ES8703401A1 - Procedimiento para la obtencion de esteres del acido 4-aci- loxi-3-oxo-butirico - Google Patents
Procedimiento para la obtencion de esteres del acido 4-aci- loxi-3-oxo-butiricoInfo
- Publication number
- ES8703401A1 ES8703401A1 ES549357A ES549357A ES8703401A1 ES 8703401 A1 ES8703401 A1 ES 8703401A1 ES 549357 A ES549357 A ES 549357A ES 549357 A ES549357 A ES 549357A ES 8703401 A1 ES8703401 A1 ES 8703401A1
- Authority
- ES
- Spain
- Prior art keywords
- acyloxy
- preparation
- butyric acid
- keto
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ESTERES DEL ACIDO 4-ACILOXI-3-OXO-BUTIRICO, DE FORMULA (I). COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA R1-OOC-CH2.COCH2X CON ACIDOS CARBOXILICOS DE FORMULA R2COOH PARA FORMAR UN COMPUESTO DE FORMULA (I) EN LAS QUE R1 REPRESENTA ALQUILO C1-4, R2 ES ALQUILO SUSTITUIDO O SIN SUSTITUIR C1-4 O ARILO Y X ES CLORO O BROMO. LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN ACEPTOR DE ACIDO, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 170JC. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS PARA LA OBTENCION DE 1,4-DIHIDROPIRIDINAS CON ANILLO LACTONA EN LA POSICION 2 Y 3.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843443678 DE3443678A1 (de) | 1984-11-30 | 1984-11-30 | Verfahren zur herstellung von 4-acyloxy-3-oxo-buttersaeureestern |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8703401A1 true ES8703401A1 (es) | 1987-02-16 |
| ES549357A0 ES549357A0 (es) | 1987-02-16 |
Family
ID=6251547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES549357A Expired ES8703401A1 (es) | 1984-11-30 | 1985-11-28 | Procedimiento para la obtencion de esteres del acido 4-aci- loxi-3-oxo-butirico |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4720572A (es) |
| EP (1) | EP0183149B1 (es) |
| JP (1) | JPS61134351A (es) |
| KR (1) | KR860004004A (es) |
| AT (1) | ATE35130T1 (es) |
| DE (1) | DE3443678A1 (es) |
| ES (1) | ES8703401A1 (es) |
| HU (1) | HU194154B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4916209A (en) * | 1987-12-23 | 1990-04-10 | Pfizer Inc. | Bioabsorbable polydepsipeptide, preparation and use thereof |
| DE4430092A1 (de) * | 1994-08-25 | 1996-02-29 | Bayer Ag | 2,3-Cyclisch kondensierte 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| ES2426609T3 (es) | 2009-02-18 | 2013-10-24 | Bayer Intellectual Property Gmbh | Derivados de 1,4-dihidropiridina sustituidos con indazol bi- y tricíclicos y usos de los mismos |
| CN101941941B (zh) * | 2009-07-06 | 2012-09-12 | 中国中化股份有限公司 | 一种羧酸酯类化合物及其用途 |
| CN110372532B (zh) * | 2018-04-12 | 2022-11-29 | 江苏瑞科医药科技有限公司 | 六氢呋喃并呋喃醇衍生物的制备方法、其中间体及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2376033A (en) * | 1942-05-08 | 1945-05-15 | Wingfoot Corp | Keto esters |
| DE2024948A1 (en) * | 1969-06-25 | 1971-01-07 | VEB Leuna Werke Walter Ulbricht, χ 4220 Leuna | Prepn of carboxylic acid esters from an - amine a halogenated hydrocarbon and |
| US3998815A (en) * | 1974-06-24 | 1976-12-21 | Interx Research Corporation | 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts |
| US4335251A (en) * | 1976-12-08 | 1982-06-15 | Hisamitsu Pharmaceutical Co. Inc. | Phenyl-i-propionic acid esters and pharmaceutical use thereof |
| DE3263545D1 (en) * | 1981-10-01 | 1985-06-20 | Lonza Ag | Process for the preparation of 4-alkoxy-acetoacetic-acid esters |
-
1984
- 1984-11-30 DE DE19843443678 patent/DE3443678A1/de not_active Withdrawn
-
1985
- 1985-11-15 US US06/798,526 patent/US4720572A/en not_active Expired - Fee Related
- 1985-11-16 EP EP85114566A patent/EP0183149B1/de not_active Expired
- 1985-11-16 AT AT85114566T patent/ATE35130T1/de not_active IP Right Cessation
- 1985-11-27 JP JP60265157A patent/JPS61134351A/ja active Pending
- 1985-11-28 ES ES549357A patent/ES8703401A1/es not_active Expired
- 1985-11-29 KR KR1019850008956A patent/KR860004004A/ko not_active Application Discontinuation
- 1985-11-29 HU HU854577A patent/HU194154B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE35130T1 (de) | 1988-07-15 |
| US4720572A (en) | 1988-01-19 |
| EP0183149A3 (de) | 1987-03-04 |
| EP0183149A2 (de) | 1986-06-04 |
| EP0183149B1 (en) | 1988-06-15 |
| ES549357A0 (es) | 1987-02-16 |
| KR860004004A (ko) | 1986-06-16 |
| JPS61134351A (ja) | 1986-06-21 |
| DE3443678A1 (de) | 1986-06-05 |
| HUT40995A (en) | 1987-03-30 |
| HU194154B (en) | 1988-01-28 |
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