ES468363A1 - Proceso para la fabricacion de un preparado destinado al tra-tamiento de herpes-zoster. - Google Patents
Proceso para la fabricacion de un preparado destinado al tra-tamiento de herpes-zoster.Info
- Publication number
- ES468363A1 ES468363A1 ES468363A ES468363A ES468363A1 ES 468363 A1 ES468363 A1 ES 468363A1 ES 468363 A ES468363 A ES 468363A ES 468363 A ES468363 A ES 468363A ES 468363 A1 ES468363 A1 ES 468363A1
- Authority
- ES
- Spain
- Prior art keywords
- herpes
- treatment
- manufacture
- preparation
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
- A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Abstract
Proceso para la fabricación de un preparado destinado al tratamiento de Herpes-Zoster, caracterizado por el hecho de inocular cultivos de células con virus variólicos o para-variólicos (Familia : Poxviridae), y en el punto álgido de la multiplicación de los virus, se recolectan y depuran dichos virus; la cosecha de virus depurada, se ajusta a un título o contenido de aproximadamente 5 x 10 6 hasta 5 x 10 8 ID50/ml de suspensión de utilización del virus; mediante radiaciones con rayos gamma, se efectúa una destrucción selectiva de los ácidos nucleínicos del virus sin que ello implique la destrucción o modificación de las restantes estructuras virales, en especial de las estructuras de superficie del virus, de la proteína del virus y de las sustancias envolventes; y a continuación en su caso, se procesa y trata el virus con estabilizadores y/o otras sustancias auxiliares, hasta conseguir un preparado para aplicación intraperitoneal o local.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772714665 DE2714665A1 (de) | 1977-04-01 | 1977-04-01 | Praeparat zur behandlung von herpes zoster und anderen herpes-infektionen, sowie verfahren zu seiner herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES468363A1 true ES468363A1 (es) | 1978-12-01 |
Family
ID=6005417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES468363A Expired ES468363A1 (es) | 1977-04-01 | 1978-03-30 | Proceso para la fabricacion de un preparado destinado al tra-tamiento de herpes-zoster. |
Country Status (22)
Country | Link |
---|---|
US (1) | US4191745A (es) |
JP (1) | JPS53124615A (es) |
AT (1) | AT359639B (es) |
AU (1) | AU521512B2 (es) |
BE (1) | BE865381A (es) |
CA (1) | CA1095407A (es) |
CH (1) | CH639281A5 (es) |
DD (1) | DD136701A5 (es) |
DE (1) | DE2714665A1 (es) |
DK (1) | DK152745C (es) |
ES (1) | ES468363A1 (es) |
FR (1) | FR2385402A1 (es) |
GB (1) | GB1586129A (es) |
HU (1) | HU180260B (es) |
IL (1) | IL54370A (es) |
NL (1) | NL7803503A (es) |
NO (1) | NO148874C (es) |
NZ (1) | NZ186705A (es) |
PH (1) | PH20267A (es) |
PT (1) | PT67829B (es) |
SE (1) | SE7803615L (es) |
ZA (1) | ZA781505B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4315914A (en) * | 1980-04-04 | 1982-02-16 | Seiji Arakawa | Pharmaceutical compositions useful as cellular immunopotentiator and antitumor agent and process for production thereof |
DE3122669A1 (de) * | 1980-06-12 | 1982-02-11 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | "verfahren zur herstellung von neuen mutanten von herpes simplex-viren typ 1 und typ 2" |
EP0227441B1 (en) * | 1985-12-20 | 1991-05-15 | E.I. Du Pont De Nemours And Company | Preparation of tablets of microbiological substances |
JPH02115129A (ja) * | 1988-10-21 | 1990-04-27 | Kokuritsu Yobou Eisei Kenkyusho | 抗ウィルス剤 |
CA2139515C (en) | 1992-07-17 | 2008-12-23 | Gary B. Calandra | Method for preventing zoster or alleviating varicella related post-herpetic neuralgia |
DE10122451A1 (de) * | 2000-07-11 | 2002-04-04 | Bayer Ag | Verwendung von Stämmen des Parapoxvirus ovis zur Herstellung von antiviralen Arzneimitteln und Arzneimitteln gegen Krebs |
AU2001270631B2 (en) * | 2000-07-11 | 2005-07-07 | Bayer Aktiengesellschaft | Use of strains of the parapox ovis virus for producing antiviral pharmaceuticals and anticancer pharmaceuticals |
AU2001285827B2 (en) * | 2000-07-11 | 2006-11-30 | Aicuris Gmbh & Co. Kg | Use of strains of the parapox ovis virus against organ fibrosis |
US7628980B2 (en) * | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
NZ524661A (en) * | 2000-11-23 | 2005-03-24 | Bavarian Nordic As | Modified vaccinia ankara virus variant |
US7097842B2 (en) * | 2000-11-23 | 2006-08-29 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
EP1839672A3 (en) * | 2002-04-19 | 2007-11-21 | Bavarian Nordic A/S | Modified vaccinia virus Ankara for the vaccination of neonates |
KR101044538B1 (ko) * | 2002-09-05 | 2011-06-27 | 버베리안 노딕 에이/에스 | 무혈청 조건하에서 일차세포의 배양 및 바이러스의 증식방법 |
UA112970C2 (uk) * | 2010-08-05 | 2016-11-25 | Мерк Шарп Енд Доме Корп. | Інактивований вірус вітряної віспи, спосіб його одержання і застосування |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE787901A (fr) * | 1971-09-11 | 1972-12-18 | Freistaat Bayern Represente Pa | Vaccin antivariolique |
DE2215728C3 (de) * | 1972-03-30 | 1979-02-15 | Stickl, Helmut, Prof. Dr.Med., 8033 Krailling | Arzneimittel zur Behandlung von Herpes simplex |
ZA754725B (en) * | 1974-08-01 | 1976-06-30 | H Stickl | Preparation for the treatment of infectious diseases, method for the manufacture thereof, and its use |
-
1977
- 1977-04-01 DE DE19772714665 patent/DE2714665A1/de not_active Withdrawn
-
1978
- 1978-03-14 ZA ZA00781505A patent/ZA781505B/xx unknown
- 1978-03-16 NZ NZ186705A patent/NZ186705A/xx unknown
- 1978-03-17 PH PH20894A patent/PH20267A/en unknown
- 1978-03-21 AU AU34359/78A patent/AU521512B2/en not_active Expired
- 1978-03-28 BE BE186326A patent/BE865381A/xx not_active IP Right Cessation
- 1978-03-28 IL IL54370A patent/IL54370A/xx unknown
- 1978-03-28 PT PT67829A patent/PT67829B/pt unknown
- 1978-03-29 CA CA299,915A patent/CA1095407A/en not_active Expired
- 1978-03-29 US US05/891,206 patent/US4191745A/en not_active Expired - Lifetime
- 1978-03-30 SE SE7803615A patent/SE7803615L/xx unknown
- 1978-03-30 GB GB12468/78A patent/GB1586129A/en not_active Expired
- 1978-03-30 ES ES468363A patent/ES468363A1/es not_active Expired
- 1978-03-31 CH CH351178A patent/CH639281A5/de not_active IP Right Cessation
- 1978-03-31 NO NO781147A patent/NO148874C/no unknown
- 1978-03-31 NL NL7803503A patent/NL7803503A/xx not_active Application Discontinuation
- 1978-03-31 DK DK143778A patent/DK152745C/da not_active IP Right Cessation
- 1978-03-31 HU HU78MA2973A patent/HU180260B/hu not_active IP Right Cessation
- 1978-03-31 FR FR7809405A patent/FR2385402A1/fr active Granted
- 1978-03-31 AT AT227578A patent/AT359639B/de not_active IP Right Cessation
- 1978-03-31 DD DD78204523A patent/DD136701A5/xx not_active IP Right Cessation
- 1978-04-01 JP JP3874378A patent/JPS53124615A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
CA1095407A (en) | 1981-02-10 |
JPS53124615A (en) | 1978-10-31 |
GB1586129A (en) | 1981-03-18 |
AU3435978A (en) | 1979-09-27 |
DK152745C (da) | 1988-09-26 |
SE7803615L (sv) | 1978-10-02 |
HU180260B (en) | 1983-02-28 |
US4191745A (en) | 1980-03-04 |
FR2385402B1 (es) | 1981-05-29 |
IL54370A0 (en) | 1978-06-15 |
NO148874B (no) | 1983-09-26 |
PH20267A (en) | 1986-11-14 |
DD136701A5 (de) | 1979-07-25 |
PT67829B (de) | 1979-09-27 |
AU521512B2 (en) | 1982-04-08 |
NL7803503A (nl) | 1978-10-03 |
CH639281A5 (de) | 1983-11-15 |
ZA781505B (en) | 1979-03-28 |
IL54370A (en) | 1980-11-30 |
NZ186705A (en) | 1980-04-28 |
NO148874C (no) | 1984-01-11 |
AT359639B (de) | 1980-11-25 |
DK143778A (da) | 1978-10-02 |
BE865381A (fr) | 1978-07-17 |
JPS6339575B2 (es) | 1988-08-05 |
ATA227578A (de) | 1980-04-15 |
DK152745B (da) | 1988-05-09 |
NO781147L (no) | 1978-10-03 |
PT67829A (de) | 1978-04-01 |
DE2714665A1 (de) | 1978-10-05 |
FR2385402A1 (fr) | 1978-10-27 |
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