ES8104269A1 - Procedimiento para la preparacion de nuevos derivados de 3-amino-1-benzoxepina - Google Patents
Procedimiento para la preparacion de nuevos derivados de 3-amino-1-benzoxepinaInfo
- Publication number
- ES8104269A1 ES8104269A1 ES493926A ES493926A ES8104269A1 ES 8104269 A1 ES8104269 A1 ES 8104269A1 ES 493926 A ES493926 A ES 493926A ES 493926 A ES493926 A ES 493926A ES 8104269 A1 ES8104269 A1 ES 8104269A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- alkyl
- independently
- another
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 3-AMINO-1-BENZOXEPINA, DE FORMULA (I) DONDE R1, R2, R3, R4, R5 Y R6 SON DISTINTOS TIPOS DE ATOMOS O RADICALES. SE OBTIENEN REDUCIENDO DERIVADOS DE 3-AMINO-1-BENZOXEPIN-5(2H)-ONA, DE FORMULA (II), EN UN DISOLVENTE INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE -70GC Y LA TEMPERATURA DE REFLUJO DEL DISOLVENTE EMPLEADO. SE REALIZA LA REDUCCION EN PRESENCIA DE UN ACIDO ORGANICO O INORGANICO CON UN AGENTE REDUCTOR DEL TIPO HIDRURO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS Y TERAPEUTICAS. *FORMULA* E
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792931399 DE2931399A1 (de) | 1979-08-02 | 1979-08-02 | Neue 3-amino-1-benzoxepin-derivate und ihre salze, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES493926A0 ES493926A0 (es) | 1981-04-01 |
| ES8104269A1 true ES8104269A1 (es) | 1981-04-01 |
Family
ID=6077478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493926A Expired ES8104269A1 (es) | 1979-08-02 | 1980-08-01 | Procedimiento para la preparacion de nuevos derivados de 3-amino-1-benzoxepina |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4279904A (es) |
| EP (1) | EP0024560B1 (es) |
| JP (1) | JPS5649374A (es) |
| AT (1) | ATE3038T1 (es) |
| AU (1) | AU532394B2 (es) |
| CA (1) | CA1161857A (es) |
| DD (1) | DD154018A5 (es) |
| DE (2) | DE2931399A1 (es) |
| DK (1) | DK152044C (es) |
| ES (1) | ES8104269A1 (es) |
| FI (1) | FI802384A (es) |
| GR (1) | GR69358B (es) |
| HU (1) | HU181736B (es) |
| IE (1) | IE50100B1 (es) |
| IL (1) | IL60552A (es) |
| NO (1) | NO155135C (es) |
| NZ (1) | NZ194329A (es) |
| PH (1) | PH15870A (es) |
| PT (1) | PT71600A (es) |
| SU (1) | SU1017170A3 (es) |
| ZA (1) | ZA804548B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556656A (en) * | 1978-10-23 | 1985-12-03 | The Upjohn Company | 2-Benzoxepins |
| DE3440296A1 (de) * | 1984-11-05 | 1986-05-15 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 3-amino-2,3-dihydro-1-benzoxepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3440295A1 (de) * | 1984-11-05 | 1986-05-15 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Verfahren zur diastereoselektiven reduktion von 3-amino-1-benzoxepin-5(2h)-onen |
| AU597671B2 (en) * | 1986-06-20 | 1990-06-07 | Suntory Limited | 2-Phenylbenzoxepin derivative |
| JP2931986B2 (ja) * | 1989-02-17 | 1999-08-09 | 武田薬品工業株式会社 | アラルキルアミン誘導体 |
| CN103554077B (zh) * | 2013-10-29 | 2014-12-17 | 云南烟草科学研究院 | 一种色酮类化合物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1593760A1 (de) * | 1967-02-01 | 1972-06-08 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung neuer Benz-epinderivate |
| US3991082A (en) * | 1975-03-03 | 1976-11-09 | Warner-Lambert Company | 4-Substituted-2,3-dihydro-1-benzoxepin-3,5-diones and tautomers |
| US4153612A (en) * | 1977-10-31 | 1979-05-08 | The Upjohn Company | 2-Benzoxepins |
-
1979
- 1979-08-02 DE DE19792931399 patent/DE2931399A1/de not_active Withdrawn
-
1980
- 1980-07-03 IE IE1386/80A patent/IE50100B1/en unknown
- 1980-07-11 NZ NZ194329A patent/NZ194329A/xx unknown
- 1980-07-11 IL IL60552A patent/IL60552A/xx unknown
- 1980-07-14 AU AU60390/80A patent/AU532394B2/en not_active Ceased
- 1980-07-16 PH PH24296A patent/PH15870A/en unknown
- 1980-07-24 PT PT71600A patent/PT71600A/pt unknown
- 1980-07-28 US US06/173,075 patent/US4279904A/en not_active Expired - Lifetime
- 1980-07-28 ZA ZA00804548A patent/ZA804548B/xx unknown
- 1980-07-29 EP EP80104467A patent/EP0024560B1/de not_active Expired
- 1980-07-29 DE DE8080104467T patent/DE3062741D1/de not_active Expired
- 1980-07-29 AT AT80104467T patent/ATE3038T1/de not_active IP Right Cessation
- 1980-07-29 HU HU801889A patent/HU181736B/hu unknown
- 1980-07-30 FI FI802384A patent/FI802384A/fi not_active Application Discontinuation
- 1980-07-31 GR GR62576A patent/GR69358B/el unknown
- 1980-08-01 DD DD80223066A patent/DD154018A5/de unknown
- 1980-08-01 SU SU802953852A patent/SU1017170A3/ru active
- 1980-08-01 ES ES493926A patent/ES8104269A1/es not_active Expired
- 1980-08-01 CA CA000357545A patent/CA1161857A/en not_active Expired
- 1980-08-01 NO NO802325A patent/NO155135C/no unknown
- 1980-08-01 DK DK333380A patent/DK152044C/da not_active IP Right Cessation
- 1980-08-01 JP JP10515880A patent/JPS5649374A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3062741D1 (en) | 1983-05-19 |
| NZ194329A (en) | 1982-05-25 |
| PT71600A (en) | 1980-08-01 |
| CA1161857A (en) | 1984-02-07 |
| PH15870A (en) | 1983-04-13 |
| ES493926A0 (es) | 1981-04-01 |
| FI802384A (fi) | 1981-02-03 |
| DD154018A5 (de) | 1982-02-17 |
| DE2931399A1 (de) | 1981-02-26 |
| AU532394B2 (en) | 1983-09-29 |
| EP0024560A1 (de) | 1981-03-11 |
| SU1017170A3 (ru) | 1983-05-07 |
| JPS6360750B2 (es) | 1988-11-25 |
| IE801386L (en) | 1981-02-02 |
| EP0024560B1 (de) | 1983-04-13 |
| GR69358B (es) | 1982-05-20 |
| NO155135C (no) | 1987-02-18 |
| DK152044B (da) | 1988-01-25 |
| NO155135B (no) | 1986-11-10 |
| IE50100B1 (en) | 1986-02-19 |
| HU181736B (en) | 1983-11-28 |
| DK152044C (da) | 1988-06-20 |
| DK333380A (da) | 1981-02-03 |
| AU6039080A (en) | 1981-02-05 |
| US4279904A (en) | 1981-07-21 |
| JPS5649374A (en) | 1981-05-02 |
| ATE3038T1 (de) | 1983-04-15 |
| NO802325L (no) | 1981-02-03 |
| ZA804548B (en) | 1981-07-29 |
| IL60552A (en) | 1984-10-31 |
| IL60552A0 (en) | 1980-09-16 |
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