ES479388A1 - Procedimiento para la obtencion de derivados de cromanona. - Google Patents

Procedimiento para la obtencion de derivados de cromanona.

Info

Publication number
ES479388A1
ES479388A1 ES479388A ES479388A ES479388A1 ES 479388 A1 ES479388 A1 ES 479388A1 ES 479388 A ES479388 A ES 479388A ES 479388 A ES479388 A ES 479388A ES 479388 A1 ES479388 A1 ES 479388A1
Authority
ES
Spain
Prior art keywords
nitro
aryl
alkyl
cyano
denotes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES479388A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES479388A1 publication Critical patent/ES479388A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedimiento para la obtención de derivados de cromanona de fórmula **fórmula** donde los sustituyentes R1 y R2 son iguales o diferentes y significan hidrógeno , alquilo, en cada dado sustituido, alquenilo, ciloalquilo, en caso dado sustituido, cicloalquenilo, en caso dado sustituido, arilo, en caso dado sustituido, aralquilo, en caso dado sustituido, alcoxicarbonilo, cazrboxilo, dialquilaminoalquilo, un heterociclo, en caso dado sustituido o donde los sustituyentes R1 y R2 junto con el átomo de carbono encerrado por ellos forman un anillo carbocíclico, en caso dado sustituido o un anillo heterociclico, en caso dado sustituido.
ES479388A 1978-04-07 1979-04-06 Procedimiento para la obtencion de derivados de cromanona. Expired ES479388A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782814983 DE2814983A1 (de) 1978-04-07 1978-04-07 Neue chromanon-derivate

Publications (1)

Publication Number Publication Date
ES479388A1 true ES479388A1 (es) 1982-12-01

Family

ID=6036342

Family Applications (1)

Application Number Title Priority Date Filing Date
ES479388A Expired ES479388A1 (es) 1978-04-07 1979-04-06 Procedimiento para la obtencion de derivados de cromanona.

Country Status (7)

Country Link
US (1) US4261988A (es)
EP (1) EP0004624B1 (es)
JP (1) JPS54132576A (es)
AT (1) AT361922B (es)
DE (2) DE2814983A1 (es)
DK (1) DK143979A (es)
ES (1) ES479388A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
WO2002020509A2 (de) * 2000-09-06 2002-03-14 Bayer Aktiengesellschaft Arzneimittel gegen virale erkrankungen
DE10328049A1 (de) * 2003-06-20 2005-01-13 Ernst-Moritz-Arndt-Universität Neue antimikrobielle Chroman-4-one
WO2007011809A1 (en) 2005-07-19 2007-01-25 Merck & Co., Inc. Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors
JP5271917B2 (ja) * 2007-01-12 2013-08-21 メルク・シャープ・アンド・ドーム・コーポレーション スピロクロマノン誘導体
PE20081559A1 (es) * 2007-01-12 2008-11-20 Merck & Co Inc DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3410851A (en) * 1963-09-03 1968-11-12 Miles Lab Derivatives of flavone
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
US3825539A (en) * 1967-09-26 1974-07-23 Colgate Palmolive Co 4h(1)benzopyrano(3,4-d)isoxazole derivatives
US3704323A (en) * 1969-12-23 1972-11-28 Squibb & Sons Inc Indane derivatives
US3753985A (en) * 1970-12-28 1973-08-21 Miles Lab 3-amino-flavanones
DE2535338A1 (de) * 1975-08-07 1977-02-17 Bayer Ag Chromanone-(4)

Also Published As

Publication number Publication date
DE2962169D1 (en) 1982-03-25
EP0004624A3 (en) 1979-10-31
DK143979A (da) 1979-10-08
JPS54132576A (en) 1979-10-15
US4261988A (en) 1981-04-14
EP0004624A2 (de) 1979-10-17
DE2814983A1 (de) 1979-10-18
AT361922B (de) 1981-04-10
ATA257079A (de) 1980-09-15
EP0004624B1 (de) 1982-02-24

Similar Documents

Publication Publication Date Title
ES473451A1 (es) Un procedimiento para la preparacion de derivados de imida- zol.
MY102866A (en) Amide derivatives.
GB1069343A (en) Propanolamine derivatives
ES8700660A1 (es) Un procedimiento para la preparacion de derivados de bencimidasol.
FI80877B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara spiro/4,(3+n)/-2-azaalkan-3-karboxylsyraderivat och vid framstaellning av dessa anvaendbara foerening.
ES8700851A1 (es) Procedimiento para la obtencion de acido alquil-1- ciclopropil-1, 4-dihidro-4-oxo-3-quinolincarboxilico.
ES8107201A1 (es) Un procedimiento para la preparacion de derivados de morfo- lina
ATE283268T1 (de) 2-adamantylethylamine und deren verwendung bei der behandlung von abnormalitäten in der glutamat transmission
GB1459571A (en) Thiophene-2-sulphonamide derivatives and their use as therapeutic agents sheet orienting apparatus
ES8504737A1 (es) Procedimiento para la obtencion de nuevos derivados de mercaptoimidazol
ES479388A1 (es) Procedimiento para la obtencion de derivados de cromanona.
GB1086192A (en) Phenylcyclopropane derivatives
DE3363248D1 (en) Use of pyridine compounds for the manufacture of medicaments with an antihypoxemia and ischemia-protective activity
ES433148A1 (es) Procedimiento para preparar derivados de pirazol.
NO160783C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive substituerte beta-karbolinderivater.
ES8400440A1 (es) "procedimiento para preparar nuevas triazoloquinazolonas".
NO162907C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive bis-(piperazinyl-resp. homopiperazinyl)-alkaner.
ES399808A1 (es) Procedimiento para la preparacion de nuevos n-acil-biscar- bamatos herbicidas.
ES488901A1 (es) Procedimiento de preparacion de nuevos derivados de benzoil-2 glicilanilidas substituidas
ES8801205A1 (es) Un procedimiento para la produccion de una isatina y una sal de la misma
ES8107212A1 (es) Procedimiento para la preparacion de derivados de 3-amino-1-benzoxepin-5(2h)-ona
ES444290A1 (es) Un procedimiento para la produccion de derivados de ferroce-no.
ES479110A1 (es) Procedimiento para preparar derivados de benzamidina.
ES475120A1 (es) Un procedimiento para la preparacion de imidazo (1,5-b)piri-dazinas.
ES8104269A1 (es) Procedimiento para la preparacion de nuevos derivados de 3-amino-1-benzoxepina