ES466892A1 - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- ES466892A1 ES466892A1 ES466892A ES466892A ES466892A1 ES 466892 A1 ES466892 A1 ES 466892A1 ES 466892 A ES466892 A ES 466892A ES 466892 A ES466892 A ES 466892A ES 466892 A1 ES466892 A1 ES 466892A1
- Authority
- ES
- Spain
- Prior art keywords
- adsorbate
- composition
- water
- pharmacologically acceptable
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
A pharmacologically acceptable bile acid sequestering agent composition which after the prolonged action of moist air does not stick and is free-flowing, contains an essentially uniform adsorbate of a quaternary ionic polymer on a finely divided, water-insoluble, solid, pharmacologically acceptable aggregate having a large surface-to-mass ratio. The composition is prepared by mixing the component in aqueous solution, evaporating the water and drying the adsorbate thus formed. The composition described can be used for the reduction of cholesterol in the blood.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76949177A | 1977-02-17 | 1977-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466892A1 true ES466892A1 (en) | 1979-08-16 |
Family
ID=25085598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466892A Expired ES466892A1 (en) | 1977-02-17 | 1978-02-10 | Pharmaceutical compositions |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS53102958A (en) |
| AT (1) | AT363173B (en) |
| AU (1) | AU518127B2 (en) |
| BE (1) | BE863930A (en) |
| CA (1) | CA1109395A (en) |
| CH (1) | CH636012A5 (en) |
| DE (1) | DE2806707A1 (en) |
| DK (1) | DK46578A (en) |
| ES (1) | ES466892A1 (en) |
| FI (1) | FI67483C (en) |
| FR (1) | FR2381079A1 (en) |
| GB (1) | GB1567294A (en) |
| GR (1) | GR66100B (en) |
| HU (1) | HU177685B (en) |
| IE (1) | IE46408B1 (en) |
| IL (1) | IL53978A (en) |
| IT (1) | IT7848013A0 (en) |
| LU (1) | LU79071A1 (en) |
| NL (1) | NL7801240A (en) |
| NO (1) | NO148838C (en) |
| NZ (1) | NZ186399A (en) |
| PH (1) | PH15263A (en) |
| PL (1) | PL122299B1 (en) |
| PT (1) | PT67663B (en) |
| SE (1) | SE433170B (en) |
| ZA (1) | ZA78913B (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5624963A (en) * | 1993-06-02 | 1997-04-29 | Geltex Pharmaceuticals, Inc. | Process for removing bile salts from a patient and compositions therefor |
| US5607669A (en) * | 1994-06-10 | 1997-03-04 | Geltex Pharmaceuticals, Inc. | Amine polymer sequestrant and method of cholesterol depletion |
| US5929184A (en) * | 1993-06-02 | 1999-07-27 | Geltex Pharmaceuticals, Inc. | Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants |
| US5703188A (en) * | 1993-06-02 | 1997-12-30 | Geltex Pharmaceuticals, Inc. | Process for removing bile salts from a patient and compositions therefor |
| US5900475A (en) * | 1994-06-10 | 1999-05-04 | Geltex Pharmaceuticals, Inc. | Hydrophobic sequestrant for cholesterol depletion |
| US5618530A (en) * | 1994-06-10 | 1997-04-08 | Geltex Pharmaceuticals, Inc. | Hydrophobic amine polymer sequestrant and method of cholesterol depletion |
| US6129910A (en) * | 1993-06-02 | 2000-10-10 | Geltex Pharmaceuticals, Inc. | Water-insoluble noncrosslinked bile acid sequestrants |
| TW474813B (en) | 1994-06-10 | 2002-02-01 | Geltex Pharma Inc | Alkylated composition for removing bile salts from a patient |
| US5709880A (en) * | 1995-07-10 | 1998-01-20 | Buckman Laboratories International, Inc. | Method of making tabletized ionene polymers |
| EP0778027A3 (en) | 1995-12-04 | 1998-04-01 | Helmut Univ.-Prof. Dr. Wachter | Use of silica for the preparation of a medicament |
| JP4010585B2 (en) * | 1996-10-15 | 2007-11-21 | 久光製薬株式会社 | Tablets containing anion exchange resin |
| US6203785B1 (en) | 1996-12-30 | 2001-03-20 | Geltex Pharmaceuticals, Inc. | Poly(diallylamine)-based bile acid sequestrants |
| US6423754B1 (en) | 1997-06-18 | 2002-07-23 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with polyallylamine polymers |
| US6726905B1 (en) | 1997-11-05 | 2004-04-27 | Genzyme Corporation | Poly (diallylamines)-based phosphate binders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4027009A (en) * | 1973-06-11 | 1977-05-31 | Merck & Co., Inc. | Compositions and methods for depressing blood serum cholesterol |
| AR206115A1 (en) * | 1973-06-11 | 1976-06-30 | Merck & Co Inc | PROCEDURE TO PREPARE A NON-BRANCHED AND NON-CROSSLINK LINEAR POLYMER |
-
1978
- 1978-01-30 FI FI780296A patent/FI67483C/en not_active IP Right Cessation
- 1978-02-01 DK DK46578A patent/DK46578A/en not_active Application Discontinuation
- 1978-02-02 NO NO780367A patent/NO148838C/en unknown
- 1978-02-02 NL NL7801240A patent/NL7801240A/en not_active Application Discontinuation
- 1978-02-02 SE SE7801242A patent/SE433170B/en unknown
- 1978-02-06 IL IL53978A patent/IL53978A/en unknown
- 1978-02-06 PH PH20753A patent/PH15263A/en unknown
- 1978-02-06 GR GR55356A patent/GR66100B/el unknown
- 1978-02-07 NZ NZ186399A patent/NZ186399A/en unknown
- 1978-02-08 AT AT0087978A patent/AT363173B/en not_active IP Right Cessation
- 1978-02-08 CA CA296,622A patent/CA1109395A/en not_active Expired
- 1978-02-08 AU AU33099/78A patent/AU518127B2/en not_active Expired
- 1978-02-09 HU HU78ME2145A patent/HU177685B/en unknown
- 1978-02-10 IT IT7848013A patent/IT7848013A0/en unknown
- 1978-02-10 ES ES466892A patent/ES466892A1/en not_active Expired
- 1978-02-14 CH CH162578A patent/CH636012A5/en not_active IP Right Cessation
- 1978-02-14 BE BE185141A patent/BE863930A/en not_active IP Right Cessation
- 1978-02-15 FR FR7804268A patent/FR2381079A1/en active Granted
- 1978-02-15 PL PL1978204642A patent/PL122299B1/en unknown
- 1978-02-15 LU LU79071A patent/LU79071A1/en unknown
- 1978-02-15 GB GB6014/78A patent/GB1567294A/en not_active Expired
- 1978-02-16 IE IE332/78A patent/IE46408B1/en unknown
- 1978-02-16 ZA ZA00780913A patent/ZA78913B/en unknown
- 1978-02-16 PT PT67663A patent/PT67663B/en unknown
- 1978-02-16 DE DE19782806707 patent/DE2806707A1/en not_active Withdrawn
- 1978-02-17 JP JP1666278A patent/JPS53102958A/en active Pending
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |