ES482178A1 - Un procedimiento para la preparacion de 2-ciano-3-azabiciclo-3.1.0-hexano. - Google Patents
Un procedimiento para la preparacion de 2-ciano-3-azabiciclo-3.1.0-hexano.Info
- Publication number
- ES482178A1 ES482178A1 ES482178A ES482178A ES482178A1 ES 482178 A1 ES482178 A1 ES 482178A1 ES 482178 A ES482178 A ES 482178A ES 482178 A ES482178 A ES 482178A ES 482178 A1 ES482178 A1 ES 482178A1
- Authority
- ES
- Spain
- Prior art keywords
- azabicyclo
- hexane
- treating
- solution
- azabiciclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PRSVJIWYTOZNIT-UHFFFAOYSA-N 3-azabicyclo[3.1.0]hex-2-ene Chemical compound C1N=CC2CC21 PRSVJIWYTOZNIT-UHFFFAOYSA-N 0.000 abstract 2
- JFUYLMCSIHJLOX-UHFFFAOYSA-N 3-azabicyclo[3.1.0]hexane-2-carbonitrile Chemical compound N#CC1NCC2CC12 JFUYLMCSIHJLOX-UHFFFAOYSA-N 0.000 abstract 2
- JBDOTWVUXVXVDR-UHFFFAOYSA-N 3-azoniabicyclo[3.1.0]hexane-2-carboxylate Chemical compound OC(=O)C1NCC2CC12 JBDOTWVUXVXVDR-UHFFFAOYSA-N 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- -1 alkali metal bisulfite Chemical class 0.000 abstract 2
- RYPKRALMXUUNKS-UHFFFAOYSA-N hex-2-ene Chemical compound CCCC=CC RYPKRALMXUUNKS-UHFFFAOYSA-N 0.000 abstract 2
- HGWUUOXXAIISDB-UHFFFAOYSA-N 3-azabicyclo[3.1.0]hexane Chemical compound C1NCC2CC21 HGWUUOXXAIISDB-UHFFFAOYSA-N 0.000 abstract 1
- QYCLXTCXSIUGSB-UHFFFAOYSA-N 3-chloro-3-azabicyclo[3.1.0]hexane Chemical compound C1N(Cl)CC2CC21 QYCLXTCXSIUGSB-UHFFFAOYSA-N 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- WESJNFANGQJVKA-UHFFFAOYSA-M sodium;2,3-dichloro-2-methylpropanoate Chemical compound [Na+].ClCC(Cl)(C)C([O-])=O WESJNFANGQJVKA-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/922,408 US4225499A (en) | 1978-07-06 | 1978-07-06 | Process for preparing 3-azabicyclo(3.1.0)hexane-2-carbonitrile |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES482178A1 true ES482178A1 (es) | 1980-04-01 |
Family
ID=25446988
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES482178A Expired ES482178A1 (es) | 1978-07-06 | 1979-07-04 | Un procedimiento para la preparacion de 2-ciano-3-azabiciclo-3.1.0-hexano. |
| ES484543A Expired ES484543A1 (es) | 1978-07-06 | 1979-09-28 | Un procedimiento para la preparacion de 2-carboxi-3-azabici-clo (3.1.0)hexano |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES484543A Expired ES484543A1 (es) | 1978-07-06 | 1979-09-28 | Un procedimiento para la preparacion de 2-carboxi-3-azabici-clo (3.1.0)hexano |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4225499A (OSRAM) |
| EP (1) | EP0008813B1 (OSRAM) |
| JP (1) | JPS5511588A (OSRAM) |
| AU (1) | AU528623B2 (OSRAM) |
| BR (1) | BR7904219A (OSRAM) |
| CA (1) | CA1116613A (OSRAM) |
| CS (1) | CS210691B2 (OSRAM) |
| DD (1) | DD144769A5 (OSRAM) |
| DE (1) | DE2964138D1 (OSRAM) |
| DK (1) | DK241079A (OSRAM) |
| ES (2) | ES482178A1 (OSRAM) |
| IL (1) | IL57719A0 (OSRAM) |
| PL (1) | PL118592B1 (OSRAM) |
| ZA (1) | ZA793335B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1117128A (en) * | 1978-10-27 | 1982-01-26 | Derek A. Wood | 2-cyano-3-azabicyclo(3.1.0)hexane |
| JP5431956B2 (ja) * | 2006-12-20 | 2014-03-05 | メルク・シャープ・アンド・ドーム・コーポレーション | 重亜硫酸塩中間体を使用した６，６−ジメチル−３−アザビシクロ［３．１．０］ヘキサン化合物の調製方法 |
| EP2481737A1 (en) * | 2008-06-24 | 2012-08-01 | Merck Sharp & Dohme Corp. | Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds |
| CN116987022A (zh) * | 2022-04-25 | 2023-11-03 | 台州臻挚生物科技有限公司 | 一种含有氮杂双环-[3.1.0]-己烷-2-酮的化合物的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2479942A (en) * | 1946-01-05 | 1949-08-23 | American Cyanamid Co | Alkenylaminoacetonitriles |
| JPS5247918A (en) * | 1975-10-15 | 1977-04-16 | Sumitomo Chem Co Ltd | Non-medical fungicides and method of making the same |
| FI763359A7 (OSRAM) * | 1975-12-02 | 1977-06-03 | Sandoz Ag | |
| GR72713B (OSRAM) * | 1976-09-15 | 1983-12-01 | American Cyanamid Co |
-
1978
- 1978-07-06 US US05/922,408 patent/US4225499A/en not_active Expired - Lifetime
-
1979
- 1979-06-08 DK DK241079A patent/DK241079A/da not_active Application Discontinuation
- 1979-06-14 CA CA000329752A patent/CA1116613A/en not_active Expired
- 1979-06-27 DE DE7979200348T patent/DE2964138D1/de not_active Expired
- 1979-06-27 EP EP79200348A patent/EP0008813B1/en not_active Expired
- 1979-07-04 PL PL1979216849A patent/PL118592B1/pl unknown
- 1979-07-04 ES ES482178A patent/ES482178A1/es not_active Expired
- 1979-07-04 JP JP8405179A patent/JPS5511588A/ja active Granted
- 1979-07-04 IL IL57719A patent/IL57719A0/xx unknown
- 1979-07-04 CS CS794718A patent/CS210691B2/cs unknown
- 1979-07-04 ZA ZA793335A patent/ZA793335B/xx unknown
- 1979-07-04 BR BR7904219A patent/BR7904219A/pt unknown
- 1979-07-04 AU AU48637/79A patent/AU528623B2/en not_active Ceased
- 1979-07-04 DD DD79214105A patent/DD144769A5/de unknown
- 1979-09-28 ES ES484543A patent/ES484543A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU528623B2 (en) | 1983-05-05 |
| DK241079A (da) | 1980-01-07 |
| JPS5511588A (en) | 1980-01-26 |
| AU4863779A (en) | 1980-01-10 |
| DD144769A5 (de) | 1980-11-05 |
| EP0008813A1 (en) | 1980-03-19 |
| DE2964138D1 (en) | 1983-01-05 |
| US4225499A (en) | 1980-09-30 |
| CA1116613A (en) | 1982-01-19 |
| EP0008813B1 (en) | 1982-12-01 |
| CS210691B2 (en) | 1982-01-29 |
| PL118592B1 (en) | 1981-10-31 |
| ES484543A1 (es) | 1980-05-16 |
| BR7904219A (pt) | 1980-03-18 |
| PL216849A1 (OSRAM) | 1980-03-24 |
| JPS6230186B2 (OSRAM) | 1987-07-01 |
| ZA793335B (en) | 1980-06-25 |
| IL57719A0 (en) | 1979-11-30 |
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