ES8105725A1 - Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos - Google Patents

Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos

Info

Publication number
ES8105725A1
ES8105725A1 ES495008A ES495008A ES8105725A1 ES 8105725 A1 ES8105725 A1 ES 8105725A1 ES 495008 A ES495008 A ES 495008A ES 495008 A ES495008 A ES 495008A ES 8105725 A1 ES8105725 A1 ES 8105725A1
Authority
ES
Spain
Prior art keywords
same
compositions containing
producing
pharmaceutical compositions
basically substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495008A
Other languages
English (en)
Other versions
ES495008A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK
Asta Medica GmbH
Original Assignee
ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK
Asta Werke AG Chemische Fabrik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK, Asta Werke AG Chemische Fabrik filed Critical ASTA-WERKE AKTIENGESELLSCHAFT CHEMISCHE FABRIK
Publication of ES8105725A1 publication Critical patent/ES8105725A1/es
Publication of ES495008A0 publication Critical patent/ES495008A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UREAS SUSTITUIDAS CON RADICALES BASICOS DE FORMULA GENERAL (I), DONDE X SIGNIFICA UN ATOMO DE OXIGENO O EL GRUPO R4-N < , R4 SIGNIFICA EL GRUPO METILSULFONILO, EL GRUPO DIETILCARBAMOILO O EL GRUPO (IV), Y R1 SIGNIFICA UN GRUPO ALCOHILO. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II) CON UN COMPUESTO DE FORMULA GENERAL (III), DONDE X, R1, R2, R3 TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I) Y Q REPRESENTA UN ATOMO DE HALOGENO O UN GRUPO ALCOHILSULFONILOXI. LOS COMPUESTOS OBTENIDOS SON ADECUADOS EN EL TRATAMIENTO LOCAL DE ENFERMEDADES PRODUCIDAS POR VIRUS. *FORMULA*
ES495008A 1978-08-30 1980-09-12 Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos Granted ES495008A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782837794 DE2837794A1 (de) 1978-08-30 1978-08-30 Basisch substituierte harnstoffe und thioharnstoffe, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8105725A1 true ES8105725A1 (es) 1981-06-16
ES495008A0 ES495008A0 (es) 1981-06-16

Family

ID=6048245

Family Applications (3)

Application Number Title Priority Date Filing Date
ES483712A Expired ES8101062A1 (es) 1978-08-30 1979-08-29 Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos.
ES495008A Granted ES495008A0 (es) 1978-08-30 1980-09-12 Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos
ES495003A Granted ES495003A0 (es) 1978-08-30 1980-09-12 Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES483712A Expired ES8101062A1 (es) 1978-08-30 1979-08-29 Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES495003A Granted ES495003A0 (es) 1978-08-30 1980-09-12 Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos

Country Status (14)

Country Link
US (1) US4239761A (es)
EP (1) EP0008696B1 (es)
JP (1) JPS5562078A (es)
AU (1) AU522184B2 (es)
CA (1) CA1135695A (es)
DE (1) DE2837794A1 (es)
DK (1) DK361379A (es)
ES (3) ES8101062A1 (es)
FI (1) FI792650A (es)
GR (1) GR66394B (es)
IE (1) IE48816B1 (es)
MC (1) MC1276A1 (es)
NO (1) NO792790L (es)
ZA (1) ZA794173B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581454A (en) * 1983-07-18 1986-04-08 The Dow Chemical Company Adducts of aminohydrocarbyl piperzaines and urea
DE3706421A1 (de) * 1987-02-27 1988-09-08 Robugen Gmbh Arzneimittel zur behandlung viraler erkrankungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643669A1 (de) * 1967-10-04 1972-04-06 Basf Ag Antistatisches Mittel
GB1369249A (en) * 1970-08-07 1974-10-02 Pfizer Amines the preparation thereof and their use in pharmaceutical compositions
BE789830A (fr) 1971-10-09 1973-02-01 Asta Werke Ag Chem Fab Procede de preparation de nouveaux derives cycliques d'uree et de leurssels avec des acides pharmacologiquement acceptables

Also Published As

Publication number Publication date
DE2837794A1 (de) 1980-03-13
NO792790L (no) 1980-03-03
EP0008696A1 (en) 1980-03-19
IE48816B1 (en) 1985-05-29
ES8101062A1 (es) 1982-04-16
US4239761A (en) 1980-12-16
ES495008A0 (es) 1981-06-16
IE791648L (en) 1980-02-29
AU4995279A (en) 1980-03-06
MC1276A1 (fr) 1980-05-23
ES8105724A1 (es) 1981-06-16
ZA794173B (en) 1980-08-27
GR66394B (es) 1981-03-20
AU522184B2 (en) 1982-05-20
ES483712A0 (es) 1980-12-01
JPS5562078A (en) 1980-05-10
ES495003A0 (es) 1981-06-16
EP0008696B1 (en) 1982-12-15
FI792650A (fi) 1980-03-01
CA1135695A (en) 1982-11-16
DK361379A (da) 1980-03-01

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