ATE61329T1 - Verfahren zur herstellung von rooperol, hypoxosid und deren derivaten. - Google Patents
Verfahren zur herstellung von rooperol, hypoxosid und deren derivaten.Info
- Publication number
- ATE61329T1 ATE61329T1 AT86304715T AT86304715T ATE61329T1 AT E61329 T1 ATE61329 T1 AT E61329T1 AT 86304715 T AT86304715 T AT 86304715T AT 86304715 T AT86304715 T AT 86304715T AT E61329 T1 ATE61329 T1 AT E61329T1
- Authority
- AT
- Austria
- Prior art keywords
- phenyl group
- groups
- alkylenedioxy
- halide
- alkoxy
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- NKCXUXCXXINIMN-LITNSJRUSA-N (2S,3R,4S,5S,6R)-2-[2-hydroxy-4-[(E)-5-[3-hydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]pent-1-en-4-ynyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC(C(=C1)O)=CC=C1\C=C\CC#CC(C=C1O)=CC=C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 NKCXUXCXXINIMN-LITNSJRUSA-N 0.000 title 1
- JQPOMMNEABQHEU-DUXPYHPUSA-N 4-[(e)-5-(3,4-dihydroxyphenyl)pent-1-en-4-ynyl]benzene-1,2-diol Chemical compound C1=C(O)C(O)=CC=C1\C=C\CC#CC1=CC=C(O)C(O)=C1 JQPOMMNEABQHEU-DUXPYHPUSA-N 0.000 title 1
- NKCXUXCXXINIMN-UHFFFAOYSA-N hypoxoside Natural products OC1C(O)C(O)C(CO)OC1OC(C(=C1)O)=CC=C1C=CCC#CC(C=C1O)=CC=C1OC1C(O)C(O)C(O)C(CO)O1 NKCXUXCXXINIMN-UHFFFAOYSA-N 0.000 title 1
- JQPOMMNEABQHEU-UHFFFAOYSA-N rooperol Natural products C1=C(O)C(O)=CC=C1C=CCC#CC1=CC=C(O)C(O)=C1 JQPOMMNEABQHEU-UHFFFAOYSA-N 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 8
- 125000004423 acyloxy group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000004820 halides Chemical class 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000005389 trialkylsiloxy group Chemical group 0.000 abstract 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005210 alkyl ammonium group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/205—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings
- C07C39/21—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a non-condensed ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA854640 | 1985-06-19 | ||
| EP86304715A EP0206765B1 (de) | 1985-06-19 | 1986-06-19 | Verfahren zur Herstellung von Rooperol, Hypoxosid und deren Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE61329T1 true ATE61329T1 (de) | 1991-03-15 |
Family
ID=25577959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86304715T ATE61329T1 (de) | 1985-06-19 | 1986-06-19 | Verfahren zur herstellung von rooperol, hypoxosid und deren derivaten. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5008471A (de) |
| EP (1) | EP0206765B1 (de) |
| JP (1) | JPS6242942A (de) |
| AT (1) | ATE61329T1 (de) |
| DE (1) | DE3677830D1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4956502A (en) * | 1985-06-19 | 1990-09-11 | Rooperol (N.A.) Nv | Process for the preparation of rooperol derivative |
| EP0206765B1 (de) * | 1985-06-19 | 1991-03-06 | Rooperol (Na) Nv | Verfahren zur Herstellung von Rooperol, Hypoxosid und deren Derivaten |
| AU2300588A (en) * | 1987-08-04 | 1989-03-01 | Trustees Of Columbia University In The City Of New York, The | Caffeic acid esters and method of preparing and using same |
| MX9305453A (es) * | 1992-09-07 | 1994-05-31 | Virostat Na Nv | Metodo para tratar infecciones virales. |
| US5569649A (en) * | 1994-06-14 | 1996-10-29 | Phytopharm (Na) N.V. | Anti-inflammatory treatment method |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2120650A (en) * | 1982-04-19 | 1983-12-07 | Roecar Holdings Nv | Rooperol derivatives |
| GB8317850D0 (en) * | 1983-06-30 | 1983-08-03 | Roecar Holdings Nv | Rooperol and its derivatives |
| EP0206765B1 (de) * | 1985-06-19 | 1991-03-06 | Rooperol (Na) Nv | Verfahren zur Herstellung von Rooperol, Hypoxosid und deren Derivaten |
-
1986
- 1986-06-19 EP EP86304715A patent/EP0206765B1/de not_active Expired - Lifetime
- 1986-06-19 DE DE8686304715T patent/DE3677830D1/de not_active Expired - Fee Related
- 1986-06-19 JP JP61143994A patent/JPS6242942A/ja active Pending
- 1986-06-19 AT AT86304715T patent/ATE61329T1/de not_active IP Right Cessation
-
1989
- 1989-06-13 US US07/365,751 patent/US5008471A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6242942A (ja) | 1987-02-24 |
| DE3677830D1 (de) | 1991-04-11 |
| US5008471A (en) | 1991-04-16 |
| EP0206765B1 (de) | 1991-03-06 |
| EP0206765A3 (en) | 1987-08-26 |
| EP0206765A2 (de) | 1986-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |