ES484380A1 - Un procedimiento no catalitico para la preparacion de deri- vados de cefalosporina - Google Patents

Un procedimiento no catalitico para la preparacion de deri- vados de cefalosporina

Info

Publication number
ES484380A1
ES484380A1 ES484380A ES484380A ES484380A1 ES 484380 A1 ES484380 A1 ES 484380A1 ES 484380 A ES484380 A ES 484380A ES 484380 A ES484380 A ES 484380A ES 484380 A1 ES484380 A1 ES 484380A1
Authority
ES
Spain
Prior art keywords
acylamino
amino
prepared
water
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES484380A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES484380A1 publication Critical patent/ES484380A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Un procedimiento no catalítico para la preparación de un derivado de cafalosporina de fórmula (I) **fórmula** donde R representa un átomo de hidrógeno o un grupo acilo, R1 representa un grupo heterocíclico sustituido o no sustituido o el grupo **fórmula** y X representa un átomo de hidrógeno o un grupo alcoxi o un carboxil derivado del mismo, cuyo procedimiento consiste en hacer reaccionar un compuesto de cefalosporina de fórmula (II)**fórmula** donde R y X son los definidos anteriormente o un carboxil derivado del mismo, con un tiol de fórmula (III) R1SH (III) donde R1 es el definido anteriormente , caracterizado porque la reacción se lleva a cabo en condiciones tales que el agua, caso de hallarse presente no pasa de cinco veces el peso de dicho compuesto de fórmula (II)
ES484380A 1978-09-22 1979-09-21 Un procedimiento no catalitico para la preparacion de deri- vados de cefalosporina Expired ES484380A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11689878A JPS5543043A (en) 1978-09-22 1978-09-22 Preparation of 3-substituted thiomethylcephalosporin derivative

Publications (1)

Publication Number Publication Date
ES484380A1 true ES484380A1 (es) 1980-10-01

Family

ID=14698365

Family Applications (1)

Application Number Title Priority Date Filing Date
ES484380A Expired ES484380A1 (es) 1978-09-22 1979-09-21 Un procedimiento no catalitico para la preparacion de deri- vados de cefalosporina

Country Status (4)

Country Link
US (1) US4564676A (es)
JP (1) JPS5543043A (es)
ES (1) ES484380A1 (es)
IT (1) IT1119169B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58113301A (ja) * 1981-12-28 1983-07-06 Shinku Yakin Kk 金属超微粒子の徐酸化装置
JPH0613530B2 (ja) * 1984-06-08 1994-02-23 武田薬品工業株式会社 セフエム化合物
JPH03124704U (es) * 1990-03-27 1991-12-17
JPH0454806A (ja) * 1990-06-22 1992-02-21 Kajima Corp 電気配電方式とそのユニット
JPH0439003U (es) * 1990-07-31 1992-04-02
JPH0622334U (ja) * 1992-05-25 1994-03-22 株式会社日本健康増進研究会 プラスター
JP3024452U (ja) * 1995-11-09 1996-05-21 株式会社正興電機製作所 ユニット式分電盤

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3840531A (en) * 1972-03-21 1974-10-08 Lilly Co Eli Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof
DK635474A (es) * 1974-02-05 1975-10-13 Ciba Geigy Ag
US4165429A (en) * 1976-06-28 1979-08-21 Yamanouchi Pharmaceutical Co., Ltd. 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES
GB1565941A (en) * 1977-02-08 1980-04-23 Toyama Chemical Co Ltd Process for producing 7-(substituted)amino-3-substituted thiomethyl cephem carboxylic acids
PT67732A (en) * 1977-03-07 1978-04-01 Lilly Co Eli Process for preparing cephalosporin compounds
US4144391A (en) * 1977-03-07 1979-03-13 Eli Lilly And Company Cephalosporin displacement reaction
JPS6027677B2 (ja) * 1978-07-06 1985-06-29 富山化学工業株式会社 ７−置換又は非置換アミノ−３−置換チオメチルセフエムカルボン酸類の新規製造法

Also Published As

Publication number Publication date
IT7968851A0 (it) 1979-09-21
IT1119169B (it) 1986-03-03
US4564676A (en) 1986-01-14
JPS5543043A (en) 1980-03-26
JPS6310707B2 (es) 1988-03-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519