ES8102108A1 - Procedimiento para preparar una composicion antitumoral que contiene como ingrediente activo una sal del acido tiazoli- din-4-carboxilico. - Google Patents
Procedimiento para preparar una composicion antitumoral que contiene como ingrediente activo una sal del acido tiazoli- din-4-carboxilico.Info
- Publication number
- ES8102108A1 ES8102108A1 ES487052A ES487052A ES8102108A1 ES 8102108 A1 ES8102108 A1 ES 8102108A1 ES 487052 A ES487052 A ES 487052A ES 487052 A ES487052 A ES 487052A ES 8102108 A1 ES8102108 A1 ES 8102108A1
- Authority
- ES
- Spain
- Prior art keywords
- thiazolidine
- carboxylic acid
- tumors
- treatment
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION ANTITUMORAL, CUYO INGREDIENTE ACTIVO ES UNA SAL DE ACIDO TIAZOLIDIN-4-CABOXILICO, DE FORMULA (I), DONDE X ES UN CATION DE SODIO, POTASIO, CALCIO O MAGNESIO Y N ES SU VALENCIA. LAS FASES DEL PROCEDIMIENTO DE PREPARACION SON SECUENCIALMENTE LAS SIGUIENTES: NEUTRALIZACION DE UNA SOLUCION ACUOSA DEL ACIDO TIAZOLIDIN-4-CARBOXILICO CON UNA BASE EN PRESENCIA DE UN AGENTE DE LIOFILIZACION; FILTRADO, CON PROTECCION DE LA LUZ, DE LA SOLUCION RESULTANTE; LIOFILIZACION DE LA SOLUCION DE LA SAL OBTENIDA, Y ENVASADO DE DICHO POLVO EN UN VIAL. FINALMENTE PUEDE SER TRATADO PARA CONSEGUIR LA PRESENTACION FARMACEUTICA ADECUADA. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/971,729 US4384001A (en) | 1978-12-21 | 1978-12-21 | Treatment of tumors with thiazolidine-4-carboxylic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8102108A1 true ES8102108A1 (es) | 1980-12-16 |
ES487052A0 ES487052A0 (es) | 1980-12-16 |
Family
ID=25518727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487052A Granted ES487052A0 (es) | 1978-12-21 | 1979-12-19 | Procedimiento para preparar una composicion antitumoral que contiene como ingrediente activo una sal del acido tiazoli- din-4-carboxilico. |
Country Status (16)
Country | Link |
---|---|
US (1) | US4384001A (es) |
JP (1) | JPS55115822A (es) |
AU (1) | AU5390579A (es) |
BE (1) | BE880744A (es) |
CA (1) | CA1149284A (es) |
DE (1) | DE2951050A1 (es) |
DK (1) | DK542979A (es) |
ES (1) | ES487052A0 (es) |
FR (1) | FR2444459A1 (es) |
GB (1) | GB2039736B (es) |
IL (1) | IL58948A0 (es) |
IT (1) | IT1193348B (es) |
LU (1) | LU82013A1 (es) |
NL (1) | NL7909199A (es) |
SE (1) | SE7910300L (es) |
ZA (1) | ZA796918B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE53332B1 (en) * | 1980-03-14 | 1988-10-26 | Efamol Ltd | Pharmaceutical compositions |
JPS57128625A (en) * | 1981-01-30 | 1982-08-10 | Rikagaku Kenkyusho | Carcinostatic |
US4335210A (en) * | 1981-02-11 | 1982-06-15 | Cornell Research Foundation | Method of producing L-cysteine |
FR2547728B1 (fr) * | 1983-06-24 | 1986-05-02 | Riker Laboratories Inc | Medicament a base d'acide d thiazolidine carboxylique |
FR2547729B1 (fr) * | 1983-06-24 | 1986-05-02 | Riker Laboratories Inc | Medicament a base d'acide dl thiazolidine carboxylique |
JPS62501769A (ja) * | 1984-12-18 | 1987-07-16 | デイビツト ラビン | 細胞毒性アルデヒドとベニシラミンとの反応性成物を含有する抗腫瘍組成物及びその使用方法 |
JPH066578B2 (ja) * | 1985-12-27 | 1994-01-26 | 三共株式会社 | チアゾリジン誘導体 |
JPH01170063U (es) * | 1988-05-11 | 1989-11-30 | ||
JPH0467539U (es) * | 1990-10-18 | 1992-06-16 | ||
DE69214467T3 (de) * | 1991-01-10 | 2000-09-28 | Transcend Therapeutics Inc | Verwendung von L-2-oxo Thiazolidin-4-carboxylat zur Behandlung von Atemnotsyndrom |
ES2277787B1 (es) * | 2006-01-02 | 2008-06-16 | Universidad De Cadiz | Empleo de tioprolina en tratamientos de reduccion de peso corporal. |
-
1978
- 1978-12-21 US US05/971,729 patent/US4384001A/en not_active Expired - Lifetime
-
1979
- 1979-12-12 GB GB7942753A patent/GB2039736B/en not_active Expired
- 1979-12-13 IL IL58948A patent/IL58948A0/xx unknown
- 1979-12-14 SE SE7910300A patent/SE7910300L/xx unknown
- 1979-12-17 AU AU53905/79A patent/AU5390579A/en not_active Abandoned
- 1979-12-18 IT IT28170/79A patent/IT1193348B/it active
- 1979-12-19 DE DE19792951050 patent/DE2951050A1/de not_active Withdrawn
- 1979-12-19 LU LU82013A patent/LU82013A1/fr unknown
- 1979-12-19 BE BE0/198657A patent/BE880744A/fr not_active IP Right Cessation
- 1979-12-19 FR FR7931158A patent/FR2444459A1/fr active Granted
- 1979-12-19 CA CA000342263A patent/CA1149284A/en not_active Expired
- 1979-12-19 ES ES487052A patent/ES487052A0/es active Granted
- 1979-12-19 DK DK542979A patent/DK542979A/da unknown
- 1979-12-20 JP JP16495079A patent/JPS55115822A/ja active Granted
- 1979-12-20 ZA ZA00796918A patent/ZA796918B/xx unknown
- 1979-12-20 NL NL7909199A patent/NL7909199A/nl not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FR2444459B1 (es) | 1983-04-01 |
NL7909199A (nl) | 1980-06-24 |
BE880744A (fr) | 1980-06-19 |
FR2444459A1 (fr) | 1980-07-18 |
SE7910300L (sv) | 1980-06-22 |
GB2039736B (en) | 1983-04-13 |
AU5390579A (en) | 1980-06-26 |
DE2951050A1 (de) | 1980-07-10 |
IL58948A0 (en) | 1980-03-31 |
IT1193348B (it) | 1988-06-15 |
CA1149284A (en) | 1983-07-05 |
US4384001A (en) | 1983-05-17 |
ZA796918B (en) | 1980-11-26 |
IT7928170A0 (it) | 1979-12-18 |
ES487052A0 (es) | 1980-12-16 |
JPS55115822A (en) | 1980-09-06 |
JPS6328045B2 (es) | 1988-06-07 |
DK542979A (da) | 1980-06-22 |
GB2039736A (en) | 1980-08-20 |
LU82013A1 (fr) | 1981-02-03 |
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