DK188286A - Phenylalkyl-2,3-dihydrobenzofuraner og analoge heraf samt praeparater indeholdende disse forbindelser - Google Patents
Phenylalkyl-2,3-dihydrobenzofuraner og analoge heraf samt praeparater indeholdende disse forbindelser Download PDFInfo
- Publication number
- DK188286A DK188286A DK188286A DK188286A DK188286A DK 188286 A DK188286 A DK 188286A DK 188286 A DK188286 A DK 188286A DK 188286 A DK188286 A DK 188286A DK 188286 A DK188286 A DK 188286A
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- dihydrobenzofuranes
- phenylalkyl
- analogues
- preparations containing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title description 3
- 238000002360 preparation method Methods 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/727,317 US4713393A (en) | 1985-04-25 | 1985-04-25 | Phenylpropyl-2,3-dihydrobenzofurans useful as anti-inflammatory agents |
| US72731785 | 1985-04-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK188286D0 DK188286D0 (da) | 1986-04-24 |
| DK188286A true DK188286A (da) | 1986-10-26 |
Family
ID=24922190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK188286A DK188286A (da) | 1985-04-25 | 1986-04-24 | Phenylalkyl-2,3-dihydrobenzofuraner og analoge heraf samt praeparater indeholdende disse forbindelser |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4713393A (es) |
| EP (1) | EP0199235B1 (es) |
| JP (1) | JPS61251679A (es) |
| CA (1) | CA1308416C (es) |
| DE (1) | DE3673217D1 (es) |
| DK (1) | DK188286A (es) |
| ES (2) | ES8802040A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0753725B2 (ja) * | 1987-10-08 | 1995-06-07 | 富山化学工業株式会社 | ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤 |
| US4966907A (en) * | 1988-08-12 | 1990-10-30 | Merck & Co., Inc. | 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis |
| US4975457A (en) * | 1989-09-25 | 1990-12-04 | Merck & Co., Inc. | Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis |
| US5091533A (en) * | 1990-03-12 | 1992-02-25 | Merck Frosst Canada, Inc. | 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors |
| EP0640609A1 (en) * | 1993-08-24 | 1995-03-01 | Ono Pharmaceutical Co., Ltd. | Fused phenol derivatives having inhibitory activity on TXA2 synthetase, and 5-lipoxygenase and scavenging activity on oxygen species |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| EP2392258B1 (en) | 2005-04-28 | 2014-10-08 | Proteus Digital Health, Inc. | Pharma-informatics system |
| EP1830186A1 (en) * | 2006-03-01 | 2007-09-05 | ETH Zürich | High-throughput cell-based screening system |
| US8795627B2 (en) | 2007-03-21 | 2014-08-05 | Raptor Pharmaceuticals Inc. | Treatment of liver disorders by administration of RAP conjugates |
| US7632119B1 (en) * | 2008-08-11 | 2009-12-15 | Cheng Uei Precision Industry Co., Ltd. | Power adapter |
| AU2010216512B2 (en) | 2009-02-20 | 2016-06-30 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| WO2010129819A2 (en) | 2009-05-06 | 2010-11-11 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE650987A (es) * | 1963-07-25 | 1965-01-25 | ||
| DE2315349A1 (de) * | 1973-03-28 | 1974-10-03 | Bayer Ag | Nicht verfaerbende alterungsschutzmittel |
| US4100294A (en) * | 1976-12-06 | 1978-07-11 | Merck & Co., Inc. | 5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives |
| DE2803544A1 (de) * | 1978-01-27 | 1979-08-02 | Sandoz Ag | Neue benzofuran- und benzoxepinderivate |
| US4189496A (en) * | 1978-02-16 | 1980-02-19 | Merck & Co., Inc. | 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid |
| GR75101B (es) * | 1980-10-23 | 1984-07-13 | Pfizer | |
| US4490531A (en) * | 1981-07-01 | 1984-12-25 | The Upjohn Company | Pyridyl-substituted-benzofurans |
| US4495357A (en) * | 1981-07-01 | 1985-01-22 | The Upjohn Company | Pyridyl-substituted-benzofurans |
| US4435422A (en) * | 1982-09-15 | 1984-03-06 | Abbott Laboratories | 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions |
| US4537903A (en) * | 1983-10-12 | 1985-08-27 | Merck & Co., Inc. | Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents |
-
1985
- 1985-04-25 US US06/727,317 patent/US4713393A/en not_active Expired - Fee Related
-
1986
- 1986-04-14 DE DE8686105073T patent/DE3673217D1/de not_active Expired - Fee Related
- 1986-04-14 EP EP86105073A patent/EP0199235B1/en not_active Expired - Lifetime
- 1986-04-22 CA CA000507263A patent/CA1308416C/en not_active Expired - Fee Related
- 1986-04-24 DK DK188286A patent/DK188286A/da not_active Application Discontinuation
- 1986-04-24 ES ES554335A patent/ES8802040A1/es not_active Expired
- 1986-04-25 JP JP61094966A patent/JPS61251679A/ja active Granted
-
1987
- 1987-12-15 ES ES557784A patent/ES8801910A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3673217D1 (de) | 1990-09-13 |
| JPS61251679A (ja) | 1986-11-08 |
| EP0199235A3 (en) | 1987-08-05 |
| JPH0415230B2 (es) | 1992-03-17 |
| ES554335A0 (es) | 1988-03-16 |
| DK188286D0 (da) | 1986-04-24 |
| EP0199235B1 (en) | 1990-08-08 |
| US4713393A (en) | 1987-12-15 |
| ES557784A0 (es) | 1988-03-01 |
| ES8801910A1 (es) | 1988-03-01 |
| ES8802040A1 (es) | 1988-03-16 |
| CA1308416C (en) | 1992-10-06 |
| EP0199235A2 (en) | 1986-10-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |