ES8301277A1 - Un procedimiento para la preparacion de una nueva sustancia antibiotica sf-2103a. - Google Patents

Un procedimiento para la preparacion de una nueva sustancia antibiotica sf-2103a.

Info

Publication number
ES8301277A1
ES8301277A1 ES504813A ES504813A ES8301277A1 ES 8301277 A1 ES8301277 A1 ES 8301277A1 ES 504813 A ES504813 A ES 504813A ES 504813 A ES504813 A ES 504813A ES 8301277 A1 ES8301277 A1 ES 8301277A1
Authority
ES
Spain
Prior art keywords
substance
antibiotic
production
recovering
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504813A
Other languages
English (en)
Other versions
ES504813A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP11299680A external-priority patent/JPS5736989A/ja
Priority claimed from JP55157631A external-priority patent/JPS5781498A/ja
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Publication of ES504813A0 publication Critical patent/ES504813A0/es
Publication of ES8301277A1 publication Critical patent/ES8301277A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UNA SUSTANCIA ANTIBIOTICA SF-2103A Y DE SUS SALES, DE FORMULA (I). CONSISTE EN EL CULTIVO DE UNA CEPA PRODUCTORA DE LA SUSTANCIA SF-2103A, PERTENECIENTE AL GENERO STREPTOMYCES, EN UN MEDIO NUTRIENTE QUE CONTIENE FUENTES ASIMILABLES DE CARBONO Y NITROGENO, ASI COMO, OPCIONALMENTE, SALES INORGANICAS Y/O UN AGENTE DESESPUMANTE; EL CULTIVO SE LLEVA A CABO EN SUMERGIDO, EN CONDICIONES AIREADAS, A UNA TEMPERATURA ENTRE 20<025>C Y 35<025>C. SEGUIDO DE LA RECUPERACION DE LA SUSTANCIA OBTENIDA POR FILTRACION, CROMATOGRAFIA, EXTRACCION Y LIOFILIZACION.
ES504813A 1980-08-19 1981-08-18 Un procedimiento para la preparacion de una nueva sustancia antibiotica sf-2103a. Expired ES8301277A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11299680A JPS5736989A (ja) 1980-08-19 1980-08-19 Shinkoseibutsushitsusf 2103abutsushitsunoseizoho
JP55157631A JPS5781498A (en) 1980-11-11 1980-11-11 New antibiotic sf-2103a substance and its preparation

Publications (2)

Publication Number Publication Date
ES504813A0 ES504813A0 (es) 1982-12-01
ES8301277A1 true ES8301277A1 (es) 1982-12-01

Family

ID=26452026

Family Applications (1)

Application Number Title Priority Date Filing Date
ES504813A Expired ES8301277A1 (es) 1980-08-19 1981-08-18 Un procedimiento para la preparacion de una nueva sustancia antibiotica sf-2103a.

Country Status (10)

Country Link
US (1) US4404218A (es)
KR (1) KR840001256B1 (es)
CA (1) CA1163220A (es)
CH (1) CH650785A5 (es)
DE (1) DE3132786C2 (es)
ES (1) ES8301277A1 (es)
FR (1) FR2488895A1 (es)
GB (1) GB2087382B (es)
IT (1) IT1209889B (es)
NL (1) NL190197C (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3146190A1 (de) * 1981-11-21 1983-06-16 Hoechst Ag, 6230 Frankfurt Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen
US4647408A (en) * 1983-02-01 1987-03-03 Shionogi & Co., Ltd. Carbapenem-type antibiotics

Also Published As

Publication number Publication date
IT1209889B (it) 1989-08-30
KR830006426A (ko) 1983-09-24
ES504813A0 (es) 1982-12-01
US4404218A (en) 1983-09-13
IT8149120A0 (it) 1981-08-18
NL8103854A (nl) 1982-03-16
CH650785A5 (fr) 1985-08-15
FR2488895A1 (fr) 1982-02-26
DE3132786C2 (de) 1983-12-08
DE3132786A1 (de) 1982-05-13
GB2087382A (en) 1982-05-26
KR840001256B1 (ko) 1984-09-01
FR2488895B1 (es) 1984-03-30
CA1163220A (en) 1984-03-06
NL190197B (nl) 1993-07-01
GB2087382B (en) 1984-07-18
NL190197C (nl) 1993-12-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990903