ATE116637T1 - Sulfonische stilbenderivate zur behandlung von viruserkrankungen. - Google Patents

Sulfonische stilbenderivate zur behandlung von viruserkrankungen.

Info

Publication number
ATE116637T1
ATE116637T1 AT91300914T AT91300914T ATE116637T1 AT E116637 T1 ATE116637 T1 AT E116637T1 AT 91300914 T AT91300914 T AT 91300914T AT 91300914 T AT91300914 T AT 91300914T AT E116637 T1 ATE116637 T1 AT E116637T1
Authority
AT
Austria
Prior art keywords
sulfonic
treatment
virus diseases
stilben derivatives
stilben
Prior art date
Application number
AT91300914T
Other languages
English (en)
Inventor
Alan D Cardin
Stanley A Tyms
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE116637T1 publication Critical patent/ATE116637T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/30—Isothiocyanates containing at least two isothiocyanate groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/16—Isothiocyanates
    • C07C331/28—Isothiocyanates having isothiocyanate groups bound to carbon atoms of six-membered aromatic rings
AT91300914T 1991-02-05 1991-02-05 Sulfonische stilbenderivate zur behandlung von viruserkrankungen. ATE116637T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91300914A EP0498095B1 (de) 1991-02-05 1991-02-05 Sulfonische Stilbenderivate zur Behandlung von Viruserkrankungen

Publications (1)

Publication Number Publication Date
ATE116637T1 true ATE116637T1 (de) 1995-01-15

Family

ID=8208186

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91300914T ATE116637T1 (de) 1991-02-05 1991-02-05 Sulfonische stilbenderivate zur behandlung von viruserkrankungen.

Country Status (11)

Country Link
US (3) US5494932A (de)
EP (1) EP0498095B1 (de)
JP (1) JPH04338329A (de)
KR (1) KR0185683B1 (de)
AT (1) ATE116637T1 (de)
AU (1) AU652413B2 (de)
DE (1) DE69106493T2 (de)
DK (1) DK0498095T3 (de)
GR (1) GR3014998T3 (de)
IE (1) IE65161B1 (de)
ZA (1) ZA92669B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5276182A (en) * 1990-07-09 1994-01-04 The Dow Chemical Company Process for preparing polyurea oligomers
US5670144A (en) * 1990-07-09 1997-09-23 Merrell Pharmaceuticals Inc. Anti-herpes virus and cytomegalovirus polyester oligomers
DE69106493T2 (de) * 1991-02-05 1995-06-29 Merrell Dow Pharma Sulfonische Stilbenderivate zur Behandlung von Viruserkrankungen.
US5424063A (en) * 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process
CA2130360C (en) * 1992-02-20 1998-06-09 Allan D. Cardin Sulfonic acid derivatives in the treatment of viral diseases
IL112174A (en) * 1994-01-03 1999-05-09 Merrell Dow Pharma Oligomers of polythioureas pharmaceutical compositions containing them and a process for their preparation
CN1163401A (zh) * 1996-02-13 1997-10-29 李占元 全自动血球计数仪试剂及配制方法
DE69830751T2 (de) * 1997-04-10 2006-05-18 Pharmacia & Upjohn Co. Llc, Kalamazoo Polyaromatische Verbindungen zur Behandlung von Herpes-Infektionen
US7105552B2 (en) * 1998-05-08 2006-09-12 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6624197B1 (en) 1998-05-08 2003-09-23 Calyx Therapeutics, Inc. Diphenylethylene compounds
US6331633B1 (en) 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6245814B1 (en) 1998-05-08 2001-06-12 Calyx Therapeutics, Inc. Diphenylethylene compounds
US6310073B1 (en) * 1998-07-28 2001-10-30 Queen's University At Kingston Methods and compositions to treat glycosaminoglycan-associated molecular interactions
US7407978B2 (en) * 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6525093B1 (en) 1999-11-08 2003-02-25 Calyx Therapeutics Inc. Compounds to treat diabetes and associated conditions
US20020002200A1 (en) * 2000-02-04 2002-01-03 Bishwagit Nag Novel diphenylethylene compounds
US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20080108825A1 (en) * 1999-11-08 2008-05-08 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
WO2001038530A1 (fr) * 1999-11-24 2001-05-31 Takeda Chemical Industries, Ltd. Utilisation d'un gene associe a une maladie
US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
NZ520754A (en) * 2000-02-10 2004-02-27 Panacos Pharmaceuticals Inc Identifying compounds that disrupt formation of critical gp41 six-helix bundle and conformations necessary for HIV entry thereby blocking virus entry to the cell
DE102008001811A1 (de) * 2008-05-15 2009-11-19 Beiersdorf Ag Kosmetische Zubereitungen zur Verminderung von Schweißgeruch mit ABCC-Modulatoren
US10723834B1 (en) * 2018-04-13 2020-07-28 The United States Of America, As Represented By The Secretary Of The Navy Low melting and low viscosity thermoset matrix resins from the Z configuration of polyhydroxy stilbenes
US20220016068A1 (en) * 2018-11-22 2022-01-20 Université de Nantes Disulfonate stilbenes for use in the treatment of proliferative diseases

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE660945A (de) * 1964-03-12 1965-07-01
US4328244A (en) * 1980-05-21 1982-05-04 The Dow Chemical Company Novel (((substituted-phenyl)methyl)amino)benzenesulfonic acids and pharmaceutically-acceptable salts thereof
US4349568A (en) * 1980-06-12 1982-09-14 The Dow Chemical Company Sulfur-substituted diphenyl ethers having antiviral activity
US4435394A (en) * 1981-12-17 1984-03-06 Shionogi & Co., Ltd. 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections
DE3530718A1 (de) * 1985-08-28 1987-03-12 Madaus & Co Dr Methylendioxyphenanthren- und -stilbenderivate, verfahren zur herstellung derselben und arzneimittel, die diese enthalten
US4820452A (en) * 1985-10-16 1989-04-11 Ciba-Geigy Corporation Bechamp reduction of DNS to DAS using H2 SO4 and trace of HOAc
DE3666810D1 (en) * 1985-10-16 1989-12-14 Ciba Geigy Ag Bechamp reduction of dns to das using h2so4 and trace of hoac
DE3626309A1 (de) * 1986-08-02 1988-02-18 Stockhausen Chem Fab Gmbh Antivirusmittel
US5276182A (en) * 1990-07-09 1994-01-04 The Dow Chemical Company Process for preparing polyurea oligomers
US5124149A (en) * 1990-11-07 1992-06-23 The United States Of America As Represented By The Secretary Of Agriculture Compositions and methods for biocontrol using fluorescent brighteners
DE69106493T2 (de) * 1991-02-05 1995-06-29 Merrell Dow Pharma Sulfonische Stilbenderivate zur Behandlung von Viruserkrankungen.
US5424063A (en) * 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process

Also Published As

Publication number Publication date
US5672625A (en) 1997-09-30
US5932614A (en) 1999-08-03
EP0498095B1 (de) 1995-01-04
US5494932A (en) 1996-02-27
ZA92669B (en) 1992-11-25
GR3014998T3 (en) 1995-05-31
AU652413B2 (en) 1994-08-25
KR0185683B1 (ko) 1999-05-01
IE920360A1 (en) 1992-08-12
EP0498095A1 (de) 1992-08-12
DE69106493T2 (de) 1995-06-29
IE65161B1 (en) 1995-10-04
DE69106493D1 (de) 1995-02-16
AU1062092A (en) 1992-08-13
KR920016090A (ko) 1992-09-24
JPH04338329A (ja) 1992-11-25
DK0498095T3 (da) 1995-06-19

Similar Documents

Publication Publication Date Title
ATE116637T1 (de) Sulfonische stilbenderivate zur behandlung von viruserkrankungen.
ATE165345T1 (de) Sulfonsaeurederivate zur behandlung von viruserkrankungen
ATE68697T1 (de) Verwendung von azolylmethyloxiranen zur bekaempfung von viralen erkrankungen.
DE3881299D1 (de) Retinoide zur behandlung lichtgeschaedigter haut.
DK156098C (da) Thixotropt middel til brug ved fraktionering af blod
DE3780016D1 (de) Pharmazeutisches praeparat mit 3'-desoxythymidin-2'-en(3'-desoxy-2',3'-didehydrothymidin) zur behandlung von patienten mit retroviralen infektionen.
ES2123048T3 (es) Analogos de nucleosidos antiviricos.
DE3751772T2 (de) Impfstoff zur behandlung von hsv
DE3767308D1 (de) Verwendung von sulfonamidderivaten zur herstellung eines antivirusmittels.
ES2058203T3 (es) Derivados del acido pirocatequincarboxilico, su obtencion y empleo como substancias activas para medicamentos.
ATE88752T1 (de) Inaktivierung von human immunodeficiency virus (hiv) in proteinhaltigen loesungen durch phenole.
DE69025967T2 (de) Aryl- oder Heteroaryl-1-alkyl-pyrrol-2-carbonsäure-Derivate, zur Behandlung von durch Interleukin-1 hervorgerufenen Erkrankungen
DK0576506T3 (da) Anvendelse af benzimidazol-anthelmintikum ved behandling af mikrosporidial-infektioner
ATE26267T1 (de) Pyrimidin-derivate, ausgestattet mit antiviraler wirkung.
ATE255417T1 (de) Verwendung von bradykinin-antagonisten zur behandlung von viruserkrankungen
SE7904840L (sv) Antiviralt verksamma t-rna-preparat
DE69210737D1 (de) Verwendung von L-2-Oxothiazolidine-4-Carboxylate zur Herstellung eines Arzneimittels zur Behandlung von latenten HIV-Infektionen
DE69422980D1 (de) Extrakte von Piliostigma thonningii, deren Verwendung und diese enthaltende Zubereitungen
DE3883754T2 (de) Mittel zur prophylaxe und behandlung von viralen infektionskrankheiten.
ES2108254T3 (es) Composicion del inhibidor de infeccion con virus del sida.
WO1988008707A3 (en) Rubradirin derivatives for treatment of hiv infection
DE343258T1 (de) Mittel zur prophylaxe und behandlung von viralen infektionskrankheiten.
BG50888A1 (en) TRIALKOXYPHOSPHASO-1-/n-NITROPHENYIL/-1-CHLOR-3-PROPANOLS HAVING ANTIVIRAL ACTIVITY

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee