ES534170A0 - Un procedimiento para preparar 1-piridil-alquil-4-aril-piperazinas - Google Patents
Un procedimiento para preparar 1-piridil-alquil-4-aril-piperazinasInfo
- Publication number
- ES534170A0 ES534170A0 ES534170A ES534170A ES534170A0 ES 534170 A0 ES534170 A0 ES 534170A0 ES 534170 A ES534170 A ES 534170A ES 534170 A ES534170 A ES 534170A ES 534170 A0 ES534170 A0 ES 534170A0
- Authority
- ES
- Spain
- Prior art keywords
- piridil
- piperazines
- aryl
- alkyl
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48664/83A IT1200928B (it) | 1983-07-11 | 1983-07-11 | Procedimento per la preparazione di 1-piridil-alchil-4-aril piperazine utili per la loro attivita' antiipertensiva,lloro separazione nei relativi antipodi ottici e composti stereoisomeri cosi' ottenuti |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8603461A1 ES8603461A1 (es) | 1985-12-16 |
| ES534170A0 true ES534170A0 (es) | 1985-12-16 |
Family
ID=11267912
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES534170A Granted ES534170A0 (es) | 1983-07-11 | 1984-07-10 | Un procedimiento para preparar 1-piridil-alquil-4-aril-piperazinas |
| ES545191A Expired ES8606228A1 (es) | 1983-07-11 | 1985-07-15 | Un procedimiento para separar los antipodas opticos de 1-pi-ridil-alquil-4-aril-piperazinas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545191A Expired ES8606228A1 (es) | 1983-07-11 | 1985-07-15 | Un procedimiento para separar los antipodas opticos de 1-pi-ridil-alquil-4-aril-piperazinas |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US4578467A (es) |
| JP (1) | JPS6089470A (es) |
| BE (1) | BE900136A (es) |
| CA (2) | CA1256108A (es) |
| DE (2) | DE3425477A1 (es) |
| ES (2) | ES534170A0 (es) |
| FR (1) | FR2549059B1 (es) |
| GB (2) | GB2143235B (es) |
| IT (1) | IT1200928B (es) |
| NL (1) | NL8402198A (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2543139B1 (fr) * | 1983-03-22 | 1985-08-16 | Cerm Cent Europ Rech Mauvernay | Derives de (1-alcoxy 2-amino) ethyl pyridine ou pyrazine, leur preparation et leur application en therapeutique |
| IT1200928B (it) * | 1983-07-11 | 1989-01-27 | Malesci Sas | Procedimento per la preparazione di 1-piridil-alchil-4-aril piperazine utili per la loro attivita' antiipertensiva,lloro separazione nei relativi antipodi ottici e composti stereoisomeri cosi' ottenuti |
| US5364872A (en) * | 1984-04-16 | 1994-11-15 | Yamanouchi Pharmaceutical Co., Ltd. | Dihydropyridine-3,5-dicarboxylic acid ester derivatives |
| DE3431152A1 (de) * | 1984-08-24 | 1986-03-06 | Cassella Ag, 6000 Frankfurt | Verfahren zur herstellung optisch aktiver, substituierter 1,4-dihydropyridine und ihre verwendung als arzneimittel |
| US4975440A (en) * | 1984-09-28 | 1990-12-04 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Optically-active 1,4-dihydropyridine |
| GB8530602D0 (en) * | 1985-12-12 | 1986-01-22 | Fujisawa Pharmaceutical Co | Heterocyclic compounds |
| FR2635105B1 (fr) * | 1988-08-03 | 1991-01-25 | Synthelabo | Derives de piperazine et leur procede de preparation |
| US5364849A (en) * | 1989-04-22 | 1994-11-15 | John Wyeth & Brother, Limited | 1-[3 or 4-[1-[4-piperazinyl]]-2 arylpropionyl or butryl]-heterocyclic derivatives |
| US5382583A (en) * | 1989-04-22 | 1995-01-17 | John Wyeth & Brother, Limited | Piperazine derivatives |
| US5453510A (en) * | 1990-07-13 | 1995-09-26 | Burroughs Wellcome Co. | Neuromuscular blocking agents |
| JPH11106375A (ja) * | 1997-08-18 | 1999-04-20 | Pfizer Pharmaceut Inc | ブラジキニンアンタゴニストとしての光学的に活性な１，４−ジヒドロピリジン化合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3332949A (en) * | 1962-11-13 | 1967-07-25 | Sterling Drug Inc | 1-phenyl-4-[2-(2-pyridyl)-ethyl] piperazines |
| NL143925C (es) * | 1965-03-09 | |||
| IT1056055B (it) * | 1974-03-01 | 1982-01-30 | Malesci Sas Inst Farmaco Bilog | Derivati eterocicli della 4 fenil riperazina i alchil sostituita ad azione farmacologica e relativo procedimento di preparazione |
| CH624402A5 (en) * | 1974-03-01 | 1981-07-31 | Malesci Sas | Process for the preparation of novel heterocyclic derivatives of 1-alkyl-substituted 4-phenylpiperazine and use of the novel derivatives |
| US3886167A (en) * | 1974-03-06 | 1975-05-27 | Us Army | 2-Aryl-6-trifluoromethyl-4-pyridylcarbinolamine antimalarials |
| US4031108A (en) * | 1974-10-09 | 1977-06-21 | Pfizer Inc. | 2-Hydroxymethyl-3-benzyloxypyridine-6-epoxyethane |
| GB1551993A (en) * | 1976-09-21 | 1979-09-05 | Malesci Sas | Pharmacologiclly active derivatives of 1 alkyl 4-phenylpiperazines and the preparation thereof |
| DE2824764A1 (de) * | 1978-06-06 | 1979-12-20 | Hoechst Ag | Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung |
| IT1200928B (it) * | 1983-07-11 | 1989-01-27 | Malesci Sas | Procedimento per la preparazione di 1-piridil-alchil-4-aril piperazine utili per la loro attivita' antiipertensiva,lloro separazione nei relativi antipodi ottici e composti stereoisomeri cosi' ottenuti |
-
1983
- 1983-07-11 IT IT48664/83A patent/IT1200928B/it active
-
1984
- 1984-07-03 US US06/627,583 patent/US4578467A/en not_active Expired - Fee Related
- 1984-07-09 CA CA000458335A patent/CA1256108A/en not_active Expired
- 1984-07-10 GB GB08417587A patent/GB2143235B/en not_active Expired
- 1984-07-10 ES ES534170A patent/ES534170A0/es active Granted
- 1984-07-11 NL NL8402198A patent/NL8402198A/nl not_active Application Discontinuation
- 1984-07-11 JP JP59144098A patent/JPS6089470A/ja active Pending
- 1984-07-11 DE DE19843425477 patent/DE3425477A1/de active Granted
- 1984-07-11 BE BE0/213316A patent/BE900136A/fr not_active IP Right Cessation
- 1984-07-11 FR FR8411020A patent/FR2549059B1/fr not_active Expired
- 1984-07-11 DE DE3448320A patent/DE3448320C2/de not_active Expired - Fee Related
-
1985
- 1985-07-15 ES ES545191A patent/ES8606228A1/es not_active Expired
- 1985-12-11 US US06/807,714 patent/US4692525A/en not_active Expired - Fee Related
-
1986
- 1986-09-08 GB GB08621586A patent/GB2178039B/en not_active Expired
-
1988
- 1988-08-22 CA CA000575394A patent/CA1263959A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2143235B (en) | 1987-08-19 |
| ES8606228A1 (es) | 1986-04-01 |
| FR2549059A1 (fr) | 1985-01-18 |
| NL8402198A (nl) | 1985-02-01 |
| BE900136A (fr) | 1984-11-05 |
| ES545191A0 (es) | 1986-04-01 |
| GB8621586D0 (en) | 1986-10-15 |
| ES8603461A1 (es) | 1985-12-16 |
| GB8417587D0 (en) | 1984-08-15 |
| CA1263959A (en) | 1989-12-19 |
| US4578467A (en) | 1986-03-25 |
| CA1263959C (es) | 1989-12-19 |
| JPS6089470A (ja) | 1985-05-20 |
| IT8348664A0 (it) | 1983-07-11 |
| DE3425477C2 (es) | 1990-03-15 |
| DE3425477A1 (de) | 1985-01-31 |
| IT1200928B (it) | 1989-01-27 |
| GB2178039B (en) | 1987-08-19 |
| GB2178039A (en) | 1987-02-04 |
| DE3448320C2 (es) | 1991-04-11 |
| FR2549059B1 (fr) | 1987-04-17 |
| CA1256108A (en) | 1989-06-20 |
| US4692525A (en) | 1987-09-08 |
| GB2143235A (en) | 1985-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |