FI780771A - Alfa-aryl-alfa alfa-bis (omega-(disubstituerad amino)alkyl)-acetamider och liknande foereningar - Google Patents

Alfa-aryl-alfa alfa-bis (omega-(disubstituerad amino)alkyl)-acetamider och liknande foereningar

Info

Publication number
FI780771A
FI780771A FI780771A FI780771A FI780771A FI 780771 A FI780771 A FI 780771A FI 780771 A FI780771 A FI 780771A FI 780771 A FI780771 A FI 780771A FI 780771 A FI780771 A FI 780771A
Authority
FI
Finland
Prior art keywords
alfa
ambylic
acetamider
foereningar
omega
Prior art date
Application number
FI780771A
Other languages
English (en)
Inventor
Jerry Jay Renbarger
Peter K Yonan
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of FI780771A publication Critical patent/FI780771A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI780771A 1977-03-11 1978-03-10 Alfa-aryl-alfa alfa-bis (omega-(disubstituerad amino)alkyl)-acetamider och liknande foereningar FI780771A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,563 US4107205A (en) 1977-03-11 1977-03-11 α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

Publications (1)

Publication Number Publication Date
FI780771A true FI780771A (fi) 1978-09-12

Family

ID=25107748

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780771A FI780771A (fi) 1977-03-11 1978-03-10 Alfa-aryl-alfa alfa-bis (omega-(disubstituerad amino)alkyl)-acetamider och liknande foereningar

Country Status (22)

Country Link
US (2) US4107205A (fi)
JP (1) JPS53121737A (fi)
AT (1) AT355557B (fi)
AU (1) AU520656B2 (fi)
BE (1) BE864822A (fi)
CA (1) CA1102339A (fi)
CH (1) CH635312A5 (fi)
DE (1) DE2810143A1 (fi)
DK (1) DK107878A (fi)
ES (1) ES467702A1 (fi)
FI (1) FI780771A (fi)
FR (1) FR2383163A1 (fi)
GB (1) GB1580588A (fi)
GR (1) GR74125B (fi)
IE (1) IE46482B1 (fi)
IL (1) IL54252A (fi)
NL (1) NL7802672A (fi)
NO (1) NO148186C (fi)
NZ (1) NZ186653A (fi)
PT (1) PT67765A (fi)
SE (1) SE7802751L (fi)
ZA (1) ZA781429B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217306A (en) * 1978-05-01 1980-08-12 G. D. Searle & Co. α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides
US4560754A (en) * 1983-09-14 1985-12-24 G. D. Searle & Co. Substituted 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
US4639524A (en) * 1984-07-09 1987-01-27 G. D. Searle & Co. Monobasic disobutamide derivatives
US5097035A (en) * 1984-07-09 1992-03-17 G. D. Searle & Co. Monobasic disobutamide derivatives
US4812451A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha.
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4847301A (en) * 1985-11-13 1989-07-11 Pennwalt Corporation Methods of use of α-(aminoalkyl)-arylacetic acid derivatives
US5432284A (en) * 1993-09-08 1995-07-11 G. D. Searle & Co. Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884436A (en) * 1954-08-28 1959-04-28 Nl Combinatie Chem Ind Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) * 1955-06-20 1962-02-20 Upjohn Co Alpha-phenyl-omega-amino-alkanamides
GB796839A (en) * 1955-06-23 1958-06-18 Pharmacia Ab N,n-disubstituted amides of aryl acetic acids
US3078275A (en) * 1956-05-28 1963-02-19 Upjohn Co N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) * 1956-11-19 1959-07-14 Upjohn Co Organic compounds
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
NL124729C (fi) * 1963-05-14

Also Published As

Publication number Publication date
US4153797A (en) 1979-05-08
US4107205A (en) 1978-08-15
CA1102339A (en) 1981-06-02
IL54252A0 (en) 1978-06-15
DK107878A (da) 1978-09-12
CH635312A5 (de) 1983-03-31
IE46482B1 (en) 1983-06-29
ES467702A1 (es) 1978-10-16
IL54252A (en) 1981-09-13
GR74125B (fi) 1984-06-06
FR2383163A1 (fr) 1978-10-06
NL7802672A (nl) 1978-09-13
NO780869L (no) 1978-09-12
GB1580588A (en) 1980-12-03
PT67765A (en) 1978-04-01
NO148186C (no) 1983-08-24
FR2383163B1 (fi) 1981-07-31
JPS53121737A (en) 1978-10-24
SE7802751L (sv) 1978-09-12
ATA173578A (de) 1979-08-15
DE2810143A1 (de) 1978-09-14
NZ186653A (en) 1979-11-01
BE864822A (fr) 1978-09-13
NO148186B (no) 1983-05-16
ZA781429B (en) 1979-04-25
AU3402578A (en) 1979-09-13
AT355557B (de) 1980-03-10
IE780501L (en) 1978-09-11
AU520656B2 (en) 1982-02-18

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: G D SEARLE & CO.