ES525024A0 - Un procedimiento para la preparacion de un analgesico antiinflamatorio de acido acetilsalicilico y p. acetilaminofenol. - Google Patents

Un procedimiento para la preparacion de un analgesico antiinflamatorio de acido acetilsalicilico y p. acetilaminofenol.

Info

Publication number
ES525024A0
ES525024A0 ES525024A ES525024A ES525024A0 ES 525024 A0 ES525024 A0 ES 525024A0 ES 525024 A ES525024 A ES 525024A ES 525024 A ES525024 A ES 525024A ES 525024 A0 ES525024 A0 ES 525024A0
Authority
ES
Spain
Prior art keywords
acetilsalicilico
acetilaminofenol
procedure
preparation
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES525024A
Other languages
English (en)
Spanish (es)
Other versions
ES8505816A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8505816A1 publication Critical patent/ES8505816A1/es
Publication of ES525024A0 publication Critical patent/ES525024A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/618—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate
    • A61K31/621—Salicylic acid; Derivatives thereof having the carboxyl group in position 1 esterified, e.g. salsalate having the hydroxy group in position 2 esterified, e.g. benorylate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES525024A 1982-08-20 1983-08-18 Un procedimiento para la preparacion de un analgesico antiinflamatorio de acido acetilsalicilico y p. acetilaminofenol. Granted ES525024A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/410,167 US4507276A (en) 1982-08-20 1982-08-20 Analgesic capsule

Publications (2)

Publication Number Publication Date
ES8505816A1 ES8505816A1 (es) 1985-06-16
ES525024A0 true ES525024A0 (es) 1985-06-16

Family

ID=23623521

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525024A Granted ES525024A0 (es) 1982-08-20 1983-08-18 Un procedimiento para la preparacion de un analgesico antiinflamatorio de acido acetilsalicilico y p. acetilaminofenol.

Country Status (10)

Country Link
US (1) US4507276A (Sortimente)
EP (1) EP0103991A3 (Sortimente)
JP (1) JPS5989624A (Sortimente)
KR (1) KR880002673B1 (Sortimente)
AU (1) AU545179B2 (Sortimente)
CA (1) CA1209474A (Sortimente)
ES (1) ES525024A0 (Sortimente)
GR (1) GR78913B (Sortimente)
NZ (1) NZ204856A (Sortimente)
ZA (1) ZA835033B (Sortimente)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0713012B2 (ja) * 1984-02-08 1995-02-15 ア−ル ピ− シ−ラ− コ−ポレ−シヨン アセトアミノフェン・ゼラチンカプセル
US5229132A (en) * 1985-02-22 1993-07-20 Grimberg Georges Serge Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time
US5019302A (en) * 1986-03-12 1991-05-28 Washington University Technology Associates, Inc. Method for granulation
US4971805A (en) * 1987-12-23 1990-11-20 Teysan Pharmaceuticals Co., Ltd. Slow-releasing granules and long acting mixed granules comprising the same
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
IE64128B1 (en) * 1990-02-26 1995-07-12 Byrne Rynne Holdings Ltd A pharmaceutical composition
ATE158180T1 (de) * 1991-06-21 1997-10-15 Univ Cincinnati Oral verabreichbare therapeutische proteine und herstellungsverfahren
US6613332B1 (en) 1991-06-21 2003-09-02 The University Of Cincinnati Oral administration of therapeutic proteins
SG52402A1 (en) * 1992-12-22 1998-09-28 Univ Cincinnati Oral administration of immunologically active biomolecules and other therapeutic proteins
JPH0668856U (ja) * 1993-03-17 1994-09-27 公一 入澤 ミシン目入りカレンダー
US6787164B2 (en) * 2000-02-23 2004-09-07 Bioselect Innovations, Inc. Composition and method for treating the effects of diseases and maladies
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
MXPA04006608A (es) * 2002-01-07 2004-10-04 Pharmacia Corp Tratamiento de dolor, inflamacion y trastornos relacionados con inflamacion con una combinacion de inhibidor selectivo de ciclooxigenasa-2 y aspirina.
KR20050005437A (ko) 2002-04-09 2005-01-13 플라멜 테크놀로지스 아목시실린의 변형 방출을 위한 마이크로캡슐 수성 현탁액형태의 경구 제약학적 제제
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
CA2537477C (en) * 2003-09-03 2013-05-14 Boehringer Ingelheim International Gmbh Capsules containing active substance pellets with different release profiles
US20050282756A1 (en) * 2004-06-18 2005-12-22 Mehta Nozer M Oral delivery of peptide pharmaceutical compositions
US8057820B2 (en) * 2004-10-08 2011-11-15 Mcneil-Ppc, Inc. Enteric coated aspirin granules comingled with binder
ATE480229T1 (de) * 2005-05-24 2010-09-15 Flamel Tech Sa Orale pharmazeutische zusammensetzung zur behandlung einer cox-2-vermittelten erkrankung
EP1726301A1 (en) * 2005-05-24 2006-11-29 Flamel Technologies Oral pharmaceutical composition for treating a COX-2 mediated condition
JP5467870B2 (ja) 2007-02-09 2014-04-09 アルファファーム ピーティーワイ リミテッド 異なる物理的形態の２種以上の有効医薬成分を含有する投薬形態
CA2919892C (en) 2013-08-12 2019-06-18 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
WO2015095391A1 (en) 2013-12-17 2015-06-25 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
EP3169315B1 (en) 2014-07-17 2020-06-24 Pharmaceutical Manufacturing Research Services, Inc. Immediate release abuse deterrent liquid fill dosage form
AU2015336065A1 (en) 2014-10-20 2017-05-04 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
CN106389339B (zh) * 2015-08-12 2020-08-04 北京科信必成医药科技发展有限公司 一种阿司匹林无水吞服掩味颗粒及其制备方法
CN110711196B (zh) * 2018-07-12 2023-11-14 北京恒润泰生医药科技有限公司 阿司匹林和对乙酰氨基酚的分子复合物,其制备,活性及应用
WO2021011538A1 (en) * 2019-07-15 2021-01-21 R.P. Scherer Technologies, Llc Capsule dosage forms, methods of preparation and methods of use thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155590A (en) * 1962-08-02 1964-11-03 Ncr Co Encapsulation process and its product
BE640616A (Sortimente) * 1962-12-19
US3341416A (en) * 1963-12-11 1967-09-12 Ncr Co Encapsulation of aspirin in ethylcellulose and its product
US3400185A (en) * 1965-04-08 1968-09-03 Bristol Myers Co Agglomeration of smaller pharmaceutical particles into larger microspherules and enteic-coating thereof
FR5788M (Sortimente) * 1965-11-18 1968-03-18
US3488418A (en) * 1965-11-18 1970-01-06 Sterling Drug Inc Sustained relief analgesic composition
GB1276089A (en) * 1968-08-23 1972-06-01 Pfizer Ltd Pharmaceutical preparations
US3703576A (en) * 1969-08-08 1972-11-21 Fuji Photo Film Co Ltd Method of producing micro-capsules enclosing acetylsalicylic acid therein
BE759520A (fr) * 1969-11-28 1971-04-30 Aspro Nicholas Ltd Compositions d'aspirine
US3887700A (en) * 1969-11-28 1975-06-03 Aspro Nicholas Ltd Analgesic formulations
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
JPS523342B2 (Sortimente) * 1972-01-26 1977-01-27
US3859431A (en) * 1973-01-04 1975-01-07 Lilly Industries Ltd Drug formulations
US4049803A (en) * 1976-04-26 1977-09-20 Bristol-Myers Company Augmentation of blood levels of aspirin
US4294819A (en) * 1980-08-18 1981-10-13 Bristol-Myers Company Alkaline analgesic capsule
US4339428A (en) * 1980-08-18 1982-07-13 Bristol-Myers Company Capsule product containing high dosage of aspirin in powder or granulated form and alkaline tablet or pellet comprising magnesium carbonate, calcium carbonate and a magnesium dry component
DE3039073A1 (de) * 1980-10-16 1982-05-19 Röhm GmbH, 6100 Darmstadt Umhuelltes acetylsalicylsaeurepraeparat

Also Published As

Publication number Publication date
AU545179B2 (en) 1985-07-04
ES8505816A1 (es) 1985-06-16
NZ204856A (en) 1986-06-11
GR78913B (Sortimente) 1984-10-02
US4507276A (en) 1985-03-26
EP0103991A3 (en) 1985-05-22
KR880002673B1 (ko) 1988-12-20
AU1673783A (en) 1984-02-23
CA1209474A (en) 1986-08-12
EP0103991A2 (en) 1984-03-28
JPS5989624A (ja) 1984-05-23
ZA835033B (en) 1984-05-30
KR840005662A (ko) 1984-11-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203