ES8106005A1 - Procedimiento para la obtencion de derivados de la rifamici-na-s - Google Patents

Procedimiento para la obtencion de derivados de la rifamici-na-s

Info

Publication number
ES8106005A1
ES8106005A1 ES493532A ES493532A ES8106005A1 ES 8106005 A1 ES8106005 A1 ES 8106005A1 ES 493532 A ES493532 A ES 493532A ES 493532 A ES493532 A ES 493532A ES 8106005 A1 ES8106005 A1 ES 8106005A1
Authority
ES
Spain
Prior art keywords
ansamycines
introduction
oxygen
compounds
functional group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493532A
Other languages
English (en)
Other versions
ES493532A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES493532A0 publication Critical patent/ES493532A0/es
Publication of ES8106005A1 publication Critical patent/ES8106005A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE LA RIFAMICINA-S, DE FORMULA (I), EN LA QUE R Y R'' SON ATOMOS DE HIDROGENO O R'' ES ACETILO Y R ES HIDROGENO, UN HIDROCARBILO O UN RESTO ACILO, Y DE LOS CORRESPONDIENTES DERIVADOS DE RIFAMICINA-SV. SE BASA EN LA REACCION ENTRE EL COMPUESTO DE FORMULA (II) Y EL COMPUESTO DE FORMULA ROH, O DE UNA SAL DEL MISMO, QUE CONDUCE AL INTERCAMBIO DEL BROMO POR EL GRUPO OR, DONDE R ES EL MISMO QUE EN LA FORMULA (I), SEGUIDA DE LA SEPARACION DEL PRODUCTO EN FORMA DE UN DERIVADO DE LA SERIE "S" O DE LA SERIE "SV". LA REACCION SE REALIZA EN MEDIO NEUTRO HASTA BASICO, EVENTUALMENTE, EN PRESENCIA DE UN AGENTE ACEPTOR DE ACIDO BROMHIDRICO Y/O DE UN DISOLVENTE ORGANICO, BAJO LAS CONDICIONES GENERALES CONVENCIONALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES ANTIBIOTICAS COMO ADITIVO A LOS PIENSOS Y PARA CONSERVAR LOS ALIMENTOS. *FORMULA*
ES493532A 1979-07-20 1980-07-18 Procedimiento para la obtencion de derivados de la rifamici-na-s Expired ES8106005A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH677479 1979-07-20

Publications (2)

Publication Number Publication Date
ES493532A0 ES493532A0 (es) 1981-07-01
ES8106005A1 true ES8106005A1 (es) 1981-07-01

Family

ID=4314815

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493532A Expired ES8106005A1 (es) 1979-07-20 1980-07-18 Procedimiento para la obtencion de derivados de la rifamici-na-s

Country Status (14)

Country Link
EP (1) EP0023885B1 (es)
JP (1) JPS5653683A (es)
KR (1) KR830003493A (es)
AU (1) AU6063380A (es)
DE (1) DE3069793D1 (es)
DK (1) DK312080A (es)
ES (1) ES8106005A1 (es)
FI (1) FI802256A (es)
GR (1) GR69740B (es)
IL (1) IL60618A0 (es)
NO (1) NO802177L (es)
NZ (1) NZ194380A (es)
PT (1) PT71574A (es)
ZA (1) ZA804363B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209109A1 (de) * 1981-07-21 1983-02-10 Farmitalia Carlo Erba S.p.A., 20159 Milano Verfahren zur herstellung von rifamycinderivaten und die dabei erhaltenen, neuen rifamycinderivate
JPH0558074U (ja) * 1992-01-16 1993-08-03 丸万産業株式会社 座席カバー

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1490183A (fr) * 1965-08-24 1967-07-28 Ciba Geigy Procédé de préparation de nouvelles substances dérivant de la rifamycine ayant une activité antibiotique
CH605974A5 (en) * 1973-09-28 1978-10-13 Ciba Geigy Ag 3-(4-Substd.-1-piperazinyl) rifamycin S and SV derivs
IT1053787B (it) * 1974-10-29 1981-10-10 Pastori A Macrolidi azotati e loro preparazione
US4298692A (en) * 1979-01-25 1981-11-03 Ciba-Geigy Corporation Fermentation process for producing a rifamycin derivative

Also Published As

Publication number Publication date
NZ194380A (en) 1982-09-14
GR69740B (es) 1982-07-12
DK312080A (da) 1981-01-21
IL60618A0 (en) 1980-09-16
ES493532A0 (es) 1981-07-01
EP0023885A1 (de) 1981-02-11
DE3069793D1 (en) 1985-01-24
PT71574A (de) 1980-08-01
NO802177L (no) 1981-01-21
AU6063380A (en) 1981-01-22
FI802256A (fi) 1981-01-21
EP0023885B1 (de) 1984-12-12
ZA804363B (en) 1981-07-29
JPS5653683A (en) 1981-05-13
KR830003493A (ko) 1983-06-20

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