ES459725A1 - Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES459725A1 ES459725A1 ES459725A ES459725A ES459725A1 ES 459725 A1 ES459725 A1 ES 459725A1 ES 459725 A ES459725 A ES 459725A ES 459725 A ES459725 A ES 459725A ES 459725 A1 ES459725 A1 ES 459725A1
- Authority
- ES
- Spain
- Prior art keywords
- propanols
- alkylamine
- translation
- procedure
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for the obtaining of 1-alkylamine-3- (4 '' - carbomoilmetilfenoxi) -2-propanols of general formula: ** formula ** where r is methyl, style, N-propyl, isopropyl, t-butyl, cyclohexyll, ciclopentilo yr "is hydrogen or bencilo, by reaction of l-alkyl-3azetidinols with p-hydroxyphenylacetamide, the reaction is carried out in autoclave in a half anhydro, it can be carried out with or without solvent, using like eter solvent, methylene methylene, benzene, tolueno or xilano.have place at elevated temperatures and in the presence of acid catalyst (trifluoracetic acid or ions exchanger) or a base as catalyst (sodium hydroxide potassium hydroxide or ions exchanger) to the compound is isolated by crystallization, these compounds have therapeutic properties as blockers (3-adrenergic, for the treatment of hypertension). (Machine-translation by Google Translate, not legally binding)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES459725A ES459725A1 (en) | 1977-06-13 | 1977-06-13 | Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding) |
GR56506A GR64959B (en) | 1977-06-13 | 1978-06-12 | Method for the preparation of 1-alkylanin-3-(4'-carbamoilo-methyl-fenoxy)-2-propanoles |
YU01381/78A YU138178A (en) | 1977-06-13 | 1978-06-12 | Process for obtaining 1-alkylamino-3-94-carbamoylmethylphenoxy0-2-propanol |
IL7854988A IL54988A0 (en) | 1977-06-13 | 1978-06-23 | Phenyl acetamide derivatives and process for their prepararion |
IN537/DEL/78A IN148020B (en) | 1977-06-13 | 1978-07-21 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES459725A ES459725A1 (en) | 1977-06-13 | 1977-06-13 | Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES459725A1 true ES459725A1 (en) | 1978-04-01 |
Family
ID=8474004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES459725A Expired ES459725A1 (en) | 1977-06-13 | 1977-06-13 | Procedure for the obtaining of 1-alkylamine-3- (4'carbamoilmetilfenoxi) -2-propanols. (Machine-translation by Google Translate, not legally binding) |
Country Status (4)
Country | Link |
---|---|
ES (1) | ES459725A1 (en) |
GR (1) | GR64959B (en) |
IN (1) | IN148020B (en) |
YU (1) | YU138178A (en) |
-
1977
- 1977-06-13 ES ES459725A patent/ES459725A1/en not_active Expired
-
1978
- 1978-06-12 YU YU01381/78A patent/YU138178A/en unknown
- 1978-06-12 GR GR56506A patent/GR64959B/en unknown
- 1978-07-21 IN IN537/DEL/78A patent/IN148020B/en unknown
Also Published As
Publication number | Publication date |
---|---|
GR64959B (en) | 1980-06-10 |
IN148020B (en) | 1980-09-27 |
YU138178A (en) | 1982-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19991102 |