ES467474A1 - Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them - Google Patents

Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ES467474A1
ES467474A1 ES467474A ES467474A ES467474A1 ES 467474 A1 ES467474 A1 ES 467474A1 ES 467474 A ES467474 A ES 467474A ES 467474 A ES467474 A ES 467474A ES 467474 A1 ES467474 A1 ES 467474A1
Authority
ES
Spain
Prior art keywords
radical
lower alkoxy
alkoxy radical
substituted
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES467474A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Publication of ES467474A1 publication Critical patent/ES467474A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Abstract

A process for obtaining esters of -benzylaminoalkoxycarboxylic acids of general formula I ** (Formula-01) ** in which R1 is an alkoyl radical having 3 to 6 carbon atoms, R2 is hydrogen or a lower alkoxy radical, R3 is a hydrogen atom, halogen, a lower alkoxy radical, a trifluoromethyl radical, trifluoromethoxy, acetylamino, sulfamido, lower alkoxy aminosulfonyl, di (lower alkoxy) amino sulfonyl, cyano or acyl derived from a low molecular weight carboxylic acid, R4 represents hydrogen or a lower alkoxy radical, X represents a lower alkoxy radical, X represents a lower alkoylene radical having 4 to 10 carbon atoms, and R "is a lower alkoxy radical, a substituted lower alkoxy radical, a phenyl radical or a substituted phenyl radical, in racemic or optically active form, characterized in that a -benzylaminoalkoxycarboxylic acid of general formula II ** (Formula-02) ** is reacted in which it is substituted ntesR1, R2, R3, R4 and X have the meaning given above, or one of its salts with an alkylating agent to obtain the desired ester. (Machine-translation by Google Translate, not legally binding)
ES467474A 1976-03-11 1978-03-01 Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them Expired ES467474A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9782/76A GB1545291A (en) 1976-03-11 1976-03-11 Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ES467474A1 true ES467474A1 (en) 1979-10-16

Family

ID=9878662

Family Applications (2)

Application Number Title Priority Date Filing Date
ES456776A Expired ES456776A1 (en) 1976-03-11 1977-03-11 Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them
ES467474A Expired ES467474A1 (en) 1976-03-11 1978-03-01 Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES456776A Expired ES456776A1 (en) 1976-03-11 1977-03-11 Benzylamino-alkanamides process for their preparation and pharmaceutical compositions containing them

Country Status (10)

Country Link
JP (1) JPS5831336B2 (en)
AU (1) AU517470B2 (en)
BE (1) BE852359A (en)
DE (1) DE2710807C2 (en)
ES (2) ES456776A1 (en)
FR (1) FR2344523A1 (en)
GB (1) GB1545291A (en)
IL (1) IL51644A (en)
NL (1) NL7702560A (en)
PH (1) PH14145A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472627A (en) * 1974-09-10 1977-05-04 Science Union & Cie Benzylaminoalkanoic acids process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IL51644A0 (en) 1977-05-31
AU2315977A (en) 1978-09-14
JPS52111521A (en) 1977-09-19
DE2710807A1 (en) 1977-09-15
AU517470B2 (en) 1981-08-06
DE2710807C2 (en) 1982-04-22
ES456776A1 (en) 1978-06-16
FR2344523A1 (en) 1977-10-14
BE852359A (en) 1977-09-12
FR2344523B1 (en) 1981-01-09
NL7702560A (en) 1977-09-13
PH14145A (en) 1981-03-05
IL51644A (en) 1981-02-27
GB1545291A (en) 1979-05-10
JPS5831336B2 (en) 1983-07-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009