ES465758A1 - Procedimiento de obtencion del monoester del acido p-cloro- fenoxi-isobutirico con 2,6-piridindimetanol, nuevo farmaco con accion hipocolesteremiante. - Google Patents
Procedimiento de obtencion del monoester del acido p-cloro- fenoxi-isobutirico con 2,6-piridindimetanol, nuevo farmaco con accion hipocolesteremiante.Info
- Publication number
- ES465758A1 ES465758A1 ES465758A ES465758A ES465758A1 ES 465758 A1 ES465758 A1 ES 465758A1 ES 465758 A ES465758 A ES 465758A ES 465758 A ES465758 A ES 465758A ES 465758 A1 ES465758 A1 ES 465758A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- chlorophenoxy
- pyridindimethanol
- isobutirico
- hypocolesteramient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WWFMINHWJYHXHF-UHFFFAOYSA-N [6-(hydroxymethyl)pyridin-2-yl]methanol Chemical compound OCC1=CC=CC(CO)=N1 WWFMINHWJYHXHF-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- TXCGAZHTZHNUAI-UHFFFAOYSA-N clofibric acid Chemical class OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 TXCGAZHTZHNUAI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicinal Preparation (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES465758A ES465758A1 (es) | 1978-01-04 | 1978-01-04 | Procedimiento de obtencion del monoester del acido p-cloro- fenoxi-isobutirico con 2,6-piridindimetanol, nuevo farmaco con accion hipocolesteremiante. |
| FR7835595A FR2414041A1 (fr) | 1978-01-04 | 1978-12-18 | 2-(a-(p-chlorophenoxy) isobutyrate) de 2,6-pyridinedimethanol, applications therapeutiques et procede de preparation |
| GR57923A GR69617B (en, 2012) | 1978-01-04 | 1978-12-18 | |
| DE19782855811 DE2855811A1 (de) | 1978-01-04 | 1978-12-22 | 2- eckige klammer auf alpha -(p- chlorphenoxy)isobutyrat eckige klammer zu von 2,6-pyridindimethanol, verfahren zu seiner herstellung und es enthaltendes arzneimittel |
| PH21998A PH14894A (en) | 1978-01-04 | 1978-12-28 | 2,6-pyridinedimethanol 2(alpha-(p-chlorophenoxy)isobutyric)acid ester,preparation and therapeutical use thereof |
| LU80750A LU80750A1 (fr) | 1978-01-04 | 1979-01-02 | 2-((p-chlorophenoxy)isobutyrate)de 2,6-pyridinedimethanol,applications therapeutiques et procede de preparation |
| CA318,930A CA1114383A (en) | 1978-01-04 | 1979-01-02 | 2,6-pyridinedimethanol 2-¬a-(p-chlorophenoxy)- isobutyric acid| |
| IT67006/79A IT1118259B (it) | 1978-01-04 | 1979-01-03 | Derivato del 2 6 piridinometanolo particolarmente utile in terapia e procedimento per la sua preparazione |
| MX797611U MX5621E (es) | 1978-01-04 | 1979-01-03 | Procedimiento para preparar el monoester 2-(p-cloro-fenoxi-isobutirato)-2,6-piridin-dimetanol |
| CH2979A CH639072A5 (en) | 1978-01-04 | 1979-01-03 | 2-[ alpha -(p-Chlorophenoxy)isobutyrate] of 2,6-pyridinedimethanol and process for its preparation |
| PT69024A PT69024A (fr) | 1978-01-04 | 1979-01-03 | Procede d'obtention du monoester d'acide p-chlorophenoxi-isobutyrique du 2,6-pyridinedimethanol |
| BR7900022A BR7900022A (pt) | 1978-01-04 | 1979-01-03 | 2-(a(p-clorofenoxi)isobutirato)de 2,6-piridinadimetanol,aplicacoes terapeuticas e processo de preparacao |
| BE2/57529A BE873280A (fr) | 1978-01-04 | 1979-01-03 | 2-beta-(p-chlorophenoxy)isobutyrate) de 2,6-pyridinedimethanol, applications therapeutiques et procede de preparation |
| AT0006179A AT369360B (de) | 1978-01-04 | 1979-01-04 | Verfahren zur herstellung des monoesters von 2(p-chlorphenoxy)-isobuttersaeure mit 2,6-pyridindimethanol sowie von dessen salzen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES465758A ES465758A1 (es) | 1978-01-04 | 1978-01-04 | Procedimiento de obtencion del monoester del acido p-cloro- fenoxi-isobutirico con 2,6-piridindimetanol, nuevo farmaco con accion hipocolesteremiante. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES465758A1 true ES465758A1 (es) | 1978-11-16 |
Family
ID=8475233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES465758A Expired ES465758A1 (es) | 1978-01-04 | 1978-01-04 | Procedimiento de obtencion del monoester del acido p-cloro- fenoxi-isobutirico con 2,6-piridindimetanol, nuevo farmaco con accion hipocolesteremiante. |
Country Status (14)
| Country | Link |
|---|---|
| AT (1) | AT369360B (en, 2012) |
| BE (1) | BE873280A (en, 2012) |
| BR (1) | BR7900022A (en, 2012) |
| CA (1) | CA1114383A (en, 2012) |
| CH (1) | CH639072A5 (en, 2012) |
| DE (1) | DE2855811A1 (en, 2012) |
| ES (1) | ES465758A1 (en, 2012) |
| FR (1) | FR2414041A1 (en, 2012) |
| GR (1) | GR69617B (en, 2012) |
| IT (1) | IT1118259B (en, 2012) |
| LU (1) | LU80750A1 (en, 2012) |
| MX (1) | MX5621E (en, 2012) |
| PH (1) | PH14894A (en, 2012) |
| PT (1) | PT69024A (en, 2012) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2214511A1 (en) * | 1973-01-19 | 1974-08-19 | Perreau Louis | Suspension of increased storage stability - prepd. by freezing and then thawing of a solid in a liquid |
-
1978
- 1978-01-04 ES ES465758A patent/ES465758A1/es not_active Expired
- 1978-12-18 GR GR57923A patent/GR69617B/el unknown
- 1978-12-18 FR FR7835595A patent/FR2414041A1/fr active Granted
- 1978-12-22 DE DE19782855811 patent/DE2855811A1/de not_active Withdrawn
- 1978-12-28 PH PH21998A patent/PH14894A/en unknown
-
1979
- 1979-01-02 CA CA318,930A patent/CA1114383A/en not_active Expired
- 1979-01-02 LU LU80750A patent/LU80750A1/xx unknown
- 1979-01-03 MX MX797611U patent/MX5621E/es unknown
- 1979-01-03 BE BE2/57529A patent/BE873280A/xx not_active IP Right Cessation
- 1979-01-03 IT IT67006/79A patent/IT1118259B/it active
- 1979-01-03 CH CH2979A patent/CH639072A5/fr not_active IP Right Cessation
- 1979-01-03 BR BR7900022A patent/BR7900022A/pt unknown
- 1979-01-03 PT PT69024A patent/PT69024A/pt unknown
- 1979-01-04 AT AT0006179A patent/AT369360B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2414041A1 (fr) | 1979-08-03 |
| PH14894A (en) | 1982-01-08 |
| GR69617B (en, 2012) | 1982-07-06 |
| CH639072A5 (en) | 1983-10-31 |
| BE873280A (fr) | 1979-07-03 |
| DE2855811A1 (de) | 1979-07-05 |
| BR7900022A (pt) | 1979-08-07 |
| ATA6179A (de) | 1982-05-15 |
| AT369360B (de) | 1982-12-27 |
| FR2414041B1 (en, 2012) | 1981-07-24 |
| PT69024A (fr) | 1979-02-01 |
| LU80750A1 (fr) | 1979-04-13 |
| CA1114383A (en) | 1981-12-15 |
| IT1118259B (it) | 1986-02-24 |
| IT7967006A0 (it) | 1979-01-03 |
| MX5621E (es) | 1983-11-09 |
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