ES8206517A1 - Novel dioxolane amine derivative, manufacture and vasodilator - Google Patents
Novel dioxolane amine derivative, manufacture and vasodilatorInfo
- Publication number
- ES8206517A1 ES8206517A1 ES505978A ES505978A ES8206517A1 ES 8206517 A1 ES8206517 A1 ES 8206517A1 ES 505978 A ES505978 A ES 505978A ES 505978 A ES505978 A ES 505978A ES 8206517 A1 ES8206517 A1 ES 8206517A1
- Authority
- ES
- Spain
- Prior art keywords
- vasodilator
- manufacture
- obtaining
- amine derivative
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
Procedure for the obtaining 2- (2 '' - benzofuranil) -4-bromometil-2-p-chlorofenil-1,3-dioxalane. Consists of the reaction of a formula (I) cetone with 1 to 3 times molar of epibromhydrine, in the presence of a lewis acid as a catalyst. The reaction starts in a chlorinated solvent at low temperature between 0 and 5c., and completes temperatures between the environment and the ebullition of the reactioning mixture. To the product obtained, a sodium or potassium hydroxide dissolution is added up to ph basic, decayed, washed, dry, separates the solvent and dissolves at reduced pressure. This compound has application for the obtaining of the amino dioxolanica ita 362, of pharmacological activity. (Machine-translation by Google Translate, not legally binding)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES505978A ES505978A0 (en) | 1981-10-02 | 1981-10-02 | PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND |
DE8282109023T DE3270277D1 (en) | 1981-10-02 | 1982-09-29 | A new dioxolanic compound and its method of preparation; a new dioxolanic amine with pharmacological activity, its method of preparation, and the pharmaceutical compositions containing them |
EP82109023A EP0076973B1 (en) | 1981-10-02 | 1982-09-29 | A new dioxolanic compound and its method of preparation; a new dioxolanic amine with pharmacological activity, its method of preparation, and the pharmaceutical compositions containing them |
JP57173128A JPS5872580A (en) | 1981-10-02 | 1982-10-01 | Novel dioxolane amine derivative, manufacture and vasodilator |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES505978A ES505978A0 (en) | 1981-10-02 | 1981-10-02 | PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8206517A1 true ES8206517A1 (en) | 1982-08-16 |
ES505978A0 ES505978A0 (en) | 1982-08-16 |
Family
ID=8483032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES505978A Granted ES505978A0 (en) | 1981-10-02 | 1981-10-02 | PROCEDURE FOR OBTAINING A NEW DIOXOLANIC COMPOUND |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS5872580A (en) |
ES (1) | ES505978A0 (en) |
-
1981
- 1981-10-02 ES ES505978A patent/ES505978A0/en active Granted
-
1982
- 1982-10-01 JP JP57173128A patent/JPS5872580A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JPS5872580A (en) | 1983-04-30 |
ES505978A0 (en) | 1982-08-16 |
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