ES459725A1 - Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES459725A1
ES459725A1 ES459725A ES459725A ES459725A1 ES 459725 A1 ES459725 A1 ES 459725A1 ES 459725 A ES459725 A ES 459725A ES 459725 A ES459725 A ES 459725A ES 459725 A1 ES459725 A1 ES 459725A1
Authority
ES
Spain
Prior art keywords
propanols
alkylamine
translation
procedure
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES459725A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodes SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodes SA filed Critical Prodes SA
Priority to ES459725A priority Critical patent/ES459725A1/en
Publication of ES459725A1 publication Critical patent/ES459725A1/en
Priority to GR56506A priority patent/GR64959B/en
Priority to YU01381/78A priority patent/YU138178A/en
Priority to IL7854988A priority patent/IL54988A0/en
Priority to IN537/DEL/78A priority patent/IN148020B/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for the obtaining of 1-alkylamine-3- (4 '' - carbomoilmetilfenoxi) -2-propanols of general formula: ** formula ** where r is methyl, style, N-propyl, isopropyl, t-butyl, cyclohexyll, ciclopentilo yr "is hydrogen or bencilo, by reaction of l-alkyl-3azetidinols with p-hydroxyphenylacetamide, the reaction is carried out in autoclave in a half anhydro, it can be carried out with or without solvent, using like eter solvent, methylene methylene, benzene, tolueno or xilano.have place at elevated temperatures and in the presence of acid catalyst (trifluoracetic acid or ions exchanger) or a base as catalyst (sodium hydroxide potassium hydroxide or ions exchanger) to the compound is isolated by crystallization, these compounds have therapeutic properties as blockers (3-adrenergic, for the treatment of hypertension). (Machine-translation by Google Translate, not legally binding)
ES459725A 1977-06-13 1977-06-13 Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding) Expired ES459725A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES459725A ES459725A1 (en) 1977-06-13 1977-06-13 Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding)
GR56506A GR64959B (en) 1977-06-13 1978-06-12 Method for the preparation of 1-alkylanin-3-(4'-carbamoilo-methyl-fenoxy)-2-propanoles
YU01381/78A YU138178A (en) 1977-06-13 1978-06-12 Process for obtaining 1-alkylamino-3-94-carbamoylmethylphenoxy0-2-propanol
IL7854988A IL54988A0 (en) 1977-06-13 1978-06-23 Phenyl acetamide derivatives and process for their prepararion
IN537/DEL/78A IN148020B (en) 1977-06-13 1978-07-21

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES459725A ES459725A1 (en) 1977-06-13 1977-06-13 Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES459725A1 true ES459725A1 (en) 1978-04-01

Family

ID=8474004

Family Applications (1)

Application Number Title Priority Date Filing Date
ES459725A Expired ES459725A1 (en) 1977-06-13 1977-06-13 Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
ES (1) ES459725A1 (en)
GR (1) GR64959B (en)
IN (1) IN148020B (en)
YU (1) YU138178A (en)

Also Published As

Publication number Publication date
GR64959B (en) 1980-06-10
IN148020B (en) 1980-09-27
YU138178A (en) 1982-10-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991102