ES477653A1 - Un procedimiento para la preparacion de nuevos derivados de aminoazucares. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de aminoazucares.

Info

Publication number
ES477653A1
ES477653A1 ES477653A ES477653A ES477653A1 ES 477653 A1 ES477653 A1 ES 477653A1 ES 477653 A ES477653 A ES 477653A ES 477653 A ES477653 A ES 477653A ES 477653 A1 ES477653 A1 ES 477653A1
Authority
ES
Spain
Prior art keywords
preparation
trestatin
sugar derivatives
amino sugar
new amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477653A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES477653A1 publication Critical patent/ES477653A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99Enzyme inactivation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES477653A 1978-02-14 1979-02-13 Un procedimiento para la preparacion de nuevos derivados de aminoazucares. Expired ES477653A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB583478 1978-02-14

Publications (1)

Publication Number Publication Date
ES477653A1 true ES477653A1 (es) 1980-03-01

Family

ID=9803510

Family Applications (1)

Application Number Title Priority Date Filing Date
ES477653A Expired ES477653A1 (es) 1978-02-14 1979-02-13 Un procedimiento para la preparacion de nuevos derivados de aminoazucares.

Country Status (26)

Country Link
US (1) US4273765A (index.php)
EP (1) EP0003616B1 (index.php)
JP (1) JPS54163511A (index.php)
AR (1) AR219150A1 (index.php)
AT (1) AT367451B (index.php)
AU (1) AU527318B2 (index.php)
CA (1) CA1121290A (index.php)
DE (2) DE2962165D1 (index.php)
DK (1) DK149599C (index.php)
ES (1) ES477653A1 (index.php)
FI (1) FI63062C (index.php)
FR (1) FR2416901A1 (index.php)
GR (1) GR72817B (index.php)
HU (1) HU181442B (index.php)
IE (1) IE47916B1 (index.php)
IL (1) IL56626A0 (index.php)
LU (1) LU80906A1 (index.php)
MC (1) MC1253A1 (index.php)
NL (1) NL7901182A (index.php)
NO (1) NO153011C (index.php)
NZ (1) NZ189625A (index.php)
PH (1) PH15084A (index.php)
PT (1) PT69218A (index.php)
SE (1) SE7901276L (index.php)
YU (1) YU41437B (index.php)
ZA (1) ZA79528B (index.php)

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EP0056194B1 (en) 1981-01-05 1984-09-12 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4885361A (en) * 1987-07-31 1989-12-05 Hoffmann-La Roche Inc. Sulfated oligosaccharides
DE69115926T2 (de) * 1990-11-30 1996-05-30 Monoclonetics Int Verfahren zur diagnose chronischer niedriger rückenschmerzen und nackenschmerzen
CA2128044C (en) * 1993-08-05 2007-02-20 Klaus-Dieter Bremer Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
DK1157696T3 (da) * 2000-05-24 2007-02-12 Pfizer Behandling af rumen-acidose med alpha-amylaseinhibitorer
US7022684B2 (en) * 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
RU2422450C2 (ru) 2003-11-19 2011-06-27 Метабазис Терапеутикс, Инк. Новые фосфорсодержащие тиромиметики
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
BRPI0518300A2 (pt) * 2004-11-23 2008-11-11 Warner Lambert Co derivados de Ácido 7-(2h-pirazol-3-il)-3,5-diidràxi-heptanàico como inibidores da hmg co-a reductase para o tratamento de lipidemia
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
DK2170930T3 (da) 2007-06-04 2012-11-05 Synergy Pharmaceuticals Inc Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
CN101998998A (zh) 2008-04-11 2011-03-30 安斯泰来制药株式会社 氨基糖化合物及其生产方法
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
EP2571860A1 (en) 2010-05-21 2013-03-27 Pfizer Inc 2-phenyl benzoylamides
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2828343A1 (en) 2011-03-04 2012-09-13 The Scripps Research Institute Edn3-like peptides and uses thereof
MY188344A (en) 2012-03-09 2021-12-01 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
RU2746405C2 (ru) 2014-08-29 2021-04-13 Тес Фарма С.Р.Л. ИНГИБИТОРЫ α-АМИНО-β-КАРБОКСИМУКОНАТ-ε-СЕМИАЛЬДЕГИД-ДЕКАРБОКСИЛАЗЫ
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JP2020500838A (ja) 2016-10-14 2020-01-16 ティエエッセ ファルマ ソチエタ レスポンサビリタ リミタータ Α−アミノ−β−カルボキシムコン酸セミアルデヒドデカルボキシラーゼの阻害剤
IL283182B2 (en) 2018-11-20 2025-10-01 Tes Pharma S R L Alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase inhibitors
PL3911648T3 (pl) 2019-01-18 2025-03-10 Astrazeneca Ab 6'-[[(1s,3s)-3-[[5-(difluorometoksy)-2- pirymidynylo]amino]cyklopentylo]amino][1(2h),3'-bipirydyn]-2-on jako inhibitor pcsk9 i sposoby jego zastosowania

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en) 1975-03-19 1979-02-06 American Cyanamid Company Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
AR219150A1 (es) 1980-07-31
EP0003616B1 (de) 1982-02-24
US4273765A (en) 1981-06-16
IL56626A0 (en) 1979-05-31
SE7901276L (sv) 1979-08-15
GR72817B (index.php) 1983-12-06
DK61179A (da) 1979-08-15
CA1121290A (en) 1982-04-06
FI790486A7 (fi) 1979-08-15
IE790274L (en) 1979-08-14
PH15084A (en) 1982-07-02
NL7901182A (nl) 1979-08-16
DE2905649A1 (de) 1979-08-16
ATA108879A (de) 1981-11-15
PT69218A (en) 1979-03-01
AU4402879A (en) 1979-08-23
YU34879A (en) 1983-01-21
NO153011C (no) 1986-01-02
FI63062B (fi) 1982-12-31
MC1253A1 (fr) 1980-01-14
YU41437B (en) 1987-06-30
HU181442B (en) 1983-07-28
EP0003616A2 (de) 1979-08-22
LU80906A1 (de) 1980-09-24
DK149599C (da) 1987-06-01
JPS643877B2 (index.php) 1989-01-23
IE47916B1 (en) 1984-07-25
AT367451B (de) 1982-07-12
NZ189625A (en) 1981-05-01
NO790469L (no) 1979-08-15
NO153011B (no) 1985-09-23
FR2416901A1 (fr) 1979-09-07
EP0003616A3 (en) 1979-09-05
JPS54163511A (en) 1979-12-26
FI63062C (fi) 1983-04-11
AU527318B2 (en) 1983-02-24
FR2416901B1 (index.php) 1980-10-24
DE2962165D1 (en) 1982-03-25
ZA79528B (en) 1980-02-27
DK149599B (da) 1986-08-04

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519