DK542781A - Tricycliske cytosinderivater til anvendelse som laegemidler samt fremgangsmaade til fremstilling heraf - Google Patents
Tricycliske cytosinderivater til anvendelse som laegemidler samt fremgangsmaade til fremstilling herafInfo
- Publication number
- DK542781A DK542781A DK542781A DK542781A DK542781A DK 542781 A DK542781 A DK 542781A DK 542781 A DK542781 A DK 542781A DK 542781 A DK542781 A DK 542781A DK 542781 A DK542781 A DK 542781A
- Authority
- DK
- Denmark
- Prior art keywords
- cytosin
- tricyclic
- procedures
- derivatives
- production
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical class NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 2
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Fats And Perfumes (AREA)
- Lubricants (AREA)
- Treatment Of Water By Ion Exchange (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803046366 DE3046366A1 (de) | 1980-12-09 | 1980-12-09 | Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK542781A true DK542781A (da) | 1982-06-10 |
Family
ID=6118700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK542781A DK542781A (da) | 1980-12-09 | 1981-12-08 | Tricycliske cytosinderivater til anvendelse som laegemidler samt fremgangsmaade til fremstilling heraf |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4585772A (da) |
| EP (1) | EP0053767B1 (da) |
| JP (1) | JPS57122085A (da) |
| AT (1) | ATE9350T1 (da) |
| AU (1) | AU549240B2 (da) |
| CA (1) | CA1184910A (da) |
| DE (2) | DE3046366A1 (da) |
| DK (1) | DK542781A (da) |
| ES (2) | ES507807A0 (da) |
| FI (1) | FI813912L (da) |
| HU (1) | HU191038B (da) |
| IL (1) | IL64472A0 (da) |
| ZA (1) | ZA818499B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4713383A (en) * | 1984-10-01 | 1987-12-15 | Ciba-Geigy Corporation | Triazoloquinazoline compounds, and their methods of preparation, pharmaceutical compositions, and uses |
| US4831013A (en) * | 1986-03-20 | 1989-05-16 | Ciba-Geigy Corporation | 2-substituted-e-fused-[1,2,4]triazolo[1,5-c]pyrimidines, pharmaceutical compositions, and uses thereof |
| FR2659329B1 (fr) * | 1990-03-09 | 1994-06-03 | Adir | Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
| US5158953A (en) * | 1991-08-13 | 1992-10-27 | National Science Council | 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof |
| US5212310A (en) * | 1991-12-19 | 1993-05-18 | Neurogen Corporation | Certain aryl fused imidazopyrimidines; a new class of GABA brain receptor ligands |
| US5539260A (en) * | 1994-08-29 | 1996-07-23 | Ford Motor Company | Method and apparatus for an automotive security system which permits engine running prior to code comparison |
| US5637929A (en) * | 1996-01-16 | 1997-06-10 | Ford Motor Company | Method and apparatus for enhanced vehicle protection |
| US7375125B2 (en) * | 1999-08-04 | 2008-05-20 | Ore Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
| JP2003528810A (ja) * | 1999-08-04 | 2003-09-30 | ミレニアム ファーマスーティカルズ インク | メラノコルチン−４受容体結合化合物及びその使用方法 |
| GB2454549B (en) * | 2007-09-25 | 2009-09-23 | Medical & Pharm Ind Tech & Dev | Uses of 2-[piperidinyl]methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one for providing an anti-allergic effect and histamine H1 receptor antagonism effect |
| WO2013177053A1 (en) * | 2012-05-21 | 2013-11-28 | Allergan, Inc. | Pyrimidino [1, 2 -c] quinazolinone derivatives as tyrosine kinases inhibitors |
| BR112014031730B1 (pt) | 2012-06-18 | 2023-05-16 | Dart Neuroscience (Cayman) Ltd | Compostos ou sais farmaceuticamente aceitáveis dos mesmos e seu uso |
| JP6420400B2 (ja) * | 2017-04-12 | 2018-11-07 | ダート・ニューロサイエンス・（ケイマン）・リミテッド | 置換ピリジンアゾロピリミジン−５−（６ｈ）−オン化合物 |
| CN108178759B (zh) * | 2018-01-05 | 2020-06-09 | 上海瑞纷医药科技有限责任公司 | 一种α-肾上腺素受体拮抗剂的合成方法 |
| GB2575490A (en) * | 2018-07-12 | 2020-01-15 | Recordati Ind Chimica E Farmaceutica Spa | P2X3 receptor antagonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3329679A (en) * | 1965-12-22 | 1967-07-04 | American Home Prod | Fused-ring imidazoquinazolines, pyrimidoquinazolines and related compounds |
| US3594379A (en) * | 1968-09-16 | 1971-07-20 | Sandoz Ag | 2,3-dihydroimidazo(1,2-c)quinazolines |
| CA986932A (en) * | 1970-08-27 | 1976-04-06 | Shigeho Inaba | Process for preparing quinazoline derivatives |
| IE51802B1 (en) * | 1979-12-03 | 1987-04-01 | Fujisawa Pharmaceutical Co | Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them |
-
1980
- 1980-12-09 DE DE19803046366 patent/DE3046366A1/de not_active Withdrawn
-
1981
- 1981-11-27 EP EP81109949A patent/EP0053767B1/de not_active Expired
- 1981-11-27 AT AT81109949T patent/ATE9350T1/de not_active IP Right Cessation
- 1981-11-27 DE DE8181109949T patent/DE3166084D1/de not_active Expired
- 1981-12-07 IL IL64472A patent/IL64472A0/xx unknown
- 1981-12-07 FI FI813912A patent/FI813912L/fi not_active Application Discontinuation
- 1981-12-07 CA CA000391607A patent/CA1184910A/en not_active Expired
- 1981-12-07 AU AU78317/81A patent/AU549240B2/en not_active Ceased
- 1981-12-08 DK DK542781A patent/DK542781A/da not_active Application Discontinuation
- 1981-12-08 ZA ZA818499A patent/ZA818499B/xx unknown
- 1981-12-09 ES ES507807A patent/ES507807A0/es active Granted
- 1981-12-09 ES ES507810A patent/ES8400076A1/es not_active Expired
- 1981-12-09 JP JP56197042A patent/JPS57122085A/ja active Pending
- 1981-12-09 HU HU813706A patent/HU191038B/hu unknown
-
1983
- 1983-07-11 US US06/512,582 patent/US4585772A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI813912L (fi) | 1982-06-10 |
| CA1184910A (en) | 1985-04-02 |
| ATE9350T1 (de) | 1984-09-15 |
| DE3166084D1 (en) | 1984-10-18 |
| ES507810A0 (es) | 1983-10-16 |
| ES8300111A1 (es) | 1982-10-01 |
| AU549240B2 (en) | 1986-01-23 |
| AU7831781A (en) | 1982-06-17 |
| EP0053767A1 (de) | 1982-06-16 |
| DE3046366A1 (de) | 1982-07-08 |
| JPS57122085A (en) | 1982-07-29 |
| IL64472A0 (en) | 1982-03-31 |
| ZA818499B (en) | 1982-11-24 |
| EP0053767B1 (de) | 1984-09-12 |
| ES8400076A1 (es) | 1983-10-16 |
| US4585772A (en) | 1986-04-29 |
| HU191038B (en) | 1986-12-28 |
| ES507807A0 (es) | 1982-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |