ES550920A0 - Un procedimiento para la preparacion de fosfatidos de eter de glicol - Google Patents
Un procedimiento para la preparacion de fosfatidos de eter de glicolInfo
- Publication number
- ES550920A0 ES550920A0 ES550920A ES550920A ES550920A0 ES 550920 A0 ES550920 A0 ES 550920A0 ES 550920 A ES550920 A ES 550920A ES 550920 A ES550920 A ES 550920A ES 550920 A0 ES550920 A0 ES 550920A0
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- glycol ether
- ether phosphate
- phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910019142 PO4 Inorganic materials 0.000 title 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 title 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
- 239000010452 phosphate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/13—Saturated ethers containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/13—Saturated ethers containing hydroxy or O-metal groups
- C07C43/135—Saturated ethers containing hydroxy or O-metal groups having more than one ether bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/164—Unsaturated ethers containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH128784 | 1984-03-15 | ||
| CH49185 | 1985-02-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8703481A1 ES8703481A1 (es) | 1987-02-16 |
| ES550920A0 true ES550920A0 (es) | 1987-02-16 |
Family
ID=25684726
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541242A Expired ES8606233A1 (es) | 1984-03-15 | 1985-03-14 | Un procedimiento para la preparacion de fosfatidos de eter de glicol |
| ES550920A Expired ES8703481A1 (es) | 1984-03-15 | 1986-01-16 | Un procedimiento para la preparacion de fosfatidos de eter de glicol |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541242A Expired ES8606233A1 (es) | 1984-03-15 | 1985-03-14 | Un procedimiento para la preparacion de fosfatidos de eter de glicol |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4694084A (es) |
| EP (1) | EP0154977B1 (es) |
| AR (1) | AR241022A1 (es) |
| AU (1) | AU574440B2 (es) |
| CA (1) | CA1264162A (es) |
| DE (1) | DE3570239D1 (es) |
| DK (1) | DK117985A (es) |
| ES (2) | ES8606233A1 (es) |
| FI (1) | FI78299C (es) |
| HU (1) | HU195828B (es) |
| IL (1) | IL74540A (es) |
| MC (1) | MC1649A1 (es) |
| NO (1) | NO851006L (es) |
| NZ (1) | NZ211368A (es) |
| PH (1) | PH20750A (es) |
| PT (1) | PT80112B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1319886C (en) | 1987-02-03 | 1993-07-06 | Alberto Ferro | Mixed micelle solutions |
| EP0284395B1 (en) * | 1987-03-24 | 1993-06-23 | Nippon Chemiphar Co., Ltd. | Novel glycerol derivative and anti-hypertensive agent |
| CA2033725C (en) * | 1990-01-24 | 2001-05-29 | Folker Pittrof | Pharmaceutical and cosmetic compositions containing a salt of cholanic acid |
| FR2687314A1 (fr) * | 1992-02-18 | 1993-08-20 | Oreal | Dispersion de vesicules lipidiques, composition cosmetique et/ou pharmaceutique la contenant et procede de preparation de ladite dispersion. |
| AU2245295A (en) * | 1994-04-15 | 1995-11-10 | Hemagen/Pfc | Fluorochemical emulsions containing 1,3-dialkylglycerophosphoryl choline surfactants and methods of use |
| JP2740153B2 (ja) * | 1995-03-07 | 1998-04-15 | エフ・ホフマン−ラ ロシユ アーゲー | 混合ミセル |
| WO2003005992A1 (en) * | 2001-07-13 | 2003-01-23 | Nanocarrier Co., Ltd. | Lyophilizing composition of drug-encapsulating polymer micelle and method for preparation thereof |
| AU2002951216A0 (en) * | 2002-09-05 | 2002-09-19 | Dbl Australia Pty Ltd | Surfactants and lyotropic phases formed therefrom |
| JP2007504256A (ja) * | 2003-09-01 | 2007-03-01 | メイン・ファ−マ・インタ−ナショナル・プロプライエタリ−・リミテッド | 生物活性剤の送達のための組成物及び方法 |
| DE102005016152A1 (de) * | 2005-04-07 | 2006-10-12 | Basf Ag | Herstellung von (Co)Tensiden durch Umsetzung von Polyolen mit Olefinen |
| EP3988537A1 (en) | 2011-12-07 | 2022-04-27 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
| US10479868B2 (en) | 2014-09-04 | 2019-11-19 | Nano Precision Medical, Inc. | Polymeric stabilizing formulations |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1202370B (it) * | 1976-07-12 | 1989-02-09 | Hoffmann La Roche | Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti |
| DE2820893C2 (de) * | 1978-05-12 | 1986-02-20 | A. Nattermann & Cie GmbH, 5000 Köln | Strukturanaloga von natürlichen Phospholipiden und Verfahren zur Herstellung dieser Verbindungen |
| CA1173360A (en) * | 1979-06-22 | 1984-08-28 | Jurg Schrank | Pharmaceutical preparations |
| DE3011738A1 (de) * | 1980-03-26 | 1981-10-01 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Neue glycerin-3-phosphorsaeurehalogenalkylester |
| IL64397A0 (en) * | 1981-01-07 | 1982-02-28 | Weder Hans G | Process for the preparation of liposomal medicaments |
| US4493832A (en) * | 1981-07-03 | 1985-01-15 | Fujisawa Pharmaceutical Co., Ltd. | Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same |
| US4562179A (en) * | 1982-04-19 | 1985-12-31 | Fujisawa Pharmaceutical Co., Ltd. | Phospholipid derivatives, and pharmaceutical composition of the same |
| JPS59163389A (ja) * | 1983-03-07 | 1984-09-14 | Takeda Chem Ind Ltd | リン脂質 |
| JPS59184195A (ja) * | 1983-04-04 | 1984-10-19 | Takeda Chem Ind Ltd | グリセロ−ル誘導体 |
-
1985
- 1985-02-25 CA CA000475022A patent/CA1264162A/en not_active Expired - Fee Related
- 1985-03-07 IL IL74540A patent/IL74540A/xx unknown
- 1985-03-08 NZ NZ211368A patent/NZ211368A/xx unknown
- 1985-03-08 US US06/709,871 patent/US4694084A/en not_active Expired - Fee Related
- 1985-03-11 AU AU39710/85A patent/AU574440B2/en not_active Ceased
- 1985-03-12 EP EP85102830A patent/EP0154977B1/de not_active Expired
- 1985-03-12 DE DE8585102830T patent/DE3570239D1/de not_active Expired
- 1985-03-12 FI FI850972A patent/FI78299C/fi not_active IP Right Cessation
- 1985-03-13 HU HU85923A patent/HU195828B/hu not_active IP Right Cessation
- 1985-03-13 MC MC851758A patent/MC1649A1/xx unknown
- 1985-03-13 AR AR299731A patent/AR241022A1/es active
- 1985-03-14 NO NO851006A patent/NO851006L/no unknown
- 1985-03-14 DK DK117985A patent/DK117985A/da not_active Application Discontinuation
- 1985-03-14 ES ES541242A patent/ES8606233A1/es not_active Expired
- 1985-03-14 PT PT80112A patent/PT80112B/pt not_active IP Right Cessation
- 1985-03-14 PH PH31985A patent/PH20750A/en unknown
-
1986
- 1986-01-16 ES ES550920A patent/ES8703481A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES8606233A1 (es) | 1986-04-16 |
| AR241022A1 (es) | 1991-04-30 |
| CA1264162A (en) | 1990-01-02 |
| PT80112A (en) | 1985-04-01 |
| DE3570239D1 (en) | 1989-06-22 |
| AU574440B2 (en) | 1988-07-07 |
| AR241022A2 (es) | 1991-04-30 |
| DK117985D0 (da) | 1985-03-14 |
| FI78299C (fi) | 1989-07-10 |
| NO851006L (no) | 1985-09-16 |
| FI850972A0 (fi) | 1985-03-12 |
| HUT36824A (en) | 1985-10-28 |
| EP0154977B1 (de) | 1989-05-17 |
| AU3971085A (en) | 1985-09-19 |
| DK117985A (da) | 1985-09-16 |
| ES541242A0 (es) | 1986-04-16 |
| EP0154977A2 (de) | 1985-09-18 |
| PT80112B (en) | 1987-03-24 |
| FI78299B (fi) | 1989-03-31 |
| IL74540A0 (en) | 1985-06-30 |
| IL74540A (en) | 1989-02-28 |
| EP0154977A3 (en) | 1986-02-19 |
| HU195828B (en) | 1988-07-28 |
| PH20750A (en) | 1987-04-02 |
| US4694084A (en) | 1987-09-15 |
| FI850972L (fi) | 1985-09-16 |
| NZ211368A (en) | 1988-11-29 |
| ES8703481A1 (es) | 1987-02-16 |
| MC1649A1 (fr) | 1986-04-07 |
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