ES466054A1 - Procedimiento de preparacion de compuestos del acido amino- espiro(oxa(o tia)cicloalcano-penam)-carboxilico - Google Patents
Procedimiento de preparacion de compuestos del acido amino- espiro(oxa(o tia)cicloalcano-penam)-carboxilicoInfo
- Publication number
- ES466054A1 ES466054A1 ES466054A ES466054A ES466054A1 ES 466054 A1 ES466054 A1 ES 466054A1 ES 466054 A ES466054 A ES 466054A ES 466054 A ES466054 A ES 466054A ES 466054 A1 ES466054 A1 ES 466054A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- penam
- thia
- cycloalkane
- oxa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000534944 Thia Species 0.000 title abstract 2
- -1 2-phenylacetyl Chemical group 0.000 abstract 5
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000475 sulfinyl group Chemical group [*:2]S([*:1])=O 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
- B60W2510/00—Input parameters relating to a particular sub-units
- B60W2510/02—Clutches
- B60W2510/0208—Clutch engagement state, e.g. engaged or disengaged
- B60W2510/0225—Clutch actuator position
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
- B60W2510/00—Input parameters relating to a particular sub-units
- B60W2510/02—Clutches
- B60W2510/0241—Clutch slip, i.e. difference between input and output speeds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
- B60W2510/00—Input parameters relating to a particular sub-units
- B60W2510/06—Combustion engines, Gas turbines
- B60W2510/0638—Engine speed
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
- B60W2710/00—Output or target parameters relating to a particular sub-units
- B60W2710/02—Clutches
- B60W2710/025—Clutch slip, i.e. difference between input and output speeds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60W—CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT
- B60W2710/00—Output or target parameters relating to a particular sub-units
- B60W2710/02—Clutches
- B60W2710/027—Clutch torque
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedimiento de preparación de nuevos derivados del ácido amino-espiro[oxa(o tia)cicloalcano-penam]-carboxílico que responden a la fórmula: **(Fórmula)** en la que x representa un átomo de azufre o de oxígeno o el grupo sulfinilo, n y m son independientemente uno del otro los números enteros 1 o 2, preferiblemente 2; R1 representa hidrógeno y R2 representa un radical elegido entre los radicales conocidos en la química de las penicilinas, preferiblemente un radical elegido entre los radicales 2-fenilacetilo, 2-amino-2-fenilacetilo, 5-metil-3-fenil-4-isoxazolcarbonilo y 2,6-dimetoxi-benzoilo, sus sales tóxidas farmacéuticamente aceptables, preferiblemente las sales de sodio y potasio.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1906/77A GB1567562A (en) | 1977-01-18 | 1977-01-18 | Amino-spiro(oxy(or thia) cycloalkane - penam) - carboxylicacid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466054A1 true ES466054A1 (es) | 1979-01-01 |
Family
ID=9730122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466054A Expired ES466054A1 (es) | 1977-01-18 | 1978-01-17 | Procedimiento de preparacion de compuestos del acido amino- espiro(oxa(o tia)cicloalcano-penam)-carboxilico |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4139628A (es) |
| JP (1) | JPS5390291A (es) |
| AT (1) | AT355209B (es) |
| AU (1) | AU512339B2 (es) |
| BE (1) | BE862973A (es) |
| CA (1) | CA1101841A (es) |
| CH (1) | CH629812A5 (es) |
| DD (1) | DD134525A5 (es) |
| DE (1) | DE2801850A1 (es) |
| DK (1) | DK15778A (es) |
| ES (1) | ES466054A1 (es) |
| FI (1) | FI780089A (es) |
| FR (1) | FR2377409A1 (es) |
| GB (1) | GB1567562A (es) |
| HU (1) | HU173787B (es) |
| IL (1) | IL53826A (es) |
| IT (1) | IT1103253B (es) |
| LU (1) | LU78884A1 (es) |
| NL (1) | NL7800395A (es) |
| NO (1) | NO780111L (es) |
| PL (1) | PL204065A1 (es) |
| PT (1) | PT67538B (es) |
| SE (1) | SE7800368L (es) |
| SU (1) | SU791245A3 (es) |
| YU (1) | YU8678A (es) |
| ZA (1) | ZA78305B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2052496B (en) * | 1979-06-25 | 1983-06-29 | Ucb Sa | 6 - amino - spiro - (penam - 2,4' - piperidine) - 3 - carboxylic acid derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2951839A (en) * | 1959-07-15 | 1960-09-06 | Doyle Frank Peter | Synthetic penicillins |
-
1977
- 1977-01-18 GB GB1906/77A patent/GB1567562A/en not_active Expired
-
1978
- 1978-01-12 SE SE7800368A patent/SE7800368L/xx unknown
- 1978-01-12 NL NL7800395A patent/NL7800395A/xx not_active Application Discontinuation
- 1978-01-12 DK DK15778A patent/DK15778A/da not_active Application Discontinuation
- 1978-01-12 FI FI780089A patent/FI780089A/fi not_active Application Discontinuation
- 1978-01-12 NO NO780111A patent/NO780111L/no unknown
- 1978-01-16 US US05/869,860 patent/US4139628A/en not_active Expired - Lifetime
- 1978-01-17 CA CA295,138A patent/CA1101841A/en not_active Expired
- 1978-01-17 CH CH44978A patent/CH629812A5/fr not_active IP Right Cessation
- 1978-01-17 DE DE19782801850 patent/DE2801850A1/de not_active Withdrawn
- 1978-01-17 IL IL53826A patent/IL53826A/xx unknown
- 1978-01-17 BE BE1008647A patent/BE862973A/xx not_active IP Right Cessation
- 1978-01-17 AU AU32496/78A patent/AU512339B2/en not_active Expired
- 1978-01-17 PT PT67538A patent/PT67538B/pt unknown
- 1978-01-17 ZA ZA00780305A patent/ZA78305B/xx unknown
- 1978-01-17 JP JP366778A patent/JPS5390291A/ja active Pending
- 1978-01-17 HU HU78UE85A patent/HU173787B/hu unknown
- 1978-01-17 LU LU78884A patent/LU78884A1/xx unknown
- 1978-01-17 AT AT32278A patent/AT355209B/de not_active IP Right Cessation
- 1978-01-17 IT IT47659/78A patent/IT1103253B/it active
- 1978-01-17 YU YU00086/78A patent/YU8678A/xx unknown
- 1978-01-17 FR FR7801579A patent/FR2377409A1/fr active Granted
- 1978-01-17 DD DD78203262A patent/DD134525A5/xx unknown
- 1978-01-17 ES ES466054A patent/ES466054A1/es not_active Expired
- 1978-01-18 PL PL20406578A patent/PL204065A1/xx unknown
- 1978-01-18 SU SU782566099A patent/SU791245A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| IL53826A0 (en) | 1978-04-30 |
| FI780089A (fi) | 1978-07-19 |
| SU791245A3 (ru) | 1980-12-23 |
| DD134525A5 (de) | 1979-03-07 |
| DK15778A (da) | 1978-07-19 |
| FR2377409A1 (fr) | 1978-08-11 |
| IT7847659A0 (it) | 1978-01-17 |
| NL7800395A (nl) | 1978-07-20 |
| ZA78305B (en) | 1978-12-27 |
| CH629812A5 (fr) | 1982-05-14 |
| GB1567562A (en) | 1980-05-14 |
| LU78884A1 (fr) | 1978-09-18 |
| AT355209B (de) | 1980-02-25 |
| AU3249678A (en) | 1979-07-26 |
| JPS5390291A (en) | 1978-08-08 |
| ATA32278A (de) | 1979-07-15 |
| PL204065A1 (pl) | 1979-04-09 |
| YU8678A (en) | 1983-01-21 |
| BE862973A (fr) | 1978-07-17 |
| CA1101841A (en) | 1981-05-26 |
| NO780111L (no) | 1978-07-19 |
| DE2801850A1 (de) | 1978-07-20 |
| US4139628A (en) | 1979-02-13 |
| HU173787B (hu) | 1979-08-28 |
| IT1103253B (it) | 1985-10-14 |
| PT67538A (fr) | 1978-02-01 |
| IL53826A (en) | 1981-01-30 |
| FR2377409B1 (es) | 1980-06-13 |
| PT67538B (fr) | 1979-06-15 |
| SE7800368L (sv) | 1978-07-19 |
| AU512339B2 (en) | 1980-10-02 |
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