ES471060A1 - Un procedimiento de preparacion de hexahidro-benzopiran (3,2-c) piridinas - Google Patents

Un procedimiento de preparacion de hexahidro-benzopiran (3,2-c) piridinas

Info

Publication number
ES471060A1
ES471060A1 ES471060A ES471060A ES471060A1 ES 471060 A1 ES471060 A1 ES 471060A1 ES 471060 A ES471060 A ES 471060A ES 471060 A ES471060 A ES 471060A ES 471060 A1 ES471060 A1 ES 471060A1
Authority
ES
Spain
Prior art keywords
hydrogen
halogen
pyridines
substituted
hexahydrobenzopyrano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471060A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
LIPHA Liyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7719360A external-priority patent/FR2395270A1/fr
Priority claimed from FR7816376A external-priority patent/FR2427336A2/fr
Application filed by LIPHA SAS, LIPHA Liyonnaise Industrielle Pharmaceutique filed Critical LIPHA SAS
Publication of ES471060A1 publication Critical patent/ES471060A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Un procedimiento de preparación de hexahidro-benzopiran[3,2-C]piridinas sustituidas de la fórmula **(Fórmula)** en la que R es hidrógeno o un radical alcohilo inferior saturado o insaturado, lineal o ramificado, aralcohilo, acilo, dialcohilaminoalcohilo, alcohilcarbonilo, alcoxi-carbonilo, halogenoalcoxicarbonilo o arilo; R1 es hidrógeno, un halógeno o un radical alcoxi inferior; R2 es hidrógeno o un halógeno; R3 es hidrógeno, un halógeno, un radical alcohilo inferior, alcoxi, nitro, amino o forma naftaleno con R4 y el ciclo bencénico; R4 es hidrógeno, un halógeno o forma naftaleno con R3 y el ciclo bencénico; R5 es hidrógeno, un radical alcohilo inferior o arilalcohilo, caracterizado porque se adiciona una piperidona-4-substituida.
ES471060A 1977-06-24 1978-06-23 Un procedimiento de preparacion de hexahidro-benzopiran (3,2-c) piridinas Expired ES471060A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7719360A FR2395270A1 (fr) 1977-06-24 1977-06-24 Hexahydro benzopyrano (3,2-c) pyridines substituees, utilisables notamment comme medicaments
FR7816376A FR2427336A2 (fr) 1978-06-01 1978-06-01 Hexahydro benzopyrano (3,2-c) pyridines substituees utilisables notamment comme medicament

Publications (1)

Publication Number Publication Date
ES471060A1 true ES471060A1 (es) 1979-01-01

Family

ID=26220098

Family Applications (1)

Application Number Title Priority Date Filing Date
ES471060A Expired ES471060A1 (es) 1977-06-24 1978-06-23 Un procedimiento de preparacion de hexahidro-benzopiran (3,2-c) piridinas

Country Status (22)

Country Link
US (1) US4201783A (es)
EP (1) EP0000306B1 (es)
JP (1) JPS5412399A (es)
AR (1) AR225732A1 (es)
AT (1) AT356662B (es)
AU (1) AU519417B2 (es)
CA (1) CA1098519A (es)
CS (1) CS207624B2 (es)
DD (1) DD137441A5 (es)
DE (1) DE2860016D1 (es)
DK (1) DK158311C (es)
ES (1) ES471060A1 (es)
HU (1) HU177341B (es)
IE (1) IE46999B1 (es)
IL (1) IL54953A (es)
IN (1) IN151192B (es)
IT (1) IT1097257B (es)
MX (1) MX5090E (es)
NO (1) NO150205C (es)
NZ (1) NZ187629A (es)
SU (1) SU931108A3 (es)
YU (1) YU40338B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2522666A1 (en) * 2003-04-18 2004-10-28 Pharmacia & Upjohn Company Llc Combination therapies for chronic obstructive pulmonary disease (copd)
SG185102A1 (en) 2010-04-30 2012-12-28 Basf Se Polyether polyols, process for preparing polyether polyols and their use for producing polyurethanes
US9434975B2 (en) * 2011-03-30 2016-09-06 3M Innovative Properties Company Fluorogenic or fluorophoric compounds and uses thereof
JP7209475B2 (ja) 2018-04-09 2023-01-20 日産自動車株式会社 電池の製造方法
CN111617254B (zh) * 2020-07-02 2022-04-26 中国人民解放军军事科学院军事医学研究院 降低mysm1含量或活性的物质在治疗抑郁症中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3549641A (en) * 1966-06-28 1970-12-22 Warner Lambert Pharmaceutical Pyrano pyridines and process for their production
US3673194A (en) * 1970-05-04 1972-06-27 American Cyanamid Co DERIVATIVES OF 1,4,4a,9b-TETRAHYDRO-8,9b-DIMETHYL-2-PHENYL-1,4-ETHANOBENZOFURO {8 3,2-C{9 PYRIDINE-3(2H), 10-DIONE
US4033968A (en) * 1976-04-14 1977-07-05 Merck & Co., Inc. Diazatetracyclododecanes

Also Published As

Publication number Publication date
NO782184L (no) 1978-12-28
IL54953A0 (en) 1978-08-31
IL54953A (en) 1984-06-29
DK281978A (da) 1978-12-25
NO150205B (no) 1984-05-28
CA1098519A (fr) 1981-03-31
JPS5412399A (en) 1979-01-30
IN151192B (es) 1983-03-05
HU177341B (en) 1981-09-28
YU40338B (en) 1985-12-31
IT1097257B (it) 1985-08-31
IE781239L (en) 1978-12-24
JPS633866B2 (es) 1988-01-26
AU519417B2 (en) 1981-12-03
EP0000306B1 (fr) 1980-05-28
AT356662B (de) 1980-05-12
CS207624B2 (en) 1981-08-31
IE46999B1 (en) 1983-11-30
SU931108A3 (ru) 1982-05-23
EP0000306A1 (fr) 1979-01-10
MX5090E (es) 1983-03-15
US4201783A (en) 1980-05-06
AU3746378A (en) 1980-01-03
DD137441A5 (de) 1979-09-05
NZ187629A (en) 1981-03-16
DK158311B (da) 1990-04-30
YU143878A (en) 1982-10-31
DE2860016D1 (en) 1980-10-16
NO150205C (no) 1984-09-05
IT7824705A0 (it) 1978-06-19
ATA464478A (de) 1979-10-15
DK158311C (da) 1990-10-08
AR225732A1 (es) 1982-04-30

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