ES465758A1 - Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES465758A1
ES465758A1 ES465758A ES465758A ES465758A1 ES 465758 A1 ES465758 A1 ES 465758A1 ES 465758 A ES465758 A ES 465758A ES 465758 A ES465758 A ES 465758A ES 465758 A1 ES465758 A1 ES 465758A1
Authority
ES
Spain
Prior art keywords
acid
chlorophenoxy
pyridindimethanol
isobutirico
hypocolesteramient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465758A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Especialidades Latinas Medicamentos Universales SA
Original Assignee
Especialidades Latinas Medicamentos Universales SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES465758A priority Critical patent/ES465758A1/en
Application filed by Especialidades Latinas Medicamentos Universales SA filed Critical Especialidades Latinas Medicamentos Universales SA
Publication of ES465758A1 publication Critical patent/ES465758A1/en
Priority to GR57923A priority patent/GR69617B/el
Priority to FR7835595A priority patent/FR2414041A1/en
Priority to DE19782855811 priority patent/DE2855811A1/en
Priority to PH21998A priority patent/PH14894A/en
Priority to CA318,930A priority patent/CA1114383A/en
Priority to LU80750A priority patent/LU80750A1/en
Priority to BE2/57529A priority patent/BE873280A/en
Priority to CH2979A priority patent/CH639072A5/en
Priority to IT67006/79A priority patent/IT1118259B/en
Priority to BR7900022A priority patent/BR7900022A/en
Priority to PT69024A priority patent/PT69024A/en
Priority to MX797611U priority patent/MX5621E/en
Priority to AT0006179A priority patent/AT369360B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

2-[ alpha -(p-Chlorophenoxy)isobutyrate] of 2,6-pyridinedimethanol of expanded formula < IMAGE > and its pharmaceutically acceptable salts, as well as its process of preparation, are described. In order to prepare this compound, alpha -(p-chlorophenoxy)isobutyric acid and 2,6-pyridinemethanol are reacted in equimolar amounts in the presence of an acid catalyst, preferably a sulphonic acid or sulphuric acid, in a water-immiscible medium, preferably xylene or toluene. Applications: treatment of lipid metabolism disorders.
ES465758A 1978-01-04 1978-01-04 Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding) Expired ES465758A1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
ES465758A ES465758A1 (en) 1978-01-04 1978-01-04 Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding)
GR57923A GR69617B (en) 1978-01-04 1978-12-18
FR7835595A FR2414041A1 (en) 1978-01-04 1978-12-18 2- (A- (P-CHLOROPHENOXY) ISOBUTYRATE) 2,6-PYRIDINEDIMETHANOL, THERAPEUTIC APPLICATIONS AND METHOD OF PREPARATION
DE19782855811 DE2855811A1 (en) 1978-01-04 1978-12-22 2- SQUARE BRACKET ON ALPHA -(P-CHLORPHENOXY)ISOBUTYRATE SQUARE BRACKET ON 2,6-PYRIDINE DIMETHANOL, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCT CONTAINING IT
PH21998A PH14894A (en) 1978-01-04 1978-12-28 2,6-pyridinedimethanol 2(alpha-(p-chlorophenoxy)isobutyric)acid ester,preparation and therapeutical use thereof
CA318,930A CA1114383A (en) 1978-01-04 1979-01-02 2,6-pyridinedimethanol 2-¬a-(p-chlorophenoxy)- isobutyric acid|
LU80750A LU80750A1 (en) 1978-01-04 1979-01-02 2 - 2,6-PYRIDINEDIMETHANOL ((P-CHLOROPHENOXY) ISOBUTYRATE), THERAPEUTIC APPLICATIONS AND METHOD OF PREPARATION
BE2/57529A BE873280A (en) 1978-01-04 1979-01-03 2,6-PYRIDINEDIMETHANOL 2-BETA- (P-CHLOROPHENOXY) ISOBUTYRATE), THERAPEUTIC APPLICATIONS AND METHOD OF PREPARATION
MX797611U MX5621E (en) 1978-01-04 1979-01-03 PROCEDURE FOR PREPARING MONOSTER 2- (P-CHLORINE-PHENOXY-ISOBUTYRATE) -2,6-PIRIDIN-DIMETHANOL
CH2979A CH639072A5 (en) 1978-01-04 1979-01-03 2-[ alpha -(p-Chlorophenoxy)isobutyrate] of 2,6-pyridinedimethanol and process for its preparation
IT67006/79A IT1118259B (en) 1978-01-04 1979-01-03 DERIVATIVE OF 2 6 PYRIDOMETHANOL PARTICULARLY USEFUL IN THERAPY AND PROCEDURE FOR ITS PREPARATION
BR7900022A BR7900022A (en) 1978-01-04 1979-01-03 2- (A (P-CHLOROPHENOXI) ISOBUTIRATE) 2,6-PYRIDINADIMETHANOL, THERAPEUTIC APPLICATIONS AND PREPARATION PROCESS
PT69024A PT69024A (en) 1978-01-04 1979-01-03 PROCESS FOR OBTAINING MONOESTER OF P-CHLOROPHENOXI-ISOBUTYRIC 2,6-PYRIDINEDIMETHANOL ACID
AT0006179A AT369360B (en) 1978-01-04 1979-01-04 METHOD FOR PRODUCING THE MONOESTER OF 2 (P-CHLORPHENOXY) ISOBUTTERIC ACID WITH 2,6-PYRIDINE DIMETHANOL AND ITS SALTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES465758A ES465758A1 (en) 1978-01-04 1978-01-04 Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES465758A1 true ES465758A1 (en) 1978-11-16

Family

ID=8475233

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465758A Expired ES465758A1 (en) 1978-01-04 1978-01-04 Procedure for obtaining monoester from p-chlorophenoxy-isobutirico acid with 2,6-pyridindimethanol, new pharmacy with hypocolesteramient action. (Machine-translation by Google Translate, not legally binding)

Country Status (14)

Country Link
AT (1) AT369360B (en)
BE (1) BE873280A (en)
BR (1) BR7900022A (en)
CA (1) CA1114383A (en)
CH (1) CH639072A5 (en)
DE (1) DE2855811A1 (en)
ES (1) ES465758A1 (en)
FR (1) FR2414041A1 (en)
GR (1) GR69617B (en)
IT (1) IT1118259B (en)
LU (1) LU80750A1 (en)
MX (1) MX5621E (en)
PH (1) PH14894A (en)
PT (1) PT69024A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2214511A1 (en) * 1973-01-19 1974-08-19 Perreau Louis Suspension of increased storage stability - prepd. by freezing and then thawing of a solid in a liquid

Also Published As

Publication number Publication date
IT7967006A0 (en) 1979-01-03
DE2855811A1 (en) 1979-07-05
BE873280A (en) 1979-07-03
GR69617B (en) 1982-07-06
BR7900022A (en) 1979-08-07
LU80750A1 (en) 1979-04-13
AT369360B (en) 1982-12-27
FR2414041B1 (en) 1981-07-24
PH14894A (en) 1982-01-08
ATA6179A (en) 1982-05-15
IT1118259B (en) 1986-02-24
CH639072A5 (en) 1983-10-31
FR2414041A1 (en) 1979-08-03
CA1114383A (en) 1981-12-15
MX5621E (en) 1983-11-09
PT69024A (en) 1979-02-01

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