ES475977A1 - Un procedimiento parala preparacion de derivados de bencil- cicloheptapiridinas - Google Patents

Un procedimiento parala preparacion de derivados de bencil- cicloheptapiridinas

Info

Publication number
ES475977A1
ES475977A1 ES475977A ES475977A ES475977A1 ES 475977 A1 ES475977 A1 ES 475977A1 ES 475977 A ES475977 A ES 475977A ES 475977 A ES475977 A ES 475977A ES 475977 A1 ES475977 A1 ES 475977A1
Authority
ES
Spain
Prior art keywords
derivatives
preparation
cycloheptapyridine
bencil
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES475977A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES475977A1 publication Critical patent/ES475977A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES475977A 1977-12-15 1978-12-13 Un procedimiento parala preparacion de derivados de bencil- cicloheptapiridinas Expired ES475977A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86066677A 1977-12-15 1977-12-15

Publications (1)

Publication Number Publication Date
ES475977A1 true ES475977A1 (es) 1980-03-01

Family

ID=25333744

Family Applications (2)

Application Number Title Priority Date Filing Date
ES475977A Expired ES475977A1 (es) 1977-12-15 1978-12-13 Un procedimiento parala preparacion de derivados de bencil- cicloheptapiridinas
ES481207A Expired ES481207A1 (es) 1977-12-15 1979-06-01 Un procedimiento para l preparacion de derivados de benzoci-cloheptapiridinas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES481207A Expired ES481207A1 (es) 1977-12-15 1979-06-01 Un procedimiento para l preparacion de derivados de benzoci-cloheptapiridinas.

Country Status (14)

Country Link
EP (1) EP0002512B1 (enExample)
JP (1) JPS5495600A (enExample)
AT (1) AT373256B (enExample)
AU (1) AU4225778A (enExample)
DE (1) DE2862381D1 (enExample)
DK (1) DK561478A (enExample)
ES (2) ES475977A1 (enExample)
FI (1) FI783790A7 (enExample)
GR (1) GR66834B (enExample)
IE (1) IE48040B1 (enExample)
IL (1) IL56112A0 (enExample)
IT (1) IT1110891B (enExample)
NO (1) NO784208L (enExample)
PT (1) PT68882A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4252810A (en) * 1978-11-15 1981-02-24 Merck & Co., Inc. 9,10-Dihydro-4H-benzo[4,5]cyclohepta [1,2-b]thiophen-4,9-imines
JP2766266B2 (ja) * 1988-06-20 1998-06-18 協和醗酵工業株式会社 ピリジン誘導体およびその中間体
US5064831A (en) * 1990-09-14 1991-11-12 Bristol-Myers Squibb Co. Naphthothiophenimines for treating neuronal disorders caused by ischemia

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794904A (fr) * 1972-02-04 1973-08-02 Roussel Uclaf Nouveaux derives du dibenzocycloheptene et leur preparation

Also Published As

Publication number Publication date
PT68882A (en) 1979-01-01
NO784208L (no) 1979-06-18
IE782466L (en) 1979-06-15
IL56112A0 (en) 1979-03-12
AT373256B (de) 1984-01-10
IT1110891B (it) 1986-01-06
EP0002512B1 (en) 1984-02-22
IE48040B1 (en) 1984-09-05
DE2862381D1 (en) 1984-03-29
DK561478A (da) 1979-07-31
AU4225778A (en) 1979-06-21
FI783790A7 (fi) 1979-06-16
EP0002512A1 (en) 1979-06-27
JPS6213957B2 (enExample) 1987-03-30
GR66834B (enExample) 1981-05-04
ES481207A1 (es) 1980-02-16
JPS5495600A (en) 1979-07-28
ATA892078A (de) 1983-05-15
IT7852319A0 (it) 1978-12-15

Similar Documents

Publication Publication Date Title
ES2000842A6 (es) Un procedimiento para la preparacion de analogos semisinteticos de compactina y mevinolina
ES476955A1 (es) Un procedimiento para la preparacion de derivados se imida- zoquinazolina.
ES2186672T3 (es) Procedimiento para la produccion de derivados 13-eter de milbemicinas, e intermedios de los mismos.
ES482918A1 (es) Procedimiento para la preparacion de derivados de indanilo
KR920701177A (ko) 3-아릴옥사졸리디논 유도체, 그의 제조 방법 및 그의 치료 용도
FR2398065A1 (enExample)
ES8801174A1 (es) Un procedimiento para la preparacion de derivados de tetrahidronaftaleno.
ES2058177T3 (es) Nuevos derivados de alcanosulfonanilida, procedimientos para su preparacion y composiciones farmaceuticas que los contienen.
SE8305918D0 (sv) Mellanprodukter for framstellning av bensimidazolderivat
MX9202975A (es) Nuevos compuestos biciclicos y sus sales farmaceuticamente aceptables y procedimiento para su preparacion.
ES473925A1 (es) Un procedimiento para la preparacion de un oligopeptido
ES8704486A1 (es) Procedimiento de preparar derivados rodaninicos.
ES475977A1 (es) Un procedimiento parala preparacion de derivados de bencil- cicloheptapiridinas
ES480671A1 (es) Un procedimiento para la preparacion de nuevos derivados de quinazolina.
ES8306742A1 (es) "un procedimiento para la preparacion de 4-(4-imidazolil)-piridinas 2-sustituidas".
ES476385A1 (es) Un procedimiento para preparar derivados de transpirindina
RU94033098A (ru) Способ производных 1-замещенного-5/4h/-тетразолинона
DK630187A (da) Imidazolderivater samt fremgangsmaade til fremstilling deraf
ES483284A1 (es) Un procedimiento para la preparacion de nuevas dibenzo (a,d)ciclohepten-5,10-iminas sustituidas
AR247197A1 (es) Procedimiento para preparacion de nuevos compuestos broncoespasmoliticos
ES455721A1 (es) Procedimiento para la preparacion de una nueva sal de pipe- raziniluracilo.
ES8301480A1 (es) Un procedimiento para la produccion de derivados de 11-piperazinil-5h--pirrolo 1,2-b, 1,2,5 benzotriazepina.
ES483985A1 (es) Procedimiento para preparar alfa-aril-alfa,alfa-bis(omega- (amino disustituido)alquil)acetamidas
ES8100304A1 (es) Un procedimiento para preparar derivados de indol policiclicos
ES8304920A1 (es) Un procedimiento para preparar derivados de n-acil-n-hidroxi-a minoacidos.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202