ES8205405A1 - Un procedimiento para producir compuestos de espirobenzofu- ranona - Google Patents
Un procedimiento para producir compuestos de espirobenzofu- ranonaInfo
- Publication number
- ES8205405A1 ES8205405A1 ES497669A ES497669A ES8205405A1 ES 8205405 A1 ES8205405 A1 ES 8205405A1 ES 497669 A ES497669 A ES 497669A ES 497669 A ES497669 A ES 497669A ES 8205405 A1 ES8205405 A1 ES 8205405A1
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- production
- spirobenzofuranones
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE ESOIROBENZOFURANONA DE FORMULA (I), EN LA QUE EL ANILLO A ES UN ANILLO DE BENCENO SUSTITUIDO, POR AL MENOS, UNO DE VARIOS TIPOS DE RADIALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE EL ANILLO B ES UN ANILLO DE BENCENO SUSTITUIDO POR, AL MENOS, UNO DE VARIOS TIPOS DE RADIALES, CON UN REACTIVO TAL COMO UN AGENTE ALCOHILANTE, OXIDANTE, REDUCTOR, ESTERIFICANTE, UN HIPOHALOGENITO O AGUA, EN UN DISOLVENTE INERTE ADECUADO, A UNA TEMPERATURA NO SUPERIOR AL PUNTO DE EBULLICION DEL DISOLVENTE. EL REACTIVO HA DE SER EL ADECUADO PARA CONVERTIR AL MENOS UNO DE LOS SUSTITUYENTES DEL ANILLO B EN OTRO DE LOS SUSTITUYENTES DEL ANILLO A. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIULCEROSOS, ANTIINFLAMATORIOS, ANALGESICOS Y PARA EL TRATAMIENTO DE GASTRITIS, LUMBAGO Y ARTRITIS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5508279A JPS55147271A (en) | 1979-05-04 | 1979-05-04 | Spiro compound and its preparation |
JP8055179A JPS5931511B2 (ja) | 1979-06-25 | 1979-06-25 | スピロ化合物およびその製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES497669A0 ES497669A0 (es) | 1982-06-01 |
ES8205405A1 true ES8205405A1 (es) | 1982-06-01 |
Family
ID=26395929
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES491150A Granted ES491150A0 (es) | 1979-05-04 | 1980-05-03 | Un procedimiento para producir compuestos de espirobenzofu- ranona |
ES497669A Expired ES8205405A1 (es) | 1979-05-04 | 1980-12-12 | Un procedimiento para producir compuestos de espirobenzofu- ranona |
ES502178A Expired ES8203873A1 (es) | 1979-05-04 | 1981-05-13 | Un procedimiento para obtener un compuesto de espirobenzofu-ranona |
ES502179A Expired ES8203874A1 (es) | 1979-05-04 | 1981-05-13 | Un procedimiento para obtener 7-acetilespiro(benzo(b) furan-2(3h)-1'-ciclopropano)-3-ona |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES491150A Granted ES491150A0 (es) | 1979-05-04 | 1980-05-03 | Un procedimiento para producir compuestos de espirobenzofu- ranona |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES502178A Expired ES8203873A1 (es) | 1979-05-04 | 1981-05-13 | Un procedimiento para obtener un compuesto de espirobenzofu-ranona |
ES502179A Expired ES8203874A1 (es) | 1979-05-04 | 1981-05-13 | Un procedimiento para obtener 7-acetilespiro(benzo(b) furan-2(3h)-1'-ciclopropano)-3-ona |
Country Status (10)
Country | Link |
---|---|
EP (3) | EP0038576B1 (es) |
AT (1) | AT383122B (es) |
AU (1) | AU534940B2 (es) |
CA (3) | CA1150287A (es) |
DE (1) | DE3063660D1 (es) |
DK (1) | DK153551C (es) |
ES (4) | ES491150A0 (es) |
GR (1) | GR66729B (es) |
NO (1) | NO155053C (es) |
SU (1) | SU1022658A3 (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK149891C (da) * | 1977-12-27 | 1987-06-15 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af spirobenzofuranon-forbindelser eller salte deraf med uorganiske eller organiske syrer eller alkalimetaller |
-
1980
- 1980-04-23 GR GR61757A patent/GR66729B/el unknown
- 1980-04-29 DK DK184680A patent/DK153551C/da not_active IP Right Cessation
- 1980-04-30 AU AU57903/80A patent/AU534940B2/en not_active Ceased
- 1980-05-01 EP EP81104398A patent/EP0038576B1/en not_active Expired
- 1980-05-01 EP EP80301431A patent/EP0018830B1/en not_active Expired
- 1980-05-01 DE DE8080301431T patent/DE3063660D1/de not_active Expired
- 1980-05-01 EP EP81104399A patent/EP0039091B1/en not_active Expired
- 1980-05-01 CA CA000351051A patent/CA1150287A/en not_active Expired
- 1980-05-02 NO NO801290A patent/NO155053C/no unknown
- 1980-05-02 AT AT0233880A patent/AT383122B/de not_active IP Right Cessation
- 1980-05-03 ES ES491150A patent/ES491150A0/es active Granted
- 1980-05-05 SU SU802917050A patent/SU1022658A3/ru active
- 1980-12-12 ES ES497669A patent/ES8205405A1/es not_active Expired
-
1981
- 1981-05-13 ES ES502178A patent/ES8203873A1/es not_active Expired
- 1981-05-13 ES ES502179A patent/ES8203874A1/es not_active Expired
-
1982
- 1982-01-18 CA CA000394406A patent/CA1140562A/en not_active Expired
- 1982-01-18 CA CA000394405A patent/CA1138469A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
NO155053C (no) | 1987-02-04 |
ES497669A0 (es) | 1982-06-01 |
ES502178A0 (es) | 1982-04-01 |
EP0039091B1 (en) | 1984-05-30 |
DK153551C (da) | 1988-12-05 |
AU5790380A (en) | 1980-11-06 |
DK153551B (da) | 1988-07-25 |
EP0038576B1 (en) | 1984-04-11 |
DE3063660D1 (en) | 1983-07-14 |
CA1150287A (en) | 1983-07-19 |
EP0038576A3 (en) | 1981-11-18 |
NO155053B (no) | 1986-10-27 |
ES8104996A1 (es) | 1981-05-16 |
AT383122B (de) | 1987-05-25 |
GR66729B (es) | 1981-04-17 |
CA1138469A (en) | 1982-12-28 |
DK184680A (da) | 1980-11-05 |
EP0038576A2 (en) | 1981-10-28 |
ES502179A0 (es) | 1982-04-01 |
CA1140562A (en) | 1983-02-01 |
ATA233880A (de) | 1986-10-15 |
EP0039091A1 (en) | 1981-11-04 |
EP0018830A3 (en) | 1980-12-10 |
ES491150A0 (es) | 1981-05-16 |
EP0018830A2 (en) | 1980-11-12 |
ES8203873A1 (es) | 1982-04-01 |
EP0018830B1 (en) | 1983-06-08 |
ES8203874A1 (es) | 1982-04-01 |
AU534940B2 (en) | 1984-02-23 |
SU1022658A3 (ru) | 1983-06-07 |
NO801290L (no) | 1980-11-05 |
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