FR2448530A1 - Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeres - Google Patents
Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeresInfo
- Publication number
- FR2448530A1 FR2448530A1 FR7903291A FR7903291A FR2448530A1 FR 2448530 A1 FR2448530 A1 FR 2448530A1 FR 7903291 A FR7903291 A FR 7903291A FR 7903291 A FR7903291 A FR 7903291A FR 2448530 A1 FR2448530 A1 FR 2448530A1
- Authority
- FR
- France
- Prior art keywords
- epimerisation
- heating
- protonic solvent
- cpds
- piperidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDE DE TRANSFORMATION DES COMPOSES DE FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST UN ATOME D'HYDROGENE OU UN SUBSTITUANT ET POUR LESQUELS LE CARBONE PORTEUR DU GROUPE VINYLE POSSEDE LA CONFIGURATION RECTUS EN LES COMPOSES CORRESPONDANTS DE FORMULE I POUR LESQUELS LE CARBONE PORTEUR DU GROUPE VINYLE POSSEDE LA CONFIGURATION SINISTER, ET VICE VERSA, CARACTERISE EN CE QUE L'ON CHAUFFE A TEMPERATURE SUPERIEURE A 50C, AU SEIN D'UN SOLVANT PROTIQUE OU D'UN MELANGE DE SOLVANTS PROTIQUES, EN PRESENCE OU EN L'ABSENCE DE FORMALDEHYDE, UN COMPOSE DE FORMULE I POUR LEQUEL LE CARBONE PORTEUR DU GROUPE VINYLE A LA CONFIGURATION RECTUS OU SINISTER, PARTIELLEMENT OU TOTALEMENT SALIFIE, ET ISOLE LE COMPOSE DE FORMULE I POUR LEQUEL LE CARBONE PORTEUR DU GROUPE VINYLE A LA CONFIGURATION SINISTER OU RECTUS AINSI FORME. LES COMPOSES OBTENUS SONT UTILISABLES EN PARTICULIER COMME PRODUITS INTERMEDIAIRES POUR LA PREPARATION DE MEDICAMENTS.
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7903291A FR2448530A1 (fr) | 1979-02-09 | 1979-02-09 | Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeres |
GR58494A GR69926B (fr) | 1978-03-23 | 1979-02-27 | |
IL56815A IL56815A (en) | 1978-03-23 | 1979-03-07 | Epimerisation of 3-vinylpiperidine derivatives |
PT69327A PT69327A (fr) | 1978-03-23 | 1979-03-09 | Procede d'isomerisation des derives de la vinyl-3 piperidine |
DE7979400167T DE2961396D1 (en) | 1978-03-23 | 1979-03-14 | Process for the isomerization of 3-vinyl-piperidine derivatives |
EP79400167A EP0005654B1 (fr) | 1978-03-23 | 1979-03-14 | Procédé d'isomérisation des dérivés de la vinyl-3 pipéridine |
DK111779A DK150616C (da) | 1978-03-23 | 1979-03-19 | Fremgangsmaade til isomerisering af derivater af 3-vinylpiperidin |
JP3317079A JPS54135775A (en) | 1978-03-23 | 1979-03-20 | Isomerization of 33vinylpiperidine derivative |
AT0212179A AT370412B (de) | 1978-03-23 | 1979-03-21 | Verfahren zur umwandlung von 3-vinylpiperidinderivaten in ihre epimere |
US06/022,544 US4238612A (en) | 1978-03-23 | 1979-03-21 | Process for the isomerization of derivatives of 3-vinyl-piperidine |
NO790972A NO153651C (no) | 1978-03-23 | 1979-03-22 | Fremgangsmaate for isomerisering av derivater av 3-vinylpiperidin. |
AR275909A AR227873A1 (es) | 1978-03-23 | 1979-03-22 | Un procedimiento de isomerizacion de derivados de vinil-3-piperidina |
AU45333/79A AU524171B2 (en) | 1978-03-23 | 1979-03-22 | Isomerisation of derivatives of 3-vinyl-piperidine |
CA324,087A CA1127647A (fr) | 1978-03-23 | 1979-03-22 | Procede d'isomerisation des derives de la vinyl-3 piperidine |
ES478886A ES478886A1 (es) | 1978-03-23 | 1979-03-22 | Procedimiento de isomerizacion de derivados de la 3-vinil piperidina. |
MX10118679U MX5638E (es) | 1978-03-23 | 1979-03-22 | Procedimiento de isomerizacion de los derivados de la vinil-3 piperidina |
HU79PA1348A HU181929B (en) | 1978-03-23 | 1979-03-22 | Process for producing 3-vinyl-piperidine derivatives with isomerisation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7903291A FR2448530A1 (fr) | 1979-02-09 | 1979-02-09 | Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeres |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2448530A1 true FR2448530A1 (fr) | 1980-09-05 |
FR2448530B1 FR2448530B1 (fr) | 1984-05-04 |
Family
ID=9221765
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7903291A Granted FR2448530A1 (fr) | 1978-03-23 | 1979-02-09 | Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeres |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2448530A1 (fr) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2354771A1 (fr) * | 1976-06-18 | 1978-01-13 | Mar Pha Etu Expl Marques | ((quinolyl-4)-3 propyl-1) -4 piperidines, leur preparation et leur utilisation comme medicaments |
-
1979
- 1979-02-09 FR FR7903291A patent/FR2448530A1/fr active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2354771A1 (fr) * | 1976-06-18 | 1978-01-13 | Mar Pha Etu Expl Marques | ((quinolyl-4)-3 propyl-1) -4 piperidines, leur preparation et leur utilisation comme medicaments |
Non-Patent Citations (1)
Title |
---|
EXBK/72 * |
Also Published As
Publication number | Publication date |
---|---|
FR2448530B1 (fr) | 1984-05-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE791565L (en) | Crop cutting apparatus | |
ATE150462T1 (de) | Pyrazolopyridinverbindungen und verfahren zu ihrer herstellung | |
FI906438A (fi) | Menetelmä uusien, terapeuttisesti käyttökelpoisten A-nor-steroidi-3-karboksyylihappojohdannaisten valmistamiseksi | |
AU4541689A (en) | Quinazolinonederivatives which are bronchodilators and vasodilators | |
ES468378A1 (es) | Procedimiento de preparacion de un derivado de acetamina. | |
NO883587L (no) | Fremgangsmaate for fremstilling av terapeutisk aktive indolderivater. | |
NO891350D0 (no) | Acylderivater. | |
PT83104B (en) | Novel guanidinomethylbenzoic acid derivatives | |
DE69123000D1 (de) | Neue tricyclische Verbindung oder Salze davon, Verfahren zur Herstellung und antimikrobieller Wirkstoff, der sie enthält | |
JPS5665869A (en) | Novel 22hydroxyalkyll3*4*55trihydroxyypiperidine compound* its manufacture and drug | |
ATE1609T1 (de) | Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
EP0546177A4 (fr) | Derive de benzopyrane, sa production, et composition pharmaceutique le contenant. | |
EP0103320A3 (en) | Acetylsalicylic acid thioesters, a process for their preparation and pharmaceutical compositions containing them | |
DE2964736D1 (en) | 1-acyloxyphenyl-1,2-diphenylalkene derivatives, processes for their manufacture and a pharmaceutical composition containing these derivatives | |
FR2448530A1 (fr) | Procede de transformation de derives de la vinyl -3 piperidine en leurs epimeres | |
FR2321294A1 (fr) | Derives d'acides 7b-amino-3-cephem-3-carbonylmethyl-4-carboxyliques utiles comme medicaments | |
ATE3769T1 (de) | 1-imidazol-2-yliden-3-thienyl-harnstoffderivate verfahren zu deren herstellung und pharmazeutische zusammensetzungen. | |
ES8201169A1 (es) | Un procedimiento para la preparacion de derivados de quina- zolina | |
IT7825713A0 (it) | Derivati d'acido ciclopropancarbossilico, processo per la loro produzione e loro impiego come prodotti per laproduzione d'insetticidi. | |
ATE9584T1 (de) | Antibakterielle beta-lactam-verbindungen, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen. | |
ES8101646A1 (es) | Un procedimiento para producir un compuesto opticamente ac- tivo | |
BE848118A (fr) | Procede de production d'un compose extincteur, | |
PT73948A (en) | Process for the preparation of biologically active heterobicyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof | |
RU93051079A (ru) | Фармацевтические соединения, способ получения, фармацевтическая композиция | |
ES8200142A1 (es) | Un procedimiento para la produccion de analogos de cefalosporina. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |