ES8203382A1 - Un procedimiento para la preparacion de indolo benzoxazinas. - Google Patents
Un procedimiento para la preparacion de indolo benzoxazinas.Info
- Publication number
- ES8203382A1 ES8203382A1 ES497064A ES497064A ES8203382A1 ES 8203382 A1 ES8203382 A1 ES 8203382A1 ES 497064 A ES497064 A ES 497064A ES 497064 A ES497064 A ES 497064A ES 8203382 A1 ES8203382 A1 ES 8203382A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- indolobenzoxazines
- preparing
- processes
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
UN PROCEDIMIENTO PARA LA PREPARCION DE INDOLOBENZOXAZINAS. CONSISTE EN SOMETER A REACCION DE REDUCCION A UN COMPUEXTO DE FORMULA GENERAL (I), CON LO QUE SE OBTIENE EL COMPUESTO (II), EL CUAL CUANDO R2 ES HIDROGENO SE PUEDE HACER REACCIONAR CON UNA GENTE HALOGENANTE PARA OBTENER EL COMPUESTO (II), EN QUE R2 ES HALOGENO. R ES H, ALQUILO O ARILO; R'' ES H, ALQUILO, ARALQUILO, CICLOALQUILO O ALQUENILO; R2 ES H, HALOGENO O ALQUILO; R3 ES H, ALQUILO O ARALQUILO, Y R4 ES H, HALOGENO, ALQUILO, HIDROXI O ALCOXI.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/096,966 US4238486A (en) | 1979-11-23 | 1979-11-23 | Indolobenzoxazines |
Publications (2)
Publication Number | Publication Date |
---|---|
ES497064A0 ES497064A0 (es) | 1982-04-01 |
ES8203382A1 true ES8203382A1 (es) | 1982-04-01 |
Family
ID=22259990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497064A Expired ES8203382A1 (es) | 1979-11-23 | 1980-11-21 | Un procedimiento para la preparacion de indolo benzoxazinas. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4238486A (es) |
EP (1) | EP0033767B1 (es) |
JP (1) | JPS5687583A (es) |
AT (1) | ATE8144T1 (es) |
AU (1) | AU539028B2 (es) |
DE (1) | DE3068379D1 (es) |
DK (1) | DK497580A (es) |
ES (1) | ES8203382A1 (es) |
GR (1) | GR71633B (es) |
IE (1) | IE50515B1 (es) |
NZ (1) | NZ195504A (es) |
PT (1) | PT72089B (es) |
ZA (1) | ZA807295B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2476649A1 (fr) * | 1980-02-26 | 1981-08-28 | Roussel Uclaf | Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
FR2479830A1 (fr) * | 1980-04-03 | 1981-10-09 | Roussel Uclaf | Nouveaux derives de l'indolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
CA1204745A (en) * | 1981-11-20 | 1986-05-20 | Merck Co. | Hexahydronaphth (1,2-b) -1,4 -oxazines |
US4420480A (en) * | 1981-11-20 | 1983-12-13 | Merck & Co., Inc. | Hexahydronaphth[1,2-b]-1,4-oxazines |
FR2522658A1 (fr) * | 1982-03-05 | 1983-09-09 | Roussel Uclaf | Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation |
FR2526797A1 (fr) * | 1982-05-12 | 1983-11-18 | Roussel Uclaf | Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
FR2533215A1 (fr) * | 1982-09-20 | 1984-03-23 | Roussel Uclaf | Nouveaux derives de la c-homo 9-oxaergoline, leurs sels, procede de preparation et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
US4587336A (en) * | 1984-08-15 | 1986-05-06 | Eli Lilly And Company | Partially hydrogenated intermediate pyrazolo, pyrimido and thiazolo[1,4]benzoxazines |
US4552956A (en) * | 1984-08-15 | 1985-11-12 | Eli Lilly And Company | Partially hydrogenated pyrazolo, pyrimido and thiazolo[1,4]benzoxazines |
FR2578254B1 (fr) * | 1985-03-01 | 1987-03-06 | Roussel Uclaf | Nouveaux derives de la pyrazolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant, et des intermediaires |
US4774243A (en) * | 1985-12-24 | 1988-09-27 | Merck & Co., Inc. | Dopamine agonists for treating elevated intraocular pressure |
FR2594828B1 (fr) * | 1986-02-24 | 1988-07-01 | Roussel Uclaf | Derives du tetrahydrobenz (c,d) indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et intermediaires |
US5466689A (en) * | 1993-02-08 | 1995-11-14 | Takeda Chemical Industries, Ltd. | Morpholine derivatives and their use |
US6906096B2 (en) * | 2002-06-28 | 2005-06-14 | Irm Llc | 4,7-Disubstituted indoles and methods of making |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3968111A (en) * | 1974-12-06 | 1976-07-06 | Eli Lilly And Company | 8,8-Disubstituted-6-methylergolines and related compounds |
-
1979
- 1979-11-23 US US06/096,966 patent/US4238486A/en not_active Expired - Lifetime
-
1980
- 1980-11-10 NZ NZ195504A patent/NZ195504A/en unknown
- 1980-11-19 IE IE2399/80A patent/IE50515B1/en unknown
- 1980-11-20 GR GR63414A patent/GR71633B/el unknown
- 1980-11-20 DE DE8080107206T patent/DE3068379D1/de not_active Expired
- 1980-11-20 EP EP80107206A patent/EP0033767B1/en not_active Expired
- 1980-11-20 AT AT80107206T patent/ATE8144T1/de not_active IP Right Cessation
- 1980-11-21 PT PT72089A patent/PT72089B/pt unknown
- 1980-11-21 DK DK497580A patent/DK497580A/da not_active Application Discontinuation
- 1980-11-21 AU AU64594/80A patent/AU539028B2/en not_active Ceased
- 1980-11-21 ZA ZA00807295A patent/ZA807295B/xx unknown
- 1980-11-21 ES ES497064A patent/ES8203382A1/es not_active Expired
- 1980-11-25 JP JP16476880A patent/JPS5687583A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
PT72089A (en) | 1980-12-01 |
DE3068379D1 (en) | 1984-08-02 |
GR71633B (es) | 1983-06-20 |
NZ195504A (en) | 1984-12-14 |
IE50515B1 (en) | 1986-04-30 |
ES497064A0 (es) | 1982-04-01 |
JPH0227358B2 (es) | 1990-06-15 |
DK497580A (da) | 1981-05-24 |
AU6459480A (en) | 1981-05-28 |
AU539028B2 (en) | 1984-09-06 |
PT72089B (en) | 1982-09-02 |
IE802399L (en) | 1981-05-23 |
ATE8144T1 (de) | 1984-07-15 |
EP0033767B1 (en) | 1984-06-27 |
US4238486A (en) | 1980-12-09 |
EP0033767A1 (en) | 1981-08-19 |
ZA807295B (en) | 1982-06-30 |
JPS5687583A (en) | 1981-07-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960401 |