DE3068379D1 - Indolobenzoxazines, processes for preparing and pharmaceutical compositions containing the same - Google Patents

Indolobenzoxazines, processes for preparing and pharmaceutical compositions containing the same

Info

Publication number
DE3068379D1
DE3068379D1 DE8080107206T DE3068379T DE3068379D1 DE 3068379 D1 DE3068379 D1 DE 3068379D1 DE 8080107206 T DE8080107206 T DE 8080107206T DE 3068379 T DE3068379 T DE 3068379T DE 3068379 D1 DE3068379 D1 DE 3068379D1
Authority
DE
Germany
Prior art keywords
alkyl
indolobenzoxazines
preparing
processes
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080107206T
Other languages
English (en)
Inventor
James H Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE3068379D1 publication Critical patent/DE3068379D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DE8080107206T 1979-11-23 1980-11-20 Indolobenzoxazines, processes for preparing and pharmaceutical compositions containing the same Expired DE3068379D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/096,966 US4238486A (en) 1979-11-23 1979-11-23 Indolobenzoxazines

Publications (1)

Publication Number Publication Date
DE3068379D1 true DE3068379D1 (en) 1984-08-02

Family

ID=22259990

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080107206T Expired DE3068379D1 (en) 1979-11-23 1980-11-20 Indolobenzoxazines, processes for preparing and pharmaceutical compositions containing the same

Country Status (13)

Country Link
US (1) US4238486A (de)
EP (1) EP0033767B1 (de)
JP (1) JPS5687583A (de)
AT (1) ATE8144T1 (de)
AU (1) AU539028B2 (de)
DE (1) DE3068379D1 (de)
DK (1) DK497580A (de)
ES (1) ES8203382A1 (de)
GR (1) GR71633B (de)
IE (1) IE50515B1 (de)
NZ (1) NZ195504A (de)
PT (1) PT72089B (de)
ZA (1) ZA807295B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476649A1 (fr) * 1980-02-26 1981-08-28 Roussel Uclaf Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2479830A1 (fr) * 1980-04-03 1981-10-09 Roussel Uclaf Nouveaux derives de l'indolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
CA1204745A (en) * 1981-11-20 1986-05-20 Merck Co. Hexahydronaphth (1,2-b) -1,4 -oxazines
FR2522658A1 (fr) * 1982-03-05 1983-09-09 Roussel Uclaf Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation
FR2526797A1 (fr) * 1982-05-12 1983-11-18 Roussel Uclaf Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2533215A1 (fr) * 1982-09-20 1984-03-23 Roussel Uclaf Nouveaux derives de la c-homo 9-oxaergoline, leurs sels, procede de preparation et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
US4552956A (en) * 1984-08-15 1985-11-12 Eli Lilly And Company Partially hydrogenated pyrazolo, pyrimido and thiazolo[1,4]benzoxazines
US4587336A (en) * 1984-08-15 1986-05-06 Eli Lilly And Company Partially hydrogenated intermediate pyrazolo, pyrimido and thiazolo[1,4]benzoxazines
FR2578254B1 (fr) * 1985-03-01 1987-03-06 Roussel Uclaf Nouveaux derives de la pyrazolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant, et des intermediaires
US4774243A (en) * 1985-12-24 1988-09-27 Merck & Co., Inc. Dopamine agonists for treating elevated intraocular pressure
FR2594828B1 (fr) * 1986-02-24 1988-07-01 Roussel Uclaf Derives du tetrahydrobenz (c,d) indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et intermediaires
EP0610793A1 (de) * 1993-02-08 1994-08-17 Takeda Chemical Industries, Ltd. Tetracyclische Morpholin-Derivate und ihre Verwendung als Analgetika
US6906096B2 (en) * 2002-06-28 2005-06-14 Irm Llc 4,7-Disubstituted indoles and methods of making

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds

Also Published As

Publication number Publication date
IE50515B1 (en) 1986-04-30
GR71633B (de) 1983-06-20
EP0033767B1 (de) 1984-06-27
EP0033767A1 (de) 1981-08-19
NZ195504A (en) 1984-12-14
PT72089B (en) 1982-09-02
JPH0227358B2 (de) 1990-06-15
ATE8144T1 (de) 1984-07-15
AU6459480A (en) 1981-05-28
ZA807295B (en) 1982-06-30
ES497064A0 (es) 1982-04-01
DK497580A (da) 1981-05-24
PT72089A (en) 1980-12-01
US4238486A (en) 1980-12-09
ES8203382A1 (es) 1982-04-01
IE802399L (en) 1981-05-23
JPS5687583A (en) 1981-07-16
AU539028B2 (en) 1984-09-06

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee