ES8205405A1 - Un procedimiento para producir compuestos de espirobenzofu- ranona - Google Patents

Un procedimiento para producir compuestos de espirobenzofu- ranona

Info

Publication number
ES8205405A1
ES8205405A1 ES497669A ES497669A ES8205405A1 ES 8205405 A1 ES8205405 A1 ES 8205405A1 ES 497669 A ES497669 A ES 497669A ES 497669 A ES497669 A ES 497669A ES 8205405 A1 ES8205405 A1 ES 8205405A1
Authority
ES
Spain
Prior art keywords
substituted
production
spirobenzofuranones
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497669A
Other languages
English (en)
Other versions
ES497669A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5508279A external-priority patent/JPS55147271A/ja
Priority claimed from JP8055179A external-priority patent/JPS5931511B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES497669A0 publication Critical patent/ES497669A0/es
Publication of ES8205405A1 publication Critical patent/ES8205405A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE ESOIROBENZOFURANONA DE FORMULA (I), EN LA QUE EL ANILLO A ES UN ANILLO DE BENCENO SUSTITUIDO, POR AL MENOS, UNO DE VARIOS TIPOS DE RADIALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE EL ANILLO B ES UN ANILLO DE BENCENO SUSTITUIDO POR, AL MENOS, UNO DE VARIOS TIPOS DE RADIALES, CON UN REACTIVO TAL COMO UN AGENTE ALCOHILANTE, OXIDANTE, REDUCTOR, ESTERIFICANTE, UN HIPOHALOGENITO O AGUA, EN UN DISOLVENTE INERTE ADECUADO, A UNA TEMPERATURA NO SUPERIOR AL PUNTO DE EBULLICION DEL DISOLVENTE. EL REACTIVO HA DE SER EL ADECUADO PARA CONVERTIR AL MENOS UNO DE LOS SUSTITUYENTES DEL ANILLO B EN OTRO DE LOS SUSTITUYENTES DEL ANILLO A. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIULCEROSOS, ANTIINFLAMATORIOS, ANALGESICOS Y PARA EL TRATAMIENTO DE GASTRITIS, LUMBAGO Y ARTRITIS.
ES497669A 1979-05-04 1980-12-12 Un procedimiento para producir compuestos de espirobenzofu- ranona Expired ES8205405A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5508279A JPS55147271A (en) 1979-05-04 1979-05-04 Spiro compound and its preparation
JP8055179A JPS5931511B2 (ja) 1979-06-25 1979-06-25 スピロ化合物およびその製造方法

Publications (2)

Publication Number Publication Date
ES497669A0 ES497669A0 (es) 1982-06-01
ES8205405A1 true ES8205405A1 (es) 1982-06-01

Family

ID=26395929

Family Applications (4)

Application Number Title Priority Date Filing Date
ES491150A Granted ES491150A0 (es) 1979-05-04 1980-05-03 Un procedimiento para producir compuestos de espirobenzofu- ranona
ES497669A Expired ES8205405A1 (es) 1979-05-04 1980-12-12 Un procedimiento para producir compuestos de espirobenzofu- ranona
ES502178A Expired ES8203873A1 (es) 1979-05-04 1981-05-13 Un procedimiento para obtener un compuesto de espirobenzofu-ranona
ES502179A Expired ES8203874A1 (es) 1979-05-04 1981-05-13 Un procedimiento para obtener 7-acetilespiro(benzo(b) furan-2(3h)-1'-ciclopropano)-3-ona

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES491150A Granted ES491150A0 (es) 1979-05-04 1980-05-03 Un procedimiento para producir compuestos de espirobenzofu- ranona

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES502178A Expired ES8203873A1 (es) 1979-05-04 1981-05-13 Un procedimiento para obtener un compuesto de espirobenzofu-ranona
ES502179A Expired ES8203874A1 (es) 1979-05-04 1981-05-13 Un procedimiento para obtener 7-acetilespiro(benzo(b) furan-2(3h)-1'-ciclopropano)-3-ona

Country Status (10)

Country Link
EP (3) EP0038576B1 (es)
AT (1) AT383122B (es)
AU (1) AU534940B2 (es)
CA (3) CA1150287A (es)
DE (1) DE3063660D1 (es)
DK (1) DK153551C (es)
ES (4) ES491150A0 (es)
GR (1) GR66729B (es)
NO (1) NO155053C (es)
SU (1) SU1022658A3 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK149891C (da) * 1977-12-27 1987-06-15 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af spirobenzofuranon-forbindelser eller salte deraf med uorganiske eller organiske syrer eller alkalimetaller

Also Published As

Publication number Publication date
NO155053C (no) 1987-02-04
ES497669A0 (es) 1982-06-01
ES502178A0 (es) 1982-04-01
EP0039091B1 (en) 1984-05-30
DK153551C (da) 1988-12-05
AU5790380A (en) 1980-11-06
DK153551B (da) 1988-07-25
EP0038576B1 (en) 1984-04-11
DE3063660D1 (en) 1983-07-14
CA1150287A (en) 1983-07-19
EP0038576A3 (en) 1981-11-18
NO155053B (no) 1986-10-27
ES8104996A1 (es) 1981-05-16
AT383122B (de) 1987-05-25
GR66729B (es) 1981-04-17
CA1138469A (en) 1982-12-28
DK184680A (da) 1980-11-05
EP0038576A2 (en) 1981-10-28
ES502179A0 (es) 1982-04-01
CA1140562A (en) 1983-02-01
ATA233880A (de) 1986-10-15
EP0039091A1 (en) 1981-11-04
EP0018830A3 (en) 1980-12-10
ES491150A0 (es) 1981-05-16
EP0018830A2 (en) 1980-11-12
ES8203873A1 (es) 1982-04-01
EP0018830B1 (en) 1983-06-08
ES8203874A1 (es) 1982-04-01
AU534940B2 (en) 1984-02-23
SU1022658A3 (ru) 1983-06-07
NO801290L (no) 1980-11-05

Similar Documents

Publication Publication Date Title
AU548268B2 (en) 2-ammo-5-hydroxy-4-methylpyrimidinme derivatives
IE45256L (en) Quinazolone derivatives
MY108967A (en) Triazolopyridazine compounds, their production and use
HUT45983A (en) Process for production of derivatives of imidazolidinone
GB1411583A (en) Aminophenyl-substituted alkyl-heterocyclic derivatives and processes for producing them
ES8800235A1 (es) Un procedimiento para preparar un isomero sin de un compues-to de cefem
GB1325386A (en) Quinazoline derivatives processes for producing them and compositions containing them
ES8104996A1 (es) Un procedimiento para producir compuestos de espirobenzofu- ranona
ES8606880A1 (es) Un procedimiento para la preparacion de nuevos peptidos.
ES8401926A1 (es) Un procedimiento para la preparacion de un compuesto de hidroxibencilaminobenceno, dotado de propiedades antiinflamatorias.
GB1373567A (en) Substituted acetic acid derivatives and the production thereof
GB1509547A (en) Tetracycline derivatives and process for preparing them
ES8104269A1 (es) Procedimiento para la preparacion de nuevos derivados de 3-amino-1-benzoxepina
ES8200687A1 (es) Un procedimiento para la preparacion de nuevos compuestos amidicos de penicilina
ES8304923A1 (es) Un procedimiento para la preparacion de un peptido.
GB1203430A (en) Heterocyclic spiro compounds
GB1325280A (en) 3-substituted-as-triazino-5,6-c-quinolines
GB1187071A (en) N-Amino-Substituted 4-Anilino-Pyridines
ES470462A1 (es) Procedimiento para producir imidazol-2-carbamatos
GB1385742A (en) Imidazole derivatives
IE40182B1 (en) Aminoethanol derivatives
GB1434645A (en) Tetrazole coumarin derivatives
ES476330A1 (es) Un metodo para producir un compuesto espiro
GB1360056A (en) Processes for the preparation of derivatives of indolylacetic acid
GB1385123A (en) Substituted benzimidazoles their preparation and uses therefor