ES467702A1 - Procedimiento para preparar acetamidas. - Google Patents

Procedimiento para preparar acetamidas.

Info

Publication number
ES467702A1
ES467702A1 ES467702A ES467702A ES467702A1 ES 467702 A1 ES467702 A1 ES 467702A1 ES 467702 A ES467702 A ES 467702A ES 467702 A ES467702 A ES 467702A ES 467702 A1 ES467702 A1 ES 467702A1
Authority
ES
Spain
Prior art keywords
acetamides
aryl
bis
alkyl
disubstituted amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES467702A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES467702A1 publication Critical patent/ES467702A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ES467702A 1977-03-11 1978-03-09 Procedimiento para preparar acetamidas. Expired ES467702A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,563 US4107205A (en) 1977-03-11 1977-03-11 α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

Publications (1)

Publication Number Publication Date
ES467702A1 true ES467702A1 (es) 1978-10-16

Family

ID=25107748

Family Applications (1)

Application Number Title Priority Date Filing Date
ES467702A Expired ES467702A1 (es) 1977-03-11 1978-03-09 Procedimiento para preparar acetamidas.

Country Status (22)

Country Link
US (2) US4107205A (es)
JP (1) JPS53121737A (es)
AT (1) AT355557B (es)
AU (1) AU520656B2 (es)
BE (1) BE864822A (es)
CA (1) CA1102339A (es)
CH (1) CH635312A5 (es)
DE (1) DE2810143A1 (es)
DK (1) DK107878A (es)
ES (1) ES467702A1 (es)
FI (1) FI780771A (es)
FR (1) FR2383163A1 (es)
GB (1) GB1580588A (es)
GR (1) GR74125B (es)
IE (1) IE46482B1 (es)
IL (1) IL54252A (es)
NL (1) NL7802672A (es)
NO (1) NO148186C (es)
NZ (1) NZ186653A (es)
PT (1) PT67765A (es)
SE (1) SE7802751L (es)
ZA (1) ZA781429B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217306A (en) * 1978-05-01 1980-08-12 G. D. Searle & Co. α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides
US4560754A (en) * 1983-09-14 1985-12-24 G. D. Searle & Co. Substituted 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
US5097035A (en) * 1984-07-09 1992-03-17 G. D. Searle & Co. Monobasic disobutamide derivatives
US4639524A (en) * 1984-07-09 1987-01-27 G. D. Searle & Co. Monobasic disobutamide derivatives
US4812451A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha.
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4847301A (en) * 1985-11-13 1989-07-11 Pennwalt Corporation Methods of use of α-(aminoalkyl)-arylacetic acid derivatives
US5432284A (en) * 1993-09-08 1995-07-11 G. D. Searle & Co. Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884436A (en) * 1954-08-28 1959-04-28 Nl Combinatie Chem Ind Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) * 1955-06-20 1962-02-20 Upjohn Co Alpha-phenyl-omega-amino-alkanamides
GB796839A (en) * 1955-06-23 1958-06-18 Pharmacia Ab N,n-disubstituted amides of aryl acetic acids
US3078275A (en) * 1956-05-28 1963-02-19 Upjohn Co N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) * 1956-11-19 1959-07-14 Upjohn Co Organic compounds
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
NL124729C (es) * 1963-05-14

Also Published As

Publication number Publication date
CH635312A5 (de) 1983-03-31
BE864822A (fr) 1978-09-13
DK107878A (da) 1978-09-12
NO148186B (no) 1983-05-16
PT67765A (en) 1978-04-01
FI780771A (fi) 1978-09-12
ATA173578A (de) 1979-08-15
SE7802751L (sv) 1978-09-12
US4153797A (en) 1979-05-08
IL54252A (en) 1981-09-13
GB1580588A (en) 1980-12-03
DE2810143A1 (de) 1978-09-14
AU3402578A (en) 1979-09-13
GR74125B (es) 1984-06-06
IE46482B1 (en) 1983-06-29
AU520656B2 (en) 1982-02-18
US4107205A (en) 1978-08-15
ZA781429B (en) 1979-04-25
FR2383163A1 (fr) 1978-10-06
IE780501L (en) 1978-09-11
FR2383163B1 (es) 1981-07-31
NO780869L (no) 1978-09-12
CA1102339A (en) 1981-06-02
AT355557B (de) 1980-03-10
JPS53121737A (en) 1978-10-24
NO148186C (no) 1983-08-24
NL7802672A (nl) 1978-09-13
NZ186653A (en) 1979-11-01
IL54252A0 (en) 1978-06-15

Similar Documents

Publication Publication Date Title
FR2333794A1 (fr) Derives d'acides hydroxy-benzyl-maloniques utilisables comme stabilisants de matieres plastiques
FR2357569A1 (fr) Produits de reaction de l'acide borique et des amines, leur procede de preparation et leur utilisation
SE7708404L (sv) Sett att framstella biologiskt aktiva amider
BG48336A3 (en) Method for preparing of substituted heterocyclic benzamides
ES467702A1 (es) Procedimiento para preparar acetamidas.
FR2325323A1 (fr) Nouvelle composition herbicide a base de n-(3,4-dichlorophenyl)-n',n'-dimethyl-thiouree
FR2222097A1 (es)
FR2368470B1 (fr) Procede de dimerisation d'acrylonitrile en dinitrile lineaire en c6
ES8401930A1 (es) Un procedimiento para preparar derivados de amida del acido nitrobenzoico.
SE7709913L (sv) Sett att framstella penta peptider
FI902321A0 (fi) Butensyraderivat.
PT994840E (pt) Processo para a preparacao de 1-aril-3-ciclopropil-1,3-propanodionas
FR2471973B1 (es)
ES8707710A1 (es) Procedimiento para la obtencion de 2-(n-formilamino)-propionitrilo
IE780502L (en) 2-aryl-2-[omega-(diisopropylamino) alkyl]-omega-¹(azabicycloalkyl)-alkanamides¹¹-w-(aza-bicycloalkyl)-alkanamides
ES483985A1 (es) Procedimiento para preparar alfa-aril-alfa,alfa-bis(omega- (amino disustituido)alquil)acetamidas
FR2337553A1 (fr) Acides pyrrolidone-carboxyliques, utiles comme agents anti-ulceres
ES8506586A1 (es) Procedimiento para preparar meta-o para-isopropenil-alfa-alfa-dimetilbencilamina
CA2054821A1 (en) Process for the production of 3-aminocrotononitrile
ES8101889A1 (es) Procedimiento para la obtencion de pastas endoparasiticidas para caballos
GB1338522A (en) Cyanoethylation of aminophenols
CA1273347C (es)
ES8106485A1 (es) Procedimiento para la preparacion de amida de acido 3-ciano-propionico
JPS5388100A (en) New cationic polymer
GB1086399A (en) Novel ª‡-substituted 2-pyridinethioacetamides and a process for their preparation