ES8302679A1 - Procedimiento de preparacion de una 1-(trialcoxibencil)pi- perazina. - Google Patents
Procedimiento de preparacion de una 1-(trialcoxibencil)pi- perazina.Info
- Publication number
- ES8302679A1 ES8302679A1 ES506814A ES506814A ES8302679A1 ES 8302679 A1 ES8302679 A1 ES 8302679A1 ES 506814 A ES506814 A ES 506814A ES 506814 A ES506814 A ES 506814A ES 8302679 A1 ES8302679 A1 ES 8302679A1
- Authority
- ES
- Spain
- Prior art keywords
- trialkoxybenzyl
- piperazinone
- piperadine
- manufacture
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- IWELDVXSEVIIGI-UHFFFAOYSA-N piperazin-2-one Chemical compound O=C1CNCCN1 IWELDVXSEVIIGI-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 229910010084 LiAlH4 Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8023678A FR2493316A1 (fr) | 1980-11-06 | 1980-11-06 | Nouveau procede de preparation des (trialcoxy benzyl)-1 piperazines et notamment de la (trimethoxy-2', 3', 4' benzyl)-1 piperazine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES506814A0 ES506814A0 (es) | 1983-02-01 |
| ES8302679A1 true ES8302679A1 (es) | 1983-02-01 |
Family
ID=9247720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506814A Expired ES8302679A1 (es) | 1980-11-06 | 1981-11-03 | Procedimiento de preparacion de una 1-(trialcoxibencil)pi- perazina. |
Country Status (16)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH650176A5 (fr) * | 1982-08-23 | 1985-07-15 | Daussan & Co | Dispositif pour la coulee du metal fondu. |
| FR2661176B1 (fr) * | 1990-04-20 | 1992-06-12 | Adir | Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive. |
| FR2703048B1 (fr) * | 1993-03-24 | 1996-01-05 | Adir | Nouveaux composes n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
| CN100413854C (zh) * | 2004-06-29 | 2008-08-27 | 北京德众万全药物技术开发有限公司 | 一种曲美他嗪及其药用盐的制备方法 |
| CN102993122B (zh) * | 2012-12-24 | 2015-03-04 | 武汉武药制药有限公司 | 盐酸曲美他嗪的合成新路线 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2438725A1 (de) * | 1974-08-12 | 1976-02-26 | Knoll Ag | Piperazinderivate |
-
1980
- 1980-11-06 FR FR8023678A patent/FR2493316A1/fr active Granted
-
1981
- 1981-11-03 ES ES506814A patent/ES8302679A1/es not_active Expired
- 1981-11-03 MA MA19524A patent/MA19322A1/fr unknown
- 1981-11-04 CH CH7061/81A patent/CH651031A5/fr not_active IP Right Cessation
- 1981-11-04 IT IT49630/81A patent/IT1142928B/it active
- 1981-11-04 EG EG640/81A patent/EG15454A/xx active
- 1981-11-04 MX MX819743U patent/MX6973E/es unknown
- 1981-11-05 GR GR66443A patent/GR75036B/el unknown
- 1981-11-05 CA CA000389487A patent/CA1181069A/fr not_active Expired
- 1981-11-05 AU AU77121/81A patent/AU546225B2/en not_active Ceased
- 1981-11-05 LU LU83738A patent/LU83738A1/fr unknown
- 1981-11-05 PT PT73935A patent/PT73935B/pt unknown
- 1981-11-05 BE BE0/206459A patent/BE891012A/fr not_active IP Right Cessation
- 1981-11-06 JP JP56178238A patent/JPS57108086A/ja active Pending
- 1981-11-06 OA OA57535A patent/OA06939A/xx unknown
- 1981-11-06 DE DE19813144235 patent/DE3144235A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| LU83738A1 (fr) | 1982-06-30 |
| EG15454A (en) | 1985-12-31 |
| OA06939A (fr) | 1983-07-31 |
| MA19322A1 (fr) | 1982-07-01 |
| CA1181069A (fr) | 1985-01-15 |
| CH651031A5 (fr) | 1985-08-30 |
| PT73935A (fr) | 1981-12-01 |
| IT1142928B (it) | 1986-10-15 |
| AU7712181A (en) | 1982-05-13 |
| ES506814A0 (es) | 1983-02-01 |
| BE891012A (fr) | 1982-05-05 |
| FR2493316B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1983-04-15 |
| JPS57108086A (en) | 1982-07-05 |
| DE3144235A1 (de) | 1982-06-24 |
| GR75036B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-07-12 |
| AU546225B2 (en) | 1985-08-22 |
| PT73935B (fr) | 1983-11-30 |
| FR2493316A1 (fr) | 1982-05-07 |
| MX6973E (es) | 1987-01-13 |
| IT8149630A0 (it) | 1981-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |
Effective date: 19960401 |