AR219560A1 - Procedimiento para la preparacion de derivados de 5,5-dimetil-hidantoina - Google Patents

Procedimiento para la preparacion de derivados de 5,5-dimetil-hidantoina

Info

Publication number
AR219560A1
AR219560A1 AR274243A AR27424378A AR219560A1 AR 219560 A1 AR219560 A1 AR 219560A1 AR 274243 A AR274243 A AR 274243A AR 27424378 A AR27424378 A AR 27424378A AR 219560 A1 AR219560 A1 AR 219560A1
Authority
AR
Argentina
Prior art keywords
dimethyl
procedure
preparation
hydantoine
derivatives
Prior art date
Application number
AR274243A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH546578A external-priority patent/CH642944A5/de
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of AR219560A1 publication Critical patent/AR219560A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
AR274243A 1977-10-28 1978-10-26 Procedimiento para la preparacion de derivados de 5,5-dimetil-hidantoina AR219560A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
LU78407 1977-10-28
CH546578A CH642944A5 (en) 1978-05-19 1978-05-19 Urea derivatives
CH936778 1978-09-06

Publications (1)

Publication Number Publication Date
AR219560A1 true AR219560A1 (es) 1980-08-29

Family

ID=27175218

Family Applications (2)

Application Number Title Priority Date Filing Date
AR274243A AR219560A1 (es) 1977-10-28 1978-10-26 Procedimiento para la preparacion de derivados de 5,5-dimetil-hidantoina
AR278316A AR220004A1 (es) 1977-10-28 1979-10-02 Procedimiento para la preparacion de derivados de 4,4-dimetil-2-imidazolidinona

Family Applications After (1)

Application Number Title Priority Date Filing Date
AR278316A AR220004A1 (es) 1977-10-28 1979-10-02 Procedimiento para la preparacion de derivados de 4,4-dimetil-2-imidazolidinona

Country Status (26)

Country Link
US (2) US4407814A (es)
EP (1) EP0001813B1 (es)
JP (1) JPS5470271A (es)
AR (2) AR219560A1 (es)
AT (2) AT366374B (es)
AU (1) AU522536B2 (es)
BR (1) BR7807097A (es)
CA (1) CA1107744A (es)
CU (1) CU34980A (es)
DE (2) DE2861289D1 (es)
DK (1) DK481678A (es)
ES (3) ES474592A1 (es)
FI (1) FI68618C (es)
FR (1) FR2422643A1 (es)
GB (1) GB2008102B (es)
GR (1) GR70681B (es)
IE (1) IE47962B1 (es)
IL (1) IL55773A (es)
IT (1) IT1099450B (es)
MC (1) MC1220A1 (es)
NL (1) NL7810563A (es)
NO (1) NO151461C (es)
NZ (1) NZ188721A (es)
PH (1) PH13569A (es)
PT (1) PT68705A (es)
SE (1) SE7811194L (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI801184A (fi) * 1979-04-24 1980-10-25 Hoffmann La Roche Foerfarande foer framstaellning av imidazolidinderivat
DE2933917A1 (de) * 1979-08-22 1981-03-26 Basf Ag, 67063 Ludwigshafen 5-imino-imidazolidin-2-one und diese enthaltende herbizide.
DE3134933A1 (de) * 1981-09-03 1983-03-31 Hoechst Ag, 6230 Frankfurt "harnstoffderivate, verfahren zu ihrer herstellung und diese enthaltende medikamente sowie deren verwendung"
DE3382406D1 (de) * 1982-04-08 1991-10-17 Shell Int Research Neue hydantoine, ihre herstellung und verwendung.
US5112983A (en) * 1987-09-28 1992-05-12 Olin Corporation Process for producing 1,2,4-triazol-5-one using organic sulfonic acids and polymers thereof as a catalyst
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2693461B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
FR2671348B1 (fr) * 1991-01-09 1993-03-26 Roussel Uclaf Nouvelles phenylimidazolidines, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
USRE35956E (en) * 1991-01-09 1998-11-10 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
FR2724169B1 (fr) * 1994-09-06 1997-01-03 Roussel Uclaf Nouvelles phenylimidazolidines eventuellement substituees, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2715402B1 (fr) * 1994-01-05 1996-10-04 Roussel Uclaf Nouvelles phénylimidazolines éventuellement substituées, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
TW521073B (en) * 1994-01-05 2003-02-21 Hoechst Marion Roussel Inc New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them
FR2741346B1 (fr) * 1995-11-16 1997-12-19 Roussel Uclaf Nouveau procede de preparation de derives phenylimidazolidine
FR2741342B1 (fr) * 1995-11-22 1998-02-06 Roussel Uclaf Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
EP1299094A2 (en) * 2000-06-28 2003-04-09 Bristol-Myers Squibb Company Selective androgen receptor modulators and methods for their identification, design and use
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP2299266A1 (en) * 2003-12-19 2011-03-23 The Regents of the University of California Methods and materials for assessing prostate cancer therapies
NZ550102A (en) * 2004-02-24 2010-10-29 Univ California Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives)
US7709517B2 (en) * 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
ES2863798T3 (es) 2006-03-27 2021-10-11 Univ California Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos
RU2449993C2 (ru) * 2006-03-29 2012-05-10 Те Риджентс Оф Те Юниверсити Оф Калифорния Диарилтиогидантоиновые соединения
CA2703635C (en) 2007-10-26 2017-06-27 Michael E. Jung Diarylhydantoin compounds as androgen receptor modulators
EP3124481B1 (en) 2010-02-16 2018-03-28 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
KR20210013342A (ko) 2012-09-26 2021-02-03 아라곤 파마슈티컬스, 인코포레이티드 비전이성 거세 저항성 전립선암 치료용 항안드로겐
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
JOP20200076A1 (ar) 2017-10-16 2020-04-30 Aragon Pharmaceuticals Inc مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629779A (es) *
US3134663A (en) * 1957-07-23 1964-05-26 Geigy Chem Corp Herbicidal composition and method employing hydantoins
FR1405725A (fr) * 1963-08-23 1965-07-09 Shell Int Research Procédé de préparation de la 5, 5-diméthyl-4-iminohydantoine
NO124370B (es) * 1968-03-28 1972-04-10 Ciba Geigy Ag
US3690863A (en) * 1968-04-19 1972-09-12 Du Pont Esters of 3-(carboxyamino)-and 3-(thiocarboxyamino)-2-substituted crotonamides andtheir use as herbicides
DK123717B (da) * 1968-11-25 1972-07-24 Sumitomo Chemical Co 3-(3',5'-Dihalogenphenyl)-imidazolidin-2,4-dionderivater med mirobicid virkning.
JPS4916937B1 (es) * 1970-01-21 1974-04-25
US3676456A (en) * 1970-02-27 1972-07-11 Ciba Geigy Corp Derivatives of 3-aryl-5-alkylhydantoins
JPS5136332B1 (es) * 1970-12-09 1976-10-07
US4044021A (en) * 1971-10-21 1977-08-23 American Cyanamid Company Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism
IL45459A (en) * 1973-09-03 1978-01-31 Ciba Geigy Ag 1-(dichlorofluoromethylthio)-3-phenyl-imidazolidine-2,4-dione derivatives their preparation and their use as bactericides and fungicides
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
JPS5315373A (en) * 1976-07-29 1978-02-13 Mitsubishi Chem Ind Ltd Hydantoin derivatives and fungicides containing same for agriculture and horiticulture
CA1138334A (en) * 1977-10-28 1982-12-28 Karl Bernauer Pharmaceutical preparations containing certain urea derivatives
US4358606A (en) * 1981-06-19 1982-11-09 Zoecon Corporation Esters of phenalkyloxycarbonylamino acids

Also Published As

Publication number Publication date
FR2422643B1 (es) 1982-10-29
EP0001813A1 (de) 1979-05-16
IL55773A (en) 1982-02-28
AT366671B (de) 1982-04-26
ES480109A1 (es) 1980-04-01
US4407814A (en) 1983-10-04
NL7810563A (nl) 1979-05-02
DK481678A (da) 1979-04-29
FI68618B (fi) 1985-06-28
IE782130L (en) 1979-04-28
NO151461C (no) 1985-04-17
ES474592A1 (es) 1980-04-01
FI783170A (fi) 1979-04-29
ES480114A1 (es) 1980-04-01
CA1107744A (en) 1981-08-25
NO783642L (no) 1979-05-02
DE2861289D1 (en) 1982-01-14
AR220004A1 (es) 1980-09-30
GB2008102B (en) 1982-07-07
AU522536B2 (en) 1982-06-10
MC1220A1 (fr) 1979-07-20
AU4096178A (en) 1980-05-01
GB2008102A (en) 1979-05-31
PH13569A (en) 1980-06-26
DE2846946A1 (de) 1979-05-03
AT366374B (de) 1982-04-13
CU34980A (es) 1981-12-04
NO151461B (no) 1985-01-02
EP0001813B1 (de) 1981-11-04
FR2422643A1 (fr) 1979-11-09
JPS625145B2 (es) 1987-02-03
FI68618C (fi) 1985-10-10
BR7807097A (pt) 1979-05-08
US4482739A (en) 1984-11-13
ATA18281A (de) 1981-09-15
SE7811194L (sv) 1979-04-29
NZ188721A (en) 1984-11-09
GR70681B (es) 1982-12-20
IT1099450B (it) 1985-09-18
JPS5470271A (en) 1979-06-05
IL55773A0 (en) 1978-12-17
IT7829040A0 (it) 1978-10-24
IE47962B1 (en) 1984-08-08
ATA768978A (de) 1981-08-15
PT68705A (en) 1978-11-01

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