ES478886A1 - Procedimiento de isomerizacion de derivados de la 3-vinil piperidina. - Google Patents

Procedimiento de isomerizacion de derivados de la 3-vinil piperidina.

Info

Publication number
ES478886A1
ES478886A1 ES478886A ES478886A ES478886A1 ES 478886 A1 ES478886 A1 ES 478886A1 ES 478886 A ES478886 A ES 478886A ES 478886 A ES478886 A ES 478886A ES 478886 A1 ES478886 A1 ES 478886A1
Authority
ES
Spain
Prior art keywords
formula
vinyl group
configuration
carbon carrying
rectus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES478886A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmindustrie
Original Assignee
Pharmindustrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7808449A external-priority patent/FR2420528A1/fr
Priority claimed from FR7903291A external-priority patent/FR2448530A1/fr
Application filed by Pharmindustrie filed Critical Pharmindustrie
Publication of ES478886A1 publication Critical patent/ES478886A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Abstract

Procedimiento de transformación de los compuestos de fórmula: *** ver imagen 01 en la cual R es un átomo de hidrógeno o un sustituyente y para los cuales el carbono portador del grupo vinilo tiene la configuración rectus en los compuestos correspondientes de fórmula (I) para los cuales el carbono portador del grupo vinilo tiene la configuración sinister, y viceversa, caracterizado porque se calienta a temperatura superior a los 50ºC, dentro de un disolvente prótico o de una mezcla de disolventes próticos, en presencia o en ausencia de formaldehído, un compuesto de fórmula (I) para el cual el carbono portador del grupo vinilo tiene la configuración rectus o sinister, parcialmente o totalmente salificada.
ES478886A 1978-03-23 1979-03-22 Procedimiento de isomerizacion de derivados de la 3-vinil piperidina. Expired ES478886A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7808449A FR2420528A1 (fr) 1978-03-23 1978-03-23 Procede d'isomerisation des derives de la vinyl-3 piperidine
FR7903291A FR2448530A1 (fr) 1979-02-09 1979-02-09 Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeres

Publications (1)

Publication Number Publication Date
ES478886A1 true ES478886A1 (es) 1979-07-01

Family

ID=26220516

Family Applications (1)

Application Number Title Priority Date Filing Date
ES478886A Expired ES478886A1 (es) 1978-03-23 1979-03-22 Procedimiento de isomerizacion de derivados de la 3-vinil piperidina.

Country Status (15)

Country Link
US (1) US4238612A (es)
EP (1) EP0005654B1 (es)
JP (1) JPS54135775A (es)
AR (1) AR227873A1 (es)
AT (1) AT370412B (es)
AU (1) AU524171B2 (es)
CA (1) CA1127647A (es)
DE (1) DE2961396D1 (es)
DK (1) DK150616C (es)
ES (1) ES478886A1 (es)
GR (1) GR69926B (es)
HU (1) HU181929B (es)
IL (1) IL56815A (es)
NO (1) NO153651C (es)
PT (1) PT69327A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908031A (nl) * 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
GR74482B (es) * 1980-03-06 1984-06-28 Acf Chemiefarma Nv
US4442107A (en) * 1980-03-06 1984-04-10 Acf Chemiefarma N.V. Quinoline derivatives, pharmaceutical compositions containing such compounds, and methods for treating cardiovascular conditions with them
IL62240A0 (en) * 1980-03-06 1981-05-20 Acf Chemiefarma Nv Novel quinoline derivatives,pharmaceutical compositions containing such compounds,and methods for the preparation of these compounds
FR2485014A1 (fr) * 1980-06-20 1981-12-24 Pharmindustrie Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857846A (en) * 1968-07-02 1974-12-31 Hoffmann La Roche {60 -{8 1-benzoyl-3r-alkyl-4(r)-piperidylmethyl{9 {62 -oxo-{62 (6,7 substituted-4 quinolyl)propionic acid and racemates
US3753992A (en) * 1968-07-02 1973-08-21 Hoffmann La Roche Process and intermediates for quinine,quinidine and derivatives thereof
JPS497160A (es) * 1972-05-15 1974-01-22
FR2354771A1 (fr) * 1976-06-18 1978-01-13 Mar Pha Etu Expl Marques ((quinolyl-4)-3 propyl-1) -4 piperidines, leur preparation et leur utilisation comme medicaments

Also Published As

Publication number Publication date
EP0005654B1 (fr) 1981-11-25
JPS54135775A (en) 1979-10-22
DE2961396D1 (en) 1982-01-28
AU524171B2 (en) 1982-09-02
IL56815A0 (en) 1979-05-31
US4238612A (en) 1980-12-09
PT69327A (fr) 1979-04-01
GR69926B (es) 1982-07-21
NO153651C (no) 1986-04-30
AU4533379A (en) 1979-09-27
IL56815A (en) 1982-04-30
DK111779A (da) 1979-09-24
DK150616C (da) 1987-11-23
ATA212179A (de) 1982-08-15
CA1127647A (fr) 1982-07-13
AT370412B (de) 1983-03-25
AR227873A1 (es) 1982-12-30
NO153651B (no) 1986-01-20
HU181929B (en) 1983-11-28
DK150616B (da) 1987-04-21
EP0005654A1 (fr) 1979-11-28
JPS6140225B2 (es) 1986-09-08
NO790972L (no) 1979-09-25

Similar Documents

Publication Publication Date Title
JPS51138704A (en) Method and apparatus for producing synthetic fuel from solid waste
ES478886A1 (es) Procedimiento de isomerizacion de derivados de la 3-vinil piperidina.
GB864198A (en) A process for the manufacture of ferrocene derivatives
ES8609195A1 (es) Un nuevo procedimiento para la preparacion de derivados del acido cicloalquilidenmetilfenilacetico.
GB2036003A (en) Alkylation method of 4(5)-mercaptomethyl-imidazol with aziridin derivatives
ES483249A1 (es) Procedimiento para la obtencion de diciclopentilen(2,2'-bis (4-alquil-6-t-butilfenoles).
ES481264A1 (es) Procedimiento para fabricar derivados del acido arilacetico.
JPS51118741A (en) Process for preparation of ortho-chlorobenzonitrile
CH614932A5 (en) Process for the preparation of new terpenoaromatic amidines
ES416476A1 (es) Procedimiento para la transformacion de compuestos s-oxido de penicilina en compuestos de desacetoxicefalosporina.
ES471267A1 (es) Procedimiento para la preparacion de alquilo inferior 2-tri-(inferior) alquilsililacetileno-n-carbetoxiglicinatos y ami-no acidos derivados de ellos
JPS5446708A (en) Preparation of 2, 2, 4-trimethyl-1, 3-pentane-diol diisobutylate
AU529864B2 (en) Isomerization of 3-azabicyclo (3.1.0) hexane derivatives
JPS51138664A (en) Process for preparing 4-exo-hydroxy-endo-tri cyclo 95.2.2.02,6)-undeca-8-ene
JPS57102876A (en) Preparation of benzoxazolone and benzthiazolone
JPS56124387A (en) Production of terpene acid
JPS51125062A (en) A process for preparing 3-aminoazetidinone
JPS51146481A (en) Process for preparing arabinofuranosylcytosine derivatives
JPS51138642A (en) Process for preparing guanidinobenzoic acid derivatives
JPS51124122A (en) Process for producing azo dyes
JPS5350231A (en) Preparation of quinoline
ES435698A1 (es) Un metodo para la preparacion de acido 3-(benzoil trisusti-tuido)-propionico.
JPS51125063A (en) A process for preparing 3-aminoazetidinone derivatives
ES447349A1 (es) Un procedimiento para la preparacion de nuevos derivados delacido 8-azaprostanoico.
ES453718A1 (es) Un procedimiento analogico de preparacion de una sal de adi-cion de acido.