ES557784A0 - Un procedimiento para la preparacion de fenilalquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos - Google Patents

Un procedimiento para la preparacion de fenilalquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos

Info

Publication number
ES557784A0
ES557784A0 ES557784A ES557784A ES557784A0 ES 557784 A0 ES557784 A0 ES 557784A0 ES 557784 A ES557784 A ES 557784A ES 557784 A ES557784 A ES 557784A ES 557784 A0 ES557784 A0 ES 557784A0
Authority
ES
Spain
Prior art keywords
fenilalquil
dihidrobenzopiranos
dihidrobenzofuranos
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES557784A
Other languages
English (en)
Other versions
ES8801910A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES557784A0 publication Critical patent/ES557784A0/es
Publication of ES8801910A1 publication Critical patent/ES8801910A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES557784A 1985-04-25 1987-12-15 Un procedimiento para la preparacion de fenilalquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos Expired ES8801910A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/727,317 US4713393A (en) 1985-04-25 1985-04-25 Phenylpropyl-2,3-dihydrobenzofurans useful as anti-inflammatory agents

Publications (2)

Publication Number Publication Date
ES557784A0 true ES557784A0 (es) 1988-03-01
ES8801910A1 ES8801910A1 (es) 1988-03-01

Family

ID=24922190

Family Applications (2)

Application Number Title Priority Date Filing Date
ES554335A Expired ES8802040A1 (es) 1985-04-25 1986-04-24 Un procedimiento para la preparacion de fenialquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos
ES557784A Expired ES8801910A1 (es) 1985-04-25 1987-12-15 Un procedimiento para la preparacion de fenilalquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES554335A Expired ES8802040A1 (es) 1985-04-25 1986-04-24 Un procedimiento para la preparacion de fenialquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos

Country Status (7)

Country Link
US (1) US4713393A (es)
EP (1) EP0199235B1 (es)
JP (1) JPS61251679A (es)
CA (1) CA1308416C (es)
DE (1) DE3673217D1 (es)
DK (1) DK188286A (es)
ES (2) ES8802040A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753725B2 (ja) * 1987-10-08 1995-06-07 富山化学工業株式会社 ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
US4966907A (en) * 1988-08-12 1990-10-30 Merck & Co., Inc. 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
EP0640609A1 (en) * 1993-08-24 1995-03-01 Ono Pharmaceutical Co., Ltd. Fused phenol derivatives having inhibitory activity on TXA2 synthetase, and 5-lipoxygenase and scavenging activity on oxygen species
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
EP1830186A1 (en) * 2006-03-01 2007-09-05 ETH Zürich High-throughput cell-based screening system
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
US7632119B1 (en) * 2008-08-11 2009-12-15 Cheng Uei Precision Industry Co., Ltd. Power adapter
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE650987A (es) * 1963-07-25 1965-01-25
DE2315349A1 (de) * 1973-03-28 1974-10-03 Bayer Ag Nicht verfaerbende alterungsschutzmittel
US4100294A (en) * 1976-12-06 1978-07-11 Merck & Co., Inc. 5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives
DE2803544A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue benzofuran- und benzoxepinderivate
US4189496A (en) * 1978-02-16 1980-02-19 Merck & Co., Inc. 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid
GR75101B (es) * 1980-10-23 1984-07-13 Pfizer
US4495357A (en) * 1981-07-01 1985-01-22 The Upjohn Company Pyridyl-substituted-benzofurans
US4490531A (en) * 1981-07-01 1984-12-25 The Upjohn Company Pyridyl-substituted-benzofurans
US4435422A (en) * 1982-09-15 1984-03-06 Abbott Laboratories 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions
US4537903A (en) * 1983-10-12 1985-08-27 Merck & Co., Inc. Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents

Also Published As

Publication number Publication date
EP0199235B1 (en) 1990-08-08
ES554335A0 (es) 1988-03-16
JPH0415230B2 (es) 1992-03-17
ES8802040A1 (es) 1988-03-16
DE3673217D1 (de) 1990-09-13
US4713393A (en) 1987-12-15
EP0199235A3 (en) 1987-08-05
DK188286D0 (da) 1986-04-24
JPS61251679A (ja) 1986-11-08
EP0199235A2 (en) 1986-10-29
CA1308416C (en) 1992-10-06
ES8801910A1 (es) 1988-03-01
DK188286A (da) 1986-10-26

Similar Documents

Publication Publication Date Title
ES557743A0 (es) Un procedimiento para la preparacion de nuevas piranopiridinas
ES551249A0 (es) Un procedimiento para la preparacion de peptidilaminodioles.
ES553044A0 (es) Un procedimiento para la preparacion de nuevos derivados de fenoxialquilaminopirimidina.
ES554405A0 (es) Un procedimiento para la preparacion de derivados de aza-indol.
ES556738A0 (es) Un procedimiento para la preparacion de nuevos piridazinaminas.
ES541336A0 (es) Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofen.
ES552189A0 (es) Un procedimiento para la preparacion de derivados de piridimilmidazolidiona.
ES554983A0 (es) Un procedimiento para la preparacion de silileteres.
ES524271A0 (es) Un procedimiento para la preparacion de nuevos derivados de daunorrubicina y doxorrubicina.
ES555868A0 (es) Un procedimiento para la preparacion de sulfonamidas
ES557413A0 (es) Un procedimiento para la preparacion de un polialquenoilisocianato
ES554286A0 (es) Un procedimiento para la preparacion de nuevos derivados glicopepticos
ES557784A0 (es) Un procedimiento para la preparacion de fenilalquil-2,3-dihidrobenzofuranos y los correspondientes dihidrobenzopiranos
ES557772A0 (es) Un procedimiento para la preparacion de epipodofilotoxina
ES553602A0 (es) Un procedimiento para la preparacion de nuevas quinazolindionas
ES557427A0 (es) Un procedimiento para la preparacion de tetrahidroimidazoquinazolinonas
ES553703A0 (es) Un procedimiento para la preparacion de vesiculas de fosfoliptidos.
ES551508A0 (es) Un procedimiento para la preparacion de nuevas sulfonilureas
ES553705A0 (es) Un procedimiento para la preparacion de una alcanoilanilida
ES554469A0 (es) Un procedimiento para la preparacion de derivados de mitomicina c
ES557822A0 (es) Un procedimiento para la preparacion de aminoalquil secocantinas.
ES555670A0 (es) Un procedimiento para la preparacion de hexahidroarilquinolizinas sustituidas.
ES551129A0 (es) Un procedimiento para la preparacion de nuevas 3-alcoxi-2-(n-pirrolidino)-n-pirimidinil- o n-pirazinil-propilaminas
ES556807A0 (es) Un procedimiento para la preparacion de nuevos 11-metileno-esteroides.
ES555109A0 (es) Un procedimiento para la preparacion de nuevos derivados de propanodiona.