ES476917A1 - Un procedimiento para la preparacion de derivados de acido -4-piridon-3-carboxilico. - Google Patents
Un procedimiento para la preparacion de derivados de acido -4-piridon-3-carboxilico.Info
- Publication number
- ES476917A1 ES476917A1 ES476917A ES476917A ES476917A1 ES 476917 A1 ES476917 A1 ES 476917A1 ES 476917 A ES476917 A ES 476917A ES 476917 A ES476917 A ES 476917A ES 476917 A1 ES476917 A1 ES 476917A1
- Authority
- ES
- Spain
- Prior art keywords
- carboxylic acid
- acid derivatives
- preparation
- pyridone
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- NXFQHRVNIOXGAQ-YCRREMRBSA-N nitrofurantoin Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)NC(=O)C1 NXFQHRVNIOXGAQ-YCRREMRBSA-N 0.000 abstract 1
- 229960000564 nitrofurantoin Drugs 0.000 abstract 1
- XXPANQJNYNUNES-UHFFFAOYSA-N nomifensine Chemical compound C12=CC=CC(N)=C2CN(C)CC1C1=CC=CC=C1 XXPANQJNYNUNES-UHFFFAOYSA-N 0.000 abstract 1
- 229960001073 nomifensine Drugs 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH51278A CH639073A5 (en) | 1978-01-18 | 1978-01-18 | 4-Pyridone-3-carboxylic acid derivatives and their preparation |
| CH1173478 | 1978-11-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES476917A1 true ES476917A1 (es) | 1979-11-16 |
Family
ID=25684790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES476917A Expired ES476917A1 (es) | 1978-01-18 | 1979-01-17 | Un procedimiento para la preparacion de derivados de acido -4-piridon-3-carboxilico. |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US4521535A (enExample) |
| EP (1) | EP0003144B1 (enExample) |
| JP (1) | JPS54100382A (enExample) |
| KR (1) | KR820002111B1 (enExample) |
| AR (1) | AR223663A1 (enExample) |
| AT (1) | AT369731B (enExample) |
| AU (1) | AU521148B2 (enExample) |
| CA (1) | CA1110234A (enExample) |
| DE (1) | DE2901868A1 (enExample) |
| DK (1) | DK20279A (enExample) |
| ES (1) | ES476917A1 (enExample) |
| FI (1) | FI790103A7 (enExample) |
| FR (1) | FR2415103A1 (enExample) |
| GB (1) | GB2013190B (enExample) |
| GR (1) | GR73088B (enExample) |
| HU (1) | HU179487B (enExample) |
| IE (1) | IE47784B1 (enExample) |
| IL (1) | IL56421A (enExample) |
| LU (1) | LU80794A1 (enExample) |
| MC (1) | MC1239A1 (enExample) |
| NL (1) | NL7900264A (enExample) |
| NO (1) | NO152089C (enExample) |
| NZ (1) | NZ189379A (enExample) |
| PT (1) | PT69093A (enExample) |
| SE (1) | SE7900318L (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1125762A (en) * | 1979-07-13 | 1982-06-15 | Alexander E. Wick | Dihydronicotinic acid derivatives and process for the preparation thereof |
| US4964896A (en) * | 1980-05-12 | 1990-10-23 | Monsanto Company | Certain-2,6-diphenyl-1,4-dihydro-4-oxo-nicotinates which are useful for inducing male sterility in cereal grain plants |
| AU539399B2 (en) * | 1980-05-12 | 1984-09-27 | Zeneca Limited | Substituted oxonicotinates |
| US4714492A (en) * | 1980-05-12 | 1987-12-22 | Rohm And Haas Company | Certain 2-phenyl-4-oxo-nicotinates and their use for inducing male sterility in a cereal grain plant |
| US4936904A (en) * | 1980-05-12 | 1990-06-26 | Carlson Glenn R | Aryl-4-oxonicotinates useful for inducing male sterility in cereal grain plants |
| NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
| JPS5980665A (ja) * | 1982-10-29 | 1984-05-10 | Toyama Chem Co Ltd | 4−オキソ−1,4−ジヒドロニコチン酸誘導体 |
| DE3338846A1 (de) * | 1982-10-29 | 1984-05-03 | Toyama Chemical Co. Ltd., Tokyo | Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben |
| GB8502424D0 (en) * | 1985-01-31 | 1985-03-06 | Pharis R P | Promotion of flowering fruit trees |
| GB9317314D0 (en) * | 1993-08-20 | 1993-10-06 | Smithkline Beecham Corp | Compounds |
| EP2149547A1 (en) * | 2008-07-30 | 2010-02-03 | LEK Pharmaceuticals D.D. | Process for the synthesis of ezetimibe and intermediates useful therefor |
| WO2015099107A1 (ja) | 2013-12-26 | 2015-07-02 | 塩野義製薬株式会社 | 含窒素6員環誘導体およびそれらを含有する医薬組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3907808A (en) * | 1971-05-17 | 1975-09-23 | Sterling Drug Inc | 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives |
| IN142614B (enExample) * | 1974-08-28 | 1977-08-06 | Lilly Co Eli | |
| CA1125762A (en) * | 1979-07-13 | 1982-06-15 | Alexander E. Wick | Dihydronicotinic acid derivatives and process for the preparation thereof |
| DE3338846A1 (de) * | 1982-10-29 | 1984-05-03 | Toyama Chemical Co. Ltd., Tokyo | Neue 4-oxo-1,4-dihydronicotinsaeurederivate und salze derselben, verfahren zu ihrer herstellung und antibakterielle mittel mit einem gehalt derselben |
-
1978
- 1978-12-28 CA CA318,702A patent/CA1110234A/en not_active Expired
-
1979
- 1979-01-11 AU AU43296/79A patent/AU521148B2/en not_active Ceased
- 1979-01-12 IL IL56421A patent/IL56421A/xx unknown
- 1979-01-12 NL NL7900264A patent/NL7900264A/xx not_active Application Discontinuation
- 1979-01-12 FI FI790103A patent/FI790103A7/fi unknown
- 1979-01-15 MC MC791356A patent/MC1239A1/fr unknown
- 1979-01-15 NZ NZ189379A patent/NZ189379A/en unknown
- 1979-01-15 SE SE7900318A patent/SE7900318L/xx unknown
- 1979-01-15 HU HU79HO2130A patent/HU179487B/hu unknown
- 1979-01-16 JP JP233079A patent/JPS54100382A/ja active Pending
- 1979-01-16 LU LU80794A patent/LU80794A1/de unknown
- 1979-01-16 GR GR58105A patent/GR73088B/el unknown
- 1979-01-16 FR FR7900974A patent/FR2415103A1/fr active Granted
- 1979-01-17 KR KR7900120A patent/KR820002111B1/ko not_active Expired
- 1979-01-17 AR AR275201A patent/AR223663A1/es active
- 1979-01-17 AT AT0035079A patent/AT369731B/de not_active IP Right Cessation
- 1979-01-17 PT PT7969093A patent/PT69093A/pt unknown
- 1979-01-17 GB GB7901668A patent/GB2013190B/en not_active Expired
- 1979-01-17 DK DK20279A patent/DK20279A/da not_active Application Discontinuation
- 1979-01-17 ES ES476917A patent/ES476917A1/es not_active Expired
- 1979-01-17 NO NO790165A patent/NO152089C/no unknown
- 1979-01-18 DE DE19792901868 patent/DE2901868A1/de not_active Withdrawn
- 1979-01-18 EP EP79100149A patent/EP0003144B1/de not_active Expired
- 1979-01-30 IE IE113/79A patent/IE47784B1/en unknown
-
1982
- 1982-04-19 US US06/369,778 patent/US4521535A/en not_active Expired - Fee Related
-
1984
- 1984-11-02 US US06/667,528 patent/US4549022A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATA35079A (de) | 1982-06-15 |
| US4521535A (en) | 1985-06-04 |
| FR2415103A1 (fr) | 1979-08-17 |
| FR2415103B1 (enExample) | 1982-11-05 |
| JPS54100382A (en) | 1979-08-08 |
| LU80794A1 (de) | 1980-02-14 |
| PT69093A (en) | 1979-02-01 |
| IE47784B1 (en) | 1984-06-13 |
| SE7900318L (sv) | 1979-07-19 |
| AU521148B2 (en) | 1982-03-18 |
| US4549022A (en) | 1985-10-22 |
| NO152089B (no) | 1985-04-22 |
| EP0003144A2 (de) | 1979-07-25 |
| IL56421A0 (en) | 1979-03-12 |
| IE790113L (en) | 1979-07-18 |
| IL56421A (en) | 1982-08-31 |
| HU179487B (en) | 1982-10-28 |
| EP0003144B1 (de) | 1981-08-05 |
| AT369731B (de) | 1983-01-25 |
| KR820002111B1 (ko) | 1982-11-10 |
| NZ189379A (en) | 1984-07-06 |
| CA1110234A (en) | 1981-10-06 |
| DK20279A (da) | 1979-07-19 |
| NO152089C (no) | 1985-08-14 |
| NL7900264A (nl) | 1979-07-20 |
| AR223663A1 (es) | 1981-09-15 |
| DE2901868A1 (de) | 1979-07-19 |
| AU4329679A (en) | 1979-07-26 |
| NO790165L (no) | 1979-07-19 |
| FI790103A7 (fi) | 1979-07-19 |
| GR73088B (enExample) | 1984-02-01 |
| MC1239A1 (fr) | 1979-10-26 |
| EP0003144A3 (en) | 1979-08-08 |
| GB2013190B (en) | 1982-07-14 |
| GB2013190A (en) | 1979-08-08 |
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