecting a component of a biological system and detection device and kit therefor
US4908508A (en) * 1987-02-12 1990-03-13 Akzo N.V. Process and apparatus for determining thicknesses of layers
US5079155A (en) * 1987-03-02 1992-01-07 E. I. Du Pont De Nemours And Company Fluorocarbon polymer support for chromatographic separations, diagnostic assays and enzyme immobilization
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
SE462408B (sv) * 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
US5639671A (en) * 1989-09-18 1997-06-17 Biostar, Inc. Methods for optimizing of an optical assay device
US5541057A (en) * 1989-09-18 1996-07-30 Biostar, Inc. Methods for detection of an analyte
IL96483A (en) * 1990-11-27 1995-07-31 Orbotech Ltd Optical inspection method and apparatus
EP0525178B1 (en) * 1991-02-11 1998-11-25 Biostar, Inc. Elements and methods employing polymeric surface amplification agents
DE69232692T2 (de) * 1991-02-11 2002-11-21 Thermo Biostar Inc Ellipsometrisches immuntestsystem und -methode mit einer dünnschicht-nachweisvorrichtung
US5550063A (en) * 1991-02-11 1996-08-27 Biostar, Inc. Methods for production of an optical assay device
US5955377A (en) * 1991-02-11 1999-09-21 Biostar, Inc. Methods and kits for the amplification of thin film based assays
IE921050A1 (en) * 1991-04-02 1992-10-07 Biotech Australia Pty Ltd Oral delivery systems for microparticles
US5418136A (en) * 1991-10-01 1995-05-23 Biostar, Inc. Devices for detection of an analyte based upon light interference
DE4200088C2 (de) * 1992-01-04 1997-06-19 Nahm Werner Verfahren und Vorrichtung zum optischen Nachweis einer An- oder Einlagerung mindestens einer stofflichen Spezies in oder an mindestens einer dünnen Schicht
EP0746769B1 (en) * 1992-03-27 2006-09-06 Abbott Laboratories Automated continuous and random access analytical method
US5605665A (en) * 1992-03-27 1997-02-25 Abbott Laboratories Reaction vessel
EP1635162A3 (en) * 1992-07-31 2010-02-24 Inverness Medical - BioStar Inc. Devices and methods for detection of an analyte based upon light interference
US5494829A (en) * 1992-07-31 1996-02-27 Biostar, Inc. Devices and methods for detection of an analyte based upon light interference
US5706212A (en) * 1996-03-20 1998-01-06 Board Of Regents Of University Of Nebraska Infrared ellipsometer/polarimeter system, method of calibration, and use thereof
US5552272A (en) * 1993-06-10 1996-09-03 Biostar, Inc. Detection of an analyte by fluorescence using a thin film optical device
US5413939A (en) * 1993-06-29 1995-05-09 First Medical, Inc. Solid-phase binding assay system for interferometrically measuring analytes bound to an active receptor
DE19629243A1 (de) * 1996-07-19 1998-01-29 Udo Dr Ris Verfahren zur quantitativen und/oder qualitativen Bestimmung von Atomen oder Molekülen
US5958704A (en) 1997-03-12 1999-09-28 Ddx, Inc. Sensing system for specific substance and molecule detection
IL139631A0 (en) * 1998-05-13 2002-02-10 Ddx Inc Enumeration method of analyte detection
DE19900119C2 (de) * 1999-01-06 2001-02-22 Horst Messer Verfahren und Vorrichtung zur Diagnose allergischer Symptome
DE10006083B4 (de) 2000-02-11 2004-01-22 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Verfahren zur quantitativen und/oder qualitativen Bestimmung von Schichtdicken sowie ein Mikroreaktionsgefäß und eine Titerplatte
US7023547B2 (en) * 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
US7126688B2 (en) * 2000-07-11 2006-10-24 Maven Technologies, Llc Microarray scanning
US6594011B1 (en) 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US6833920B2 (en) 2000-07-11 2004-12-21 Maven Technologies Llc Apparatus and method for imaging
US7518724B2 (en) * 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US6934024B2 (en) * 2000-10-18 2005-08-23 Regents Of The University Of Minnesota Ellipsometry methods and apparatus using solid immersion tunneling
AU2002249994A1 (en) * 2001-04-19 2002-11-05 Maven Technologies Llc. Imaging apparatus and method
DE10126152C2 (de) * 2001-05-30 2003-12-24 Inst Mikrotechnik Mainz Gmbh Ortsaufgelöstes Ellipsometrie-Verfahren zur quantitativen und/oder qualitativen Bestimmung von Probenänderungen, Biochip und Meßanordnung
US7064828B1 (en) * 2001-12-19 2006-06-20 Nanometrics Incorporated Pulsed spectroscopy with spatially variable polarization modulation element
US7470518B2 (en) 2002-02-12 2008-12-30 Cellectricon Ab Systems and method for rapidly changing the solution environment around sensors
EP1476536B1 (en) 2002-02-12 2011-07-20 Cellectricon Ab Systems and methods for rapidly changing the solution environment around sensors
GB0209329D0 (en) * 2002-04-24 2002-06-05 Imp College Innovations Ltd A device
US20030224370A1 (en) * 2002-05-31 2003-12-04 William Rassman Method and apparatus for recognizing molecular compounds
JP2007528692A (ja) * 2003-05-28 2007-10-18 メイバン・テクノロジーズ・エルエルシー 分子化合物を認識する方法及び装置
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
CA2956645A1 (en) 2003-07-12 2005-03-31 David A. Goldberg Sensitive and rapid biodetection
US7341841B2 (en) * 2003-07-12 2008-03-11 Accelr8 Technology Corporation Rapid microbial detection and antimicrobial susceptibility testing
US20060034943A1 (en) * 2003-10-31 2006-02-16 Technology Innovations Llc Process for treating a biological organism
US7838285B1 (en) 2006-04-24 2010-11-23 Maven Biotechnologies LLC Imaging electrophoresis system
WO2007135689A2 (en) 2006-05-24 2007-11-29 Ben Gurion University Of The Negev R&D Authority Membranes, coatings and films and methods for their preparation
US7867783B2 (en) 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
FR2923477B1 (fr) * 2007-11-12 2011-03-18 Inst Francais Du Petrole Solide cristallise im-18 et son procede de preparation
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
WO2010095139A1 (en) 2009-02-19 2010-08-26 Ben-Gurion University Of The Negev Research And Development Authority Chemically resistant membranes, coatings and films and methods for their preparation
US9475049B2 (en) 2009-07-31 2016-10-25 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analyte, and uses thereof
US8012770B2 (en) 2009-07-31 2011-09-06 Invisible Sentinel, Inc. Device for detection of antigens and uses thereof
CA2777061C (en) 2009-10-09 2018-06-19 Invisible Sentinel, Inc. Device for detection of analytes and uses thereof
KR101105328B1 (ko) * 2009-11-23 2012-01-16 한국표준과학연구원 분자 흡착 및 해리 동특성 측정장치 및 측정방법
US8355133B2 (en) 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
WO2012081026A2 (en) 2010-12-12 2012-06-21 Ben-Gurion University Of The Negev Research And Development Authority Anion exchange membranes, methods of preparation and uses
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
WO2012122314A2 (en) 2011-03-07 2012-09-13 Accelr8 Technology Corporation Rapid cell purification systems
NZ629703A (en) 2012-03-09 2016-05-27 Invisible Sentinel Inc Methods and compositions for detecting multiple analytes with a single signal
KR101383652B1 (ko) * 2012-10-15 2014-04-09 한국표준과학연구원 분자접합특성 및 완충용액 굴절률 동시 측정장치 및 측정방법
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
FR3015677B1 (fr) * 2013-12-23 2016-01-29 Commissariat Energie Atomique Procede et dispositif de preparation et d'analyse optique d'un echantillon solide soumis a un environnement controle, par spectrometrie infrarouge a reflexions internes multiples
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US10023895B2 (en) 2015-03-30 2018-07-17 Accelerate Diagnostics, Inc. Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing
CN106959274B (zh) * 2017-05-12 2023-06-06 燕山大学 一种基于布儒斯特定律的溶液浓度监测方法及装置
WO2019073519A1 (ja) * 2017-10-10 2019-04-18 三菱電機株式会社 半導体装置の試験方法、および半導体装置の製造方法
CN108254575B (zh) * 2018-01-16 2019-12-10 中国科学院力学研究所 一种适用于椭偏成像传感器的双抗体夹心检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2666355A (en) * 1951-10-12 1954-01-19 Hans J Trurnit Method of studying chemical reactions by measuring interfacial film thicknesses
CA1025772A (en) * 1972-06-26 1978-02-07 Ivar Giaever Method and apparatus for detection and purification of proteins and antibodies
GB1479661A (en) * 1972-06-26 1977-07-13 Gen Electric Method and apparatus for detection and purification of proteins and antibodies
US4054646A (en) * 1973-07-30 1977-10-18 General Electric Method and apparatus for detection of antibodies and antigens
CA1047918A (en) * 1973-07-30 1979-02-06 General Electric Company Method and apparatus for detection and purification of proteins and antibodies
US3979184A (en) * 1975-05-27 1976-09-07 General Electric Company Diagnostic device for visually detecting presence of biological particles
US4050895A (en) * 1975-09-26 1977-09-27 Monsanto Research Corporation Optical analytical device, waveguide and method

Also Published As

Publication number Publication date
EP0067921A1 (en) 1982-12-29
JPS5824861A (ja) 1983-02-14
AU551446B2 (en) 1986-05-01
ES513257A0 (es) 1983-08-01
DE3176524D1 (en) 1987-12-17
US4508832A (en) 1985-04-02
CA1203163A (en) 1986-04-15
AU8491082A (en) 1983-01-06
ATE30780T1 (de) 1987-11-15
EP0067921B1 (en) 1987-11-11

Similar Documents

Publication Publication Date Title
ES8308072A1 (es) Procedimiento de bioanalisis para determinar una sustancia bioactiva en una muestra.
US3873269A (en) Indicator for the determination of urea
TW369599B (en) A reagent strip and a method for measuring glucose concentration in a sample of whole blood
ES452054A1 (es) Metodo para el estudio de reacciones enzimaticas y otras reacciones bioquimicas.
EP0417305A4 (en) Analyzer of liquid sample and analyzing method of liquid sample using said analyzer
EP0960946A3 (en) Method and apparatus for the determination of analytes
EP0342447A3 (en) Direct measuring assay strip
FI102192B1 (fi) Menetelmä kokoveren glukoosipitoisuuden määrittämiseksi sekä menetelmän toteuttamiseen soveltuva kyvetti ja fotometri
JPS5592698A (en) Test strip for glucose determination
CA2018166A1 (en) Process for measuring body fluid components
SE7709357L (sv) Kontinuerlig koncentrationsbestemning
SE7706338L (sv) Sett och anordning for analysering
IE42572L (en) Process for enzymatic analysis
NO932916D0 (no) Fremgangsmaate for aa bestemme kapillartrykk-kurven i et poroest medium ved hjelp av eksperimentelle forsoek
JPS5697863A (en) Method and apparatus for analyzing amylase
ES469792A1 (es) Dispositivo para preparar un liquido de medicion para uso eninstrumentos analiticos opticos.
EP0161299A1 (en) Sensor for chemical analysis
JPS5347517A (en) Immobilized antibody membrane for antigen protein determinationmethod and its apparatus
JPS57154056A (en) Reagent for determining reduced type vitamin c and method for determining said vitamin c
JPS52113291A (en) Enzyme analysis
JPS5443796A (en) Enzyme electrode
JPS5461984A (en) Electrochemical measuring method of alcohol concentrations and electrode used for the same
JPS57211542A (en) Enzyme electrode
JPS56158098A (en) Measurement of alpha-amylase activity
JPS56150333A (en) Sample analysis method