ES8105316A1 - Procedimiento para preparar la sal de d-diamonio del anti- biotico de oxa-beta-lactama - Google Patents
Procedimiento para preparar la sal de d-diamonio del anti- biotico de oxa-beta-lactamaInfo
- Publication number
- ES8105316A1 ES8105316A1 ES491085A ES491085A ES8105316A1 ES 8105316 A1 ES8105316 A1 ES 8105316A1 ES 491085 A ES491085 A ES 491085A ES 491085 A ES491085 A ES 491085A ES 8105316 A1 ES8105316 A1 ES 8105316A1
- Authority
- ES
- Spain
- Prior art keywords
- solution
- acetone
- epimer
- antibiotic
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 8
- 239000000243 solution Substances 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 3
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 239000000908 ammonium hydroxide Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 238000004128 high performance liquid chromatography Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/035,037 US4252953A (en) | 1979-05-01 | 1979-05-01 | Antibiotic crystalline epimer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES491085A0 ES491085A0 (es) | 1981-05-16 |
| ES8105316A1 true ES8105316A1 (es) | 1981-05-16 |
Family
ID=21880235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES491085A Expired ES8105316A1 (es) | 1979-05-01 | 1980-04-30 | Procedimiento para preparar la sal de d-diamonio del anti- biotico de oxa-beta-lactama |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US4252953A (ref) |
| EP (1) | EP0018811B1 (ref) |
| JP (1) | JPS55153788A (ref) |
| KR (1) | KR840000078B1 (ref) |
| AR (1) | AR230450A1 (ref) |
| AT (1) | AT370108B (ref) |
| AU (1) | AU538283B2 (ref) |
| BE (1) | BE882980A (ref) |
| BG (1) | BG34905A3 (ref) |
| CA (1) | CA1138867A (ref) |
| CH (1) | CH646434A5 (ref) |
| CS (1) | CS226013B2 (ref) |
| DD (1) | DD150352A5 (ref) |
| DE (1) | DE3061751D1 (ref) |
| DK (1) | DK177980A (ref) |
| EG (1) | EG14719A (ref) |
| ES (1) | ES8105316A1 (ref) |
| FI (1) | FI801345A7 (ref) |
| FR (1) | FR2455605A1 (ref) |
| GB (1) | GB2047707B (ref) |
| GR (1) | GR68202B (ref) |
| HU (1) | HU184750B (ref) |
| IE (1) | IE49775B1 (ref) |
| IL (1) | IL59912A (ref) |
| IT (1) | IT1141935B (ref) |
| LU (1) | LU82411A1 (ref) |
| MY (1) | MY8500601A (ref) |
| NZ (1) | NZ193528A (ref) |
| PH (1) | PH15596A (ref) |
| PL (1) | PL125579B1 (ref) |
| PT (1) | PT71140A (ref) |
| RO (1) | RO79684A (ref) |
| SU (1) | SU860705A3 (ref) |
| ZA (1) | ZA802475B (ref) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS597193A (ja) * | 1982-07-02 | 1984-01-14 | Shionogi & Co Ltd | マロニルメチル基の異性化方法 |
| JP2007508175A (ja) * | 2003-10-08 | 2007-04-05 | ベール ゲーエムベーハー ウント コー カーゲー | 構成部品、特に車両用ハイブリッド支持体と、この種の構成部品を形成する方法と、この種の構成部品の使用 |
| WO2005035338A1 (de) * | 2003-10-08 | 2005-04-21 | Behr Gmbh & Co. Kg | Verfahren und vorrichtung zur herstellung eines bauteils, insbesondere eines hybridbaudteils für einen querträger eines fahrzeugs sowie bauteil und verwendung eines bauteils |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1085392A (en) * | 1976-03-25 | 1980-09-09 | Masayuki Narisada | Arylmalonamido-1-oxadethiacephalosporins |
| SE443143B (sv) * | 1976-03-25 | 1986-02-17 | Shionogi & Co | Forfarande for framstellning av arylmalonamido-1-oxadetiacefalosporiner |
| US4124762A (en) * | 1977-11-07 | 1978-11-07 | Yeda Research And Development Co., Ltd. | 7-[(Pyridylthiomethyl)phenyl]acetamido-cephalosporin derivatives |
| US4148997A (en) * | 1977-11-07 | 1979-04-10 | Yeda Research And Development Co., Ltd. | 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives |
| US4125715A (en) * | 1977-11-25 | 1978-11-14 | Yeda Research And Development Co. Ltd. | 7-[(Substituted-isothioureamethyl)phenyl]-acetamidocephalosporin derivatives |
-
1979
- 1979-05-01 US US06/035,037 patent/US4252953A/en not_active Expired - Lifetime
-
1980
- 1980-04-21 PH PH23927A patent/PH15596A/en unknown
- 1980-04-24 NZ NZ193528A patent/NZ193528A/xx unknown
- 1980-04-24 PT PT71140A patent/PT71140A/pt unknown
- 1980-04-24 CA CA000350600A patent/CA1138867A/en not_active Expired
- 1980-04-24 FR FR8009241A patent/FR2455605A1/fr active Granted
- 1980-04-24 ZA ZA00802475A patent/ZA802475B/xx unknown
- 1980-04-24 AT AT0220980A patent/AT370108B/de not_active IP Right Cessation
- 1980-04-24 IL IL59912A patent/IL59912A/xx not_active IP Right Cessation
- 1980-04-25 HU HU801040A patent/HU184750B/hu not_active IP Right Cessation
- 1980-04-25 FI FI801345A patent/FI801345A7/fi not_active Application Discontinuation
- 1980-04-25 JP JP5611080A patent/JPS55153788A/ja active Granted
- 1980-04-25 DK DK177980A patent/DK177980A/da not_active Application Discontinuation
- 1980-04-25 BE BE1/9799A patent/BE882980A/fr not_active IP Right Cessation
- 1980-04-25 PL PL1980223753A patent/PL125579B1/pl unknown
- 1980-04-26 RO RO80100971A patent/RO79684A/ro unknown
- 1980-04-28 EP EP80301392A patent/EP0018811B1/en not_active Expired
- 1980-04-28 DE DE8080301392T patent/DE3061751D1/de not_active Expired
- 1980-04-28 GB GB8013972A patent/GB2047707B/en not_active Expired
- 1980-04-29 GR GR61808A patent/GR68202B/el unknown
- 1980-04-29 LU LU82411A patent/LU82411A1/fr unknown
- 1980-04-29 IT IT21697/80A patent/IT1141935B/it active
- 1980-04-29 AR AR280840A patent/AR230450A1/es active
- 1980-04-29 SU SU802913905A patent/SU860705A3/ru active
- 1980-04-30 IE IE882/80A patent/IE49775B1/en not_active IP Right Cessation
- 1980-04-30 EG EG268/80A patent/EG14719A/xx active
- 1980-04-30 CS CS803045A patent/CS226013B2/cs unknown
- 1980-04-30 CH CH335480A patent/CH646434A5/fr not_active IP Right Cessation
- 1980-04-30 DD DD80220809A patent/DD150352A5/de unknown
- 1980-04-30 AU AU57914/80A patent/AU538283B2/en not_active Ceased
- 1980-04-30 BG BG047588A patent/BG34905A3/xx unknown
- 1980-04-30 ES ES491085A patent/ES8105316A1/es not_active Expired
- 1980-05-01 KR KR1019800001756A patent/KR840000078B1/ko not_active Expired
-
1985
- 1985-12-30 MY MY601/85A patent/MY8500601A/xx unknown
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