ES531866A0 - Un procedimiento para la preparacion de una sal basica de piroxicam - Google Patents
Un procedimiento para la preparacion de una sal basica de piroxicamInfo
- Publication number
- ES531866A0 ES531866A0 ES531866A ES531866A ES531866A0 ES 531866 A0 ES531866 A0 ES 531866A0 ES 531866 A ES531866 A ES 531866A ES 531866 A ES531866 A ES 531866A ES 531866 A0 ES531866 A0 ES 531866A0
- Authority
- ES
- Spain
- Prior art keywords
- piroxicam
- procedure
- preparation
- basic salt
- dosage forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 title abstract 5
- 229960002702 piroxicam Drugs 0.000 title abstract 5
- 150000001447 alkali salts Chemical class 0.000 title 1
- 239000002552 dosage form Substances 0.000 abstract 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical class OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48830383A | 1983-04-25 | 1983-04-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8505365A1 ES8505365A1 (es) | 1985-05-16 |
| ES531866A0 true ES531866A0 (es) | 1985-05-16 |
Family
ID=23939186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES531866A Granted ES531866A0 (es) | 1983-04-25 | 1984-04-24 | Un procedimiento para la preparacion de una sal basica de piroxicam |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0123520B1 (enExample) |
| JP (1) | JPS59205375A (enExample) |
| KR (1) | KR840008345A (enExample) |
| AT (1) | ATE36531T1 (enExample) |
| AU (1) | AU548451B2 (enExample) |
| BG (1) | BG40810A3 (enExample) |
| CA (1) | CA1213220A (enExample) |
| CS (1) | CS246078B2 (enExample) |
| DD (1) | DD219672A5 (enExample) |
| DE (1) | DE3473454D1 (enExample) |
| DK (1) | DK165168C (enExample) |
| EG (1) | EG17887A (enExample) |
| ES (1) | ES531866A0 (enExample) |
| FI (1) | FI82377C (enExample) |
| GR (1) | GR81938B (enExample) |
| GT (1) | GT198404085A (enExample) |
| HU (1) | HU194217B (enExample) |
| IE (1) | IE57327B1 (enExample) |
| IL (1) | IL71598A (enExample) |
| MX (1) | MX159889A (enExample) |
| NO (1) | NO165177C (enExample) |
| NZ (1) | NZ207930A (enExample) |
| PH (1) | PH18864A (enExample) |
| PL (1) | PL144064B1 (enExample) |
| PT (1) | PT78473B (enExample) |
| RO (1) | RO88420A (enExample) |
| YU (1) | YU44232B (enExample) |
| ZA (1) | ZA843013B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582831A (en) * | 1984-11-16 | 1986-04-15 | Pfizer Inc. | Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor |
| HU200926B (en) * | 1988-10-28 | 1990-09-28 | Egyt Gyogyszervegyeszeti Gyar | Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules |
| GB9212450D0 (en) * | 1992-06-11 | 1992-07-22 | Indena Spa | New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them |
| KR100446829B1 (ko) * | 2002-02-20 | 2004-09-04 | 한국유나이티드제약 주식회사 | 가용화된 피록시캄을 함유한 확산형 정제의 조성물 및그의 제조방법 |
| KR100791160B1 (ko) * | 2006-05-30 | 2008-01-02 | 조선대학교산학협력단 | 멜록시캄의 에탄올아민염 및 이를 함유하는 약제학적조성물 |
| JP2010083826A (ja) * | 2008-10-01 | 2010-04-15 | Nihon Generic Co Ltd | オキシカム系化合物を含む固形製剤を製造する方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN160683B (enExample) * | 1981-06-01 | 1987-07-25 | Pfizer | |
| US4434164A (en) * | 1981-06-01 | 1984-02-28 | Pfizer Inc. | Crystalline benzothiazine dioxide salts |
-
1984
- 1984-04-17 RO RO84114290A patent/RO88420A/ro unknown
- 1984-04-19 AT AT84302666T patent/ATE36531T1/de not_active IP Right Cessation
- 1984-04-19 DE DE8484302666T patent/DE3473454D1/de not_active Expired
- 1984-04-19 IE IE982/84A patent/IE57327B1/en not_active IP Right Cessation
- 1984-04-19 NZ NZ207930A patent/NZ207930A/en unknown
- 1984-04-19 AU AU27160/84A patent/AU548451B2/en not_active Ceased
- 1984-04-19 EP EP84302666A patent/EP0123520B1/en not_active Expired
- 1984-04-20 IL IL71598A patent/IL71598A/xx unknown
- 1984-04-21 EG EG255/84A patent/EG17887A/xx active
- 1984-04-23 PH PH30592A patent/PH18864A/en unknown
- 1984-04-23 PT PT78473A patent/PT78473B/pt unknown
- 1984-04-24 NO NO841611A patent/NO165177C/no unknown
- 1984-04-24 DK DK204484A patent/DK165168C/da not_active IP Right Cessation
- 1984-04-24 KR KR1019840002184A patent/KR840008345A/ko not_active Ceased
- 1984-04-24 GT GT198404085A patent/GT198404085A/es unknown
- 1984-04-24 CA CA000452660A patent/CA1213220A/en not_active Expired
- 1984-04-24 DD DD84262259A patent/DD219672A5/de not_active IP Right Cessation
- 1984-04-24 ES ES531866A patent/ES531866A0/es active Granted
- 1984-04-24 MX MX5834A patent/MX159889A/es unknown
- 1984-04-24 PL PL1984247378A patent/PL144064B1/pl unknown
- 1984-04-24 BG BG065219A patent/BG40810A3/xx unknown
- 1984-04-24 GR GR74483A patent/GR81938B/el unknown
- 1984-04-24 ZA ZA843013A patent/ZA843013B/xx unknown
- 1984-04-24 HU HU841574A patent/HU194217B/hu not_active IP Right Cessation
- 1984-04-24 CS CS843036A patent/CS246078B2/cs unknown
- 1984-04-24 YU YU724/84A patent/YU44232B/xx unknown
- 1984-04-24 FI FI841604A patent/FI82377C/fi not_active IP Right Cessation
- 1984-04-25 JP JP59083624A patent/JPS59205375A/ja active Granted
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970612 |