ZA807295B - Indolobenzoxazines - Google Patents

Indolobenzoxazines

Info

Publication number
ZA807295B
ZA807295B ZA00807295A ZA807295A ZA807295B ZA 807295 B ZA807295 B ZA 807295B ZA 00807295 A ZA00807295 A ZA 00807295A ZA 807295 A ZA807295 A ZA 807295A ZA 807295 B ZA807295 B ZA 807295B
Authority
ZA
South Africa
Prior art keywords
alkyl
indolobenzoxazines
aralkyl
halogen
novel
Prior art date
Application number
ZA00807295A
Other languages
English (en)
Inventor
James H Jones
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA807295B publication Critical patent/ZA807295B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA00807295A 1979-11-23 1980-11-21 Indolobenzoxazines ZA807295B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/096,966 US4238486A (en) 1979-11-23 1979-11-23 Indolobenzoxazines

Publications (1)

Publication Number Publication Date
ZA807295B true ZA807295B (en) 1982-06-30

Family

ID=22259990

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00807295A ZA807295B (en) 1979-11-23 1980-11-21 Indolobenzoxazines

Country Status (13)

Country Link
US (1) US4238486A (xx)
EP (1) EP0033767B1 (xx)
JP (1) JPS5687583A (xx)
AT (1) ATE8144T1 (xx)
AU (1) AU539028B2 (xx)
DE (1) DE3068379D1 (xx)
DK (1) DK497580A (xx)
ES (1) ES497064A0 (xx)
GR (1) GR71633B (xx)
IE (1) IE50515B1 (xx)
NZ (1) NZ195504A (xx)
PT (1) PT72089B (xx)
ZA (1) ZA807295B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476649A1 (fr) * 1980-02-26 1981-08-28 Roussel Uclaf Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2479830A1 (fr) * 1980-04-03 1981-10-09 Roussel Uclaf Nouveaux derives de l'indolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CA1204745A (en) * 1981-11-20 1986-05-20 Merck Co. Hexahydronaphth (1,2-b) -1,4 -oxazines
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
FR2522658A1 (fr) * 1982-03-05 1983-09-09 Roussel Uclaf Application a titre de medicaments de derives du trans 4-amino benz (c,d) indol-5-ol ainsi que de leurs sels, compositions les renfermant, nouveaux derives et leur procede de preparation
FR2526797A1 (fr) * 1982-05-12 1983-11-18 Roussel Uclaf Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
FR2533215A1 (fr) * 1982-09-20 1984-03-23 Roussel Uclaf Nouveaux derives de la c-homo 9-oxaergoline, leurs sels, procede de preparation et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
US4552956A (en) * 1984-08-15 1985-11-12 Eli Lilly And Company Partially hydrogenated pyrazolo, pyrimido and thiazolo[1,4]benzoxazines
US4587336A (en) * 1984-08-15 1986-05-06 Eli Lilly And Company Partially hydrogenated intermediate pyrazolo, pyrimido and thiazolo[1,4]benzoxazines
FR2578254B1 (fr) * 1985-03-01 1987-03-06 Roussel Uclaf Nouveaux derives de la pyrazolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant, et des intermediaires
US4774243A (en) * 1985-12-24 1988-09-27 Merck & Co., Inc. Dopamine agonists for treating elevated intraocular pressure
FR2594828B1 (fr) * 1986-02-24 1988-07-01 Roussel Uclaf Derives du tetrahydrobenz (c,d) indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et intermediaires
US5466689A (en) * 1993-02-08 1995-11-14 Takeda Chemical Industries, Ltd. Morpholine derivatives and their use
US6906096B2 (en) * 2002-06-28 2005-06-14 Irm Llc 4,7-Disubstituted indoles and methods of making

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968111A (en) * 1974-12-06 1976-07-06 Eli Lilly And Company 8,8-Disubstituted-6-methylergolines and related compounds

Also Published As

Publication number Publication date
EP0033767B1 (en) 1984-06-27
AU6459480A (en) 1981-05-28
ATE8144T1 (de) 1984-07-15
PT72089A (en) 1980-12-01
DE3068379D1 (en) 1984-08-02
NZ195504A (en) 1984-12-14
PT72089B (en) 1982-09-02
ES8203382A1 (es) 1982-04-01
US4238486A (en) 1980-12-09
IE50515B1 (en) 1986-04-30
ES497064A0 (es) 1982-04-01
IE802399L (en) 1981-05-23
EP0033767A1 (en) 1981-08-19
JPS5687583A (en) 1981-07-16
GR71633B (xx) 1983-06-20
AU539028B2 (en) 1984-09-06
DK497580A (da) 1981-05-24
JPH0227358B2 (xx) 1990-06-15

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