ES8203354A1 - Un procedimiento para la produccion de nuevos derivados heterociclicos,. - Google Patents

Un procedimiento para la produccion de nuevos derivados heterociclicos,.

Info

Publication number
ES8203354A1
ES8203354A1 ES496164A ES496164A ES8203354A1 ES 8203354 A1 ES8203354 A1 ES 8203354A1 ES 496164 A ES496164 A ES 496164A ES 496164 A ES496164 A ES 496164A ES 8203354 A1 ES8203354 A1 ES 8203354A1
Authority
ES
Spain
Prior art keywords
alkyl
aralkyl
group
alkoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES496164A
Other languages
English (en)
Other versions
ES496164A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8203354A1 publication Critical patent/ES8203354A1/es
Publication of ES496164A0 publication Critical patent/ES496164A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS HETEROCICLICOS DE FORMULA GENERAL (I). CONSISTE EN SOMETER A REACCION DE REDUCCION A UN COMPUESTO DE FORMULA GENERAL (II) EN PRESENCIA DE ALCOHOL PARA OBTENER EL COMPUESTO (I), DONDE R4 ES DISTINTO DE UN GRUPO ACILOXIALQUILO Y DEL GRUPO -N=CR10R11. OPCIONALMENTE SE HACE REACCIONAR EL COMPUESTO (I) PARA OBTENER OTRO COMPUESTO DE FORMULA GENERAL (I), EN QUE R2 REPRESENTA EL GRUPO -N=CR10R11. EL GRUPO R1R2-N-ALQ ESA UNIDO PREFERIBLEMENTE A LA POSICION 5 DEL ANILLO DE CICLOHEXADIENO; X ES PREFERENTEMENTE OXIGENO; M ES 3 O 4.
ES496164A 1979-10-22 1980-10-22 Un procedimiento para la produccion de nuevos derivados heterociclicos,. Granted ES496164A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7936544 1979-10-22
GB8027739 1980-08-27

Publications (2)

Publication Number Publication Date
ES8203354A1 true ES8203354A1 (es) 1982-04-01
ES496164A0 ES496164A0 (es) 1982-04-01

Family

ID=26273304

Family Applications (1)

Application Number Title Priority Date Filing Date
ES496164A Granted ES496164A0 (es) 1979-10-22 1980-10-22 Un procedimiento para la produccion de nuevos derivados heterociclicos,.

Country Status (7)

Country Link
US (1) US4410523A (es)
EP (1) EP0028483B1 (es)
AU (1) AU538818B2 (es)
DE (1) DE3067564D1 (es)
DK (1) DK446980A (es)
ES (1) ES496164A0 (es)
GB (1) GB2063874B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU548426B2 (en) * 1980-08-27 1985-12-12 Glaxo Group Limited 3-amino-(1,2,4)-triazoles
CA1173032A (en) * 1981-06-11 1984-08-21 Glaxo Group Limited Heterocyclic derivatives as histamine h.sub.2- antagonists
JPS5824572A (ja) * 1981-07-22 1983-02-14 グラクソ・グル−プ・リミテツド ヒスタミン受体に作用を有する化合物を含有する医薬組成物
US4571394A (en) * 1981-07-24 1986-02-18 Glaxo Group Limited Heterocyclic derivatives
BE894286A (fr) * 1981-09-04 1983-03-02 Glaxo Group Ltd Composition pharmaceutique contenant un medicament anti-inflammatoire systemique non steroidique et du 1-methyl-5-((3-(3-(1-piperidinylmethyl)phenoxy)-propyl)amino -1h-1,2,4-triazole-3-methanol ou un sel de ce compose
PT76280A (en) * 1982-02-24 1983-03-01 Glaxo Group Ltd Process for preparing heterocyclic derivatives
EP0089153B1 (en) * 1982-03-17 1986-09-24 Smith Kline & French Laboratories Limited Pyridine derivatives
US4543352A (en) * 1983-04-29 1985-09-24 William H. Rorer, Inc. Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses
US4639442A (en) * 1983-04-29 1987-01-27 William H. Rorer, Inc. Benzocyclobutene aminoalkylene ethers and thioethers, pharmaceutical compositions and use
HU191095B (en) * 1983-09-09 1987-01-28 Egyt Gyogyszervegyeszeti Gyar,Hu Process for the production of 3,5 diamino-1,2,4-triazole-derivatives
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4612309A (en) * 1984-10-23 1986-09-16 William H. Rorer, Inc. Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them
AR228941A1 (es) * 1978-04-26 1983-05-13 Glaxo Group Ltd Procedimiento para preparar nuevos derivados de 3,5-diamino-1,2,4-triazol que son activos contra receptores histaminicos
CA1159453A (en) * 1979-03-02 1983-12-27 John W. Clitherow Heterocyclic derivatives

Also Published As

Publication number Publication date
US4410523A (en) 1983-10-18
EP0028483B1 (en) 1984-04-18
AU538818B2 (en) 1984-08-30
DK446980A (da) 1981-04-23
GB2063874B (en) 1983-09-28
DE3067564D1 (en) 1984-05-24
AU6360180A (en) 1981-04-30
ES496164A0 (es) 1982-04-01
GB2063874A (en) 1981-06-10
EP0028483A1 (en) 1981-05-13

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