ES8206517A1 - Novel dioxolane amine derivative, manufacture and vasodilator - Google Patents

Novel dioxolane amine derivative, manufacture and vasodilator

Info

Publication number
ES8206517A1
ES8206517A1 ES505978A ES505978A ES8206517A1 ES 8206517 A1 ES8206517 A1 ES 8206517A1 ES 505978 A ES505978 A ES 505978A ES 505978 A ES505978 A ES 505978A ES 8206517 A1 ES8206517 A1 ES 8206517A1
Authority
ES
Spain
Prior art keywords
vasodilator
manufacture
obtaining
amine derivative
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES505978A
Other languages
Spanish (es)
Other versions
ES505978A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Investigacion Tecnica y Aplicada SA
Original Assignee
Investigacion Tecnica y Aplicada SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Investigacion Tecnica y Aplicada SA filed Critical Investigacion Tecnica y Aplicada SA
Priority to ES505978A priority Critical patent/ES505978A0/en
Publication of ES8206517A1 publication Critical patent/ES8206517A1/en
Publication of ES505978A0 publication Critical patent/ES505978A0/en
Priority to DE8282109023T priority patent/DE3270277D1/en
Priority to EP82109023A priority patent/EP0076973B1/en
Priority to JP57173128A priority patent/JPS5872580A/en
Granted legal-status Critical Current

Links

Abstract

Procedure for the obtaining 2- (2 '' - benzofuranil) -4-bromometil-2-p-chlorofenil-1,3-dioxalane. Consists of the reaction of a formula (I) cetone with 1 to 3 times molar of epibromhydrine, in the presence of a lewis acid as a catalyst. The reaction starts in a chlorinated solvent at low temperature between 0 and 5c., and completes temperatures between the environment and the ebullition of the reactioning mixture. To the product obtained, a sodium or potassium hydroxide dissolution is added up to ph basic, decayed, washed, dry, separates the solvent and dissolves at reduced pressure. This compound has application for the obtaining of the amino dioxolanica ita 362, of pharmacological activity. (Machine-translation by Google Translate, not legally binding)
ES505978A 1981-10-02 1981-10-02 PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND Granted ES505978A0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES505978A ES505978A0 (en) 1981-10-02 1981-10-02 PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND
DE8282109023T DE3270277D1 (en) 1981-10-02 1982-09-29 A new dioxolanic compound and its method of preparation; a new dioxolanic amine with pharmacological activity, its method of preparation, and the pharmaceutical compositions containing them
EP82109023A EP0076973B1 (en) 1981-10-02 1982-09-29 A new dioxolanic compound and its method of preparation; a new dioxolanic amine with pharmacological activity, its method of preparation, and the pharmaceutical compositions containing them
JP57173128A JPS5872580A (en) 1981-10-02 1982-10-01 Novel dioxolane amine derivative, manufacture and vasodilator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES505978A ES505978A0 (en) 1981-10-02 1981-10-02 PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND

Publications (2)

Publication Number Publication Date
ES8206517A1 true ES8206517A1 (en) 1982-08-16
ES505978A0 ES505978A0 (en) 1982-08-16

Family

ID=8483032

Family Applications (1)

Application Number Title Priority Date Filing Date
ES505978A Granted ES505978A0 (en) 1981-10-02 1981-10-02 PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND

Country Status (2)

Country Link
JP (1) JPS5872580A (en)
ES (1) ES505978A0 (en)

Also Published As

Publication number Publication date
JPS5872580A (en) 1983-04-30
ES505978A0 (en) 1982-08-16

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