ES8306151A1 - Procedimiento para preparar derivados de purina. - Google Patents

Procedimiento para preparar derivados de purina.

Info

Publication number
ES8306151A1
ES8306151A1 ES507102A ES507102A ES8306151A1 ES 8306151 A1 ES8306151 A1 ES 8306151A1 ES 507102 A ES507102 A ES 507102A ES 507102 A ES507102 A ES 507102A ES 8306151 A1 ES8306151 A1 ES 8306151A1
Authority
ES
Spain
Prior art keywords
purine derivatives
production
hydrogen
intermediates therefor
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507102A
Other languages
English (en)
Other versions
ES507102A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55161099A external-priority patent/JPS5785388A/ja
Priority claimed from JP12951881A external-priority patent/JPS5832867A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES507102A0 publication Critical patent/ES507102A0/es
Publication of ES8306151A1 publication Critical patent/ES8306151A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE PURINA, DE FORMULA GENERAL (I), EN LA QUE R Y R SON, CADA UNO DE ELLOS, HALOGENO; Y R ES ALCOHILO O ALILO, Y SUS SALES DE ADICION DE ACIDOS. COMPRENDE LAS SIGUIENTES FASES: PRIMERA, SE SOMETE A UNA REACCION DE REDUCCION UN COMPUESTO DE ARILAZOPIRIMIDINA DE FORMULA GENERAL (I), EN LA QUE R ES ARILO; Y R TIENE EL SIGNIFICADO YA INDICADO; SEGUNDA, EL PRODUCTO RESULTANTE SE HACE REACCIONAR CON ACIDO FORMICO EN PRESENCIA DE UN DERIVADO DEL ACIDO CARBOXILICO; Y POR ULTIMO, EL PRODUCTO RESULTANTE DE LA SEGUNDA FASE SE HACE REACCIONAR CON UN COMPUESTO DE FORMULA (III), EN LA QUE R Y R TIENEN EL SIGNIFICADO YA INDICADO; Y X ES HALOGENO, EN PRESENCIA DE UNA BASE. DE APLICACION COMO AGENTES CONTRA LOS COCCIDIOS.
ES507102A 1980-11-14 1981-11-13 Procedimiento para preparar derivados de purina. Expired ES8306151A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55161099A JPS5785388A (en) 1980-11-14 1980-11-14 Preparation of purine derivative
JP12951881A JPS5832867A (ja) 1981-08-18 1981-08-18 新規アリ−ルアゾピリミジン化合物

Publications (2)

Publication Number Publication Date
ES507102A0 ES507102A0 (es) 1983-05-01
ES8306151A1 true ES8306151A1 (es) 1983-05-01

Family

ID=26464872

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507102A Expired ES8306151A1 (es) 1980-11-14 1981-11-13 Procedimiento para preparar derivados de purina.

Country Status (7)

Country Link
US (1) US4423219A (es)
EP (1) EP0052959B1 (es)
BR (1) BR8107358A (es)
CA (1) CA1171081A (es)
DE (1) DE3173671D1 (es)
DK (1) DK503081A (es)
ES (1) ES8306151A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1377353A (zh) * 1999-04-02 2002-10-30 欧罗赛铁克股份有限公司 具有磷酸二酯酶iv抑制活性的嘌呤衍生物
CN103992322A (zh) * 2014-05-20 2014-08-20 安徽农业大学 一种抗球虫药物氟腺嘌呤的合成方法
CN107698589B (zh) * 2017-10-16 2019-06-07 浙江金伯士药业有限公司 一种阿德呋啉的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794270A (fr) * 1972-01-21 1973-07-19 Basf Ag Pigments organosolubles derives de la pyrimidine
US4092314A (en) * 1975-07-07 1978-05-30 Merck & Co., Inc. Preparation of 4,6-diamino-5-arylazopyrimidines and adenine compounds
DE2715984A1 (de) * 1977-04-09 1978-10-26 Basf Ag Farbstoffzubereitungen fuer cellulose und cellulosehaltiges textilmaterial
US4189485A (en) * 1977-08-23 1980-02-19 Takeda Chemical Industries, Ltd. Purine derivatives

Also Published As

Publication number Publication date
EP0052959B1 (en) 1986-01-29
DK503081A (da) 1982-05-15
US4423219A (en) 1983-12-27
BR8107358A (pt) 1982-08-03
ES507102A0 (es) 1983-05-01
DE3173671D1 (en) 1986-03-13
EP0052959A1 (en) 1982-06-02
CA1171081A (en) 1984-07-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201