ES8300734A1 - Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. - Google Patents
Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos.Info
- Publication number
- ES8300734A1 ES8300734A1 ES82508805A ES508805A ES8300734A1 ES 8300734 A1 ES8300734 A1 ES 8300734A1 ES 82508805 A ES82508805 A ES 82508805A ES 508805 A ES508805 A ES 508805A ES 8300734 A1 ES8300734 A1 ES 8300734A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 2
- LFQSCWFLJHTTHZ-HQMMCQRPSA-N Ethanol-14C Chemical compound C[14CH2]O LFQSCWFLJHTTHZ-HQMMCQRPSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/40—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with ozone; by ozonolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8002790 | 1980-01-28 | ||
| GB8039308 | 1980-12-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES508805A0 ES508805A0 (es) | 1982-11-16 |
| ES8300734A1 true ES8300734A1 (es) | 1982-11-16 |
Family
ID=26274313
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES82508805A Expired ES8300734A1 (es) | 1980-01-28 | 1982-01-15 | Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. |
| ES508806A Expired ES8300735A1 (es) | 1980-01-28 | 1982-01-15 | Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES508806A Expired ES8300735A1 (es) | 1980-01-28 | 1982-01-15 | Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4367238A (OSRAM) |
| EP (1) | EP0033614B1 (OSRAM) |
| AR (1) | AR228586A1 (OSRAM) |
| AT (1) | ATE7782T1 (OSRAM) |
| AU (1) | AU537560B2 (OSRAM) |
| CA (1) | CA1195691A (OSRAM) |
| DE (1) | DE3162626D1 (OSRAM) |
| DK (1) | DK34781A (OSRAM) |
| ES (2) | ES8300734A1 (OSRAM) |
| GR (1) | GR73505B (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3110009A1 (de) * | 1981-03-11 | 1982-09-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue benzofuran-derivate, ihre herstellung und verwendung |
| US4857455A (en) * | 1982-11-26 | 1989-08-15 | Syntex (U.S.A) Inc. | Method for the determination of peroxidase using fluorogenic substrates |
| GB8328253D0 (en) * | 1983-10-21 | 1983-11-23 | Shell Int Research | Substituted azetidine derivatives |
| US4911754A (en) * | 1987-07-16 | 1990-03-27 | American Cyanamid Company | Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds |
| US5256686A (en) * | 1989-06-27 | 1993-10-26 | Ono Pharmaceutical Co., Ltd. | Phenylalkan(en)oic acid |
| US6001877A (en) * | 1989-06-27 | 1999-12-14 | Ono Pharmaceutical Co., Ltd. | Phenylalkan(en)oic acid |
| ES2163986B1 (es) * | 1999-07-13 | 2003-02-16 | Menarini Lab | Acidos-alfa-arilpropionicos y arilaceticos como inhibidores de la ciclooxigenasa-ii. |
| US6706917B1 (en) * | 2000-01-04 | 2004-03-16 | Korea Research Institute Of Chemical Technology | Preparing method of 2-phenylalkanoic acid derivatives |
| EP1366763A1 (en) * | 2002-05-28 | 2003-12-03 | Ciba SC Holding AG | Hydroxy diphenyl ether compounds as anti-inflammatory agents |
| EP1481959A1 (de) * | 2003-05-22 | 2004-12-01 | DSM Fine Chemicals Austria Nfg GmbH & Co KG | Verfahren zur Herstellung von Lactonen und von aromatischen Hydroxycarbonsäuren |
| GB201118876D0 (en) * | 2011-11-01 | 2011-12-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| EP3036222A2 (en) * | 2013-08-23 | 2016-06-29 | Virginia Commonwealth University | Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2838522A (en) * | 1956-04-30 | 1958-06-10 | Dow Chemical Co | Phthalides |
| SE363818B (OSRAM) * | 1968-08-15 | 1974-02-04 | Lilly Co Eli | |
| US4120871A (en) * | 1975-05-06 | 1978-10-17 | Fisons Limited | 5-Organosulfonyl, 5-organosulfinyl or 5-haloalkanoyl-benzofuran-2-ones |
-
1981
- 1981-01-21 US US06/226,908 patent/US4367238A/en not_active Expired - Fee Related
- 1981-01-21 CA CA000368943A patent/CA1195691A/en not_active Expired
- 1981-01-22 DE DE8181300283T patent/DE3162626D1/de not_active Expired
- 1981-01-22 EP EP81300283A patent/EP0033614B1/en not_active Expired
- 1981-01-22 AT AT81300283T patent/ATE7782T1/de active
- 1981-01-26 DK DK34781A patent/DK34781A/da not_active Application Discontinuation
- 1981-01-27 GR GR63972A patent/GR73505B/el unknown
- 1981-01-28 AU AU66687/81A patent/AU537560B2/en not_active Ceased
- 1981-01-28 AR AR284092A patent/AR228586A1/es active
-
1982
- 1982-01-15 ES ES82508805A patent/ES8300734A1/es not_active Expired
- 1982-01-15 ES ES508806A patent/ES8300735A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES508805A0 (es) | 1982-11-16 |
| ES508806A0 (es) | 1982-11-16 |
| GR73505B (OSRAM) | 1984-03-06 |
| ATE7782T1 (de) | 1984-06-15 |
| AU537560B2 (en) | 1984-06-28 |
| DK34781A (da) | 1981-07-29 |
| EP0033614A1 (en) | 1981-08-12 |
| US4367238A (en) | 1983-01-04 |
| AU6668781A (en) | 1981-08-06 |
| AR228586A1 (es) | 1983-03-30 |
| CA1195691A (en) | 1985-10-22 |
| ES8300735A1 (es) | 1982-11-16 |
| DE3162626D1 (en) | 1984-07-12 |
| EP0033614B1 (en) | 1984-06-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8300734A1 (es) | Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. | |
| ES8607914A1 (es) | Un procedimiento de preparar un derivado de trans-1,2-diaminociclohexil-amida. | |
| ES8101532A1 (es) | Un procedimiento para la preparacion de acetofenonas substi-tuidas | |
| ES8801221A1 (es) | Un procedimiento para la preparacion de nuevos derivados de ciclopenta(d)pirimidina | |
| ES8502976A1 (es) | 1h-imidazol-1-etanol y esteres derivados del mismo, asi como procedimiento para su obtencion | |
| DK0458965T3 (da) | Fremgangsmåde til fremstilling af vinylethere | |
| JPS5798270A (en) | 1,2-disubstituted-4-chloroimidazole-5-acetic acid derivative | |
| ES8307236A1 (es) | Un procedimiento para la preparacion de ranitidina. | |
| JPS572276A (en) | 1-methyl-5- n-alkyl-n-chloroacetylamino pyrazole-4- carboxylic acid ester derivative, its preparation, and herbicide for paddy rice field | |
| JPS56103197A (en) | Novel d-glucose derivative and antitumor agent containing the same as active constitutent | |
| JPS5470277A (en) | Hydroxyindole derivatives | |
| ES8204990A1 (es) | Procedimiento para preparar sal de (dl)-lisina de 2-(alfa- teoniltio)-tiopropionil-glicina | |
| JPS55151549A (en) | Production of guanidinocaproic ester | |
| ES421284A1 (es) | Procedimiento para la preparacion de derivados de acidos pirrocolinaceticos. | |
| JPS557225A (en) | Preparation of propionic acid derivative | |
| JPS5759856A (en) | Benzene derivative | |
| ES426949A1 (es) | Procedimiento para la preparacion de nuevas 1,4-benzodia- zepinas. | |
| ES8301974A3 (es) | Un procedimiento de preparacion de una 4-fluorofenil-piperi-dina sustituida en posicion 3 | |
| JPS5547651A (en) | Production of sulfoxyimine | |
| JPS5479201A (en) | Preparation of aldehydes | |
| JPS57142970A (en) | Preparation of 4-(3-isopropylamino-2-hydroxy-propoxy) indole | |
| JPS56103196A (en) | Preparation of d-glucose derivative | |
| ES384598A1 (es) | Procedimiento para la preparacion de nuevos derivados basi-cos de pirrol. | |
| JPS56140986A (en) | Production of 5-chloro-3- 4- 2-hydroxyethyl -1-piperazinyl - carbomethyl-2-benzothiazoline or its salt and intermediate | |
| JPS57188538A (en) | Preparations of ether derivatives of cyclopentenones |