ES493931A0 - Procedimiento de preparacion de nuevos derivados de la 3,4,5-trimetoxi-cinamoil-piperazina - Google Patents
Procedimiento de preparacion de nuevos derivados de la 3,4,5-trimetoxi-cinamoil-piperazinaInfo
- Publication number
- ES493931A0 ES493931A0 ES493931A ES493931A ES493931A0 ES 493931 A0 ES493931 A0 ES 493931A0 ES 493931 A ES493931 A ES 493931A ES 493931 A ES493931 A ES 493931A ES 493931 A0 ES493931 A0 ES 493931A0
- Authority
- ES
- Spain
- Prior art keywords
- trimetoxi
- cinamoil
- piperazine
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7919990A FR2462432A2 (fr) | 1979-08-03 | 1979-08-03 | Nouveaux derives de la 3,4,5 trimethoxy cinnamoyle piperazine, leur procede de preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8107195A1 ES8107195A1 (es) | 1981-10-01 |
| ES493931A0 true ES493931A0 (es) | 1981-10-01 |
Family
ID=9228620
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493931A Granted ES493931A0 (es) | 1979-08-03 | 1980-08-01 | Procedimiento de preparacion de nuevos derivados de la 3,4,5-trimetoxi-cinamoil-piperazina |
| ES499814A Granted ES499814A0 (es) | 1979-08-03 | 1981-02-26 | Un procedimiento de preparacion de ((metil-3)-n-butiloxicar-bonil-8-benzodioxan-1,4-il)-oxi-3-((trimetoxi-3,4,5-cinamo- il)-4-piperazin-1-il)-1-propanol-2 (s(-)) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES499814A Granted ES499814A0 (es) | 1979-08-03 | 1981-02-26 | Un procedimiento de preparacion de ((metil-3)-n-butiloxicar-bonil-8-benzodioxan-1,4-il)-oxi-3-((trimetoxi-3,4,5-cinamo- il)-4-piperazin-1-il)-1-propanol-2 (s(-)) |
Country Status (14)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2507604A2 (fr) * | 1977-04-19 | 1982-12-17 | Delalande Sa | Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique |
| US4558129A (en) * | 1983-05-18 | 1985-12-10 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade |
| US4499100A (en) * | 1983-05-18 | 1985-02-12 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade |
| US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
| US4997836A (en) * | 1988-11-11 | 1991-03-05 | Takeda Chemical Industries, Ltd. | Trisubstituted piperazine compounds, their production and use |
| US6514996B2 (en) | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
| EP0943613A4 (en) * | 1996-11-19 | 2002-07-10 | Kyowa Hakko Kogyo Kk | Oxygenic heterocyclic compounds |
| US8614233B2 (en) | 2007-05-29 | 2013-12-24 | Universite De Montreal | Cinnamoyl inhibitors of transglutaminase |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2387971A1 (fr) * | 1977-04-19 | 1978-11-17 | Delalande Sa | Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique |
-
1979
- 1979-08-03 FR FR7919990A patent/FR2462432A2/fr active Granted
-
1980
- 1980-07-18 CH CH551180A patent/CH646694A5/fr not_active IP Right Cessation
- 1980-07-21 CA CA000356675A patent/CA1155121A/en not_active Expired
- 1980-07-22 SE SE8005300A patent/SE8005300L/xx not_active Application Discontinuation
- 1980-07-28 GR GR62561A patent/GR68073B/el unknown
- 1980-07-30 DE DE19803028912 patent/DE3028912A1/de not_active Ceased
- 1980-08-01 ZA ZA00804709A patent/ZA804709B/xx unknown
- 1980-08-01 JP JP10632080A patent/JPS5626885A/ja active Granted
- 1980-08-01 AU AU61003/80A patent/AU6100380A/en not_active Abandoned
- 1980-08-01 BE BE0/201625A patent/BE884602R/fr not_active IP Right Cessation
- 1980-08-01 LU LU82677A patent/LU82677A1/fr unknown
- 1980-08-01 GB GB8025200A patent/GB2057433B/en not_active Expired
- 1980-08-01 ES ES493931A patent/ES493931A0/es active Granted
- 1980-08-04 NL NL8004434A patent/NL8004434A/nl not_active Application Discontinuation
-
1981
- 1981-02-26 ES ES499814A patent/ES499814A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8107195A1 (es) | 1981-10-01 |
| SE8005300L (sv) | 1981-02-04 |
| GB2057433B (en) | 1983-08-10 |
| CH646694A5 (fr) | 1984-12-14 |
| JPS5626885A (en) | 1981-03-16 |
| GB2057433A (en) | 1981-04-01 |
| AU6100380A (en) | 1981-02-05 |
| FR2462432B2 (enrdf_load_stackoverflow) | 1983-05-27 |
| ES8301944A1 (es) | 1982-12-16 |
| DE3028912A1 (de) | 1981-09-24 |
| ES499814A0 (es) | 1982-12-16 |
| FR2462432A2 (fr) | 1981-02-13 |
| GR68073B (enrdf_load_stackoverflow) | 1981-10-29 |
| CA1155121A (en) | 1983-10-11 |
| BE884602R (fr) | 1981-02-02 |
| ZA804709B (en) | 1981-10-28 |
| NL8004434A (nl) | 1981-02-05 |
| LU82677A1 (fr) | 1982-05-10 |
| JPS634827B2 (enrdf_load_stackoverflow) | 1988-02-01 |
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