ES464941A1 - Un procedimiento para la preparacion de nuevos eteres de acido clavulanico - Google Patents
Un procedimiento para la preparacion de nuevos eteres de acido clavulanicoInfo
- Publication number
- ES464941A1 ES464941A1 ES464941A ES464941A ES464941A1 ES 464941 A1 ES464941 A1 ES 464941A1 ES 464941 A ES464941 A ES 464941A ES 464941 A ES464941 A ES 464941A ES 464941 A1 ES464941 A1 ES 464941A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- formula
- salts
- carboxylic esters
- carboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedimiento para la preparación de nuevos éteres de ácido clavulánico de fórmula (I) **fórmula** o una sal o éster del mismo, donde R es un grupo metilo o etilo, que consiste en hacer reaccionar ácido clavulánico o una sal o éster del mismo con una sal de oxonio de fórmula II R3O+.X- (II) donde R3 es un grupo metilo o etilo y X- es un anión opcionalmente, en presencia de una base y después, si se desea, llevar a cabo una de las dos reacciones siguientes o ambas: (a) convertir el éster así formado en el ácido o en una sal y (b) convertir el ácido o la sal así formado en otro éster o en otra sal.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB51808/76A GB1589367A (en) | 1976-12-11 | 1976-12-11 | Clavulanic acid ethers |
| GB1111677 | 1977-03-16 | ||
| GB3875377 | 1977-09-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES464941A1 true ES464941A1 (es) | 1979-12-16 |
Family
ID=27256638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES464941A Expired ES464941A1 (es) | 1976-12-11 | 1977-12-09 | Un procedimiento para la preparacion de nuevos eteres de acido clavulanico |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5377090A (es) |
| AR (1) | AR216117A1 (es) |
| AT (1) | AT356269B (es) |
| CA (1) | CA1097653A (es) |
| CH (1) | CH636880A5 (es) |
| DE (1) | DE2754763A1 (es) |
| ES (1) | ES464941A1 (es) |
| FR (1) | FR2373545A1 (es) |
| GR (1) | GR64001B (es) |
| IE (1) | IE46436B1 (es) |
| IL (1) | IL53465A (es) |
| MX (1) | MX4846E (es) |
| NL (1) | NL7713644A (es) |
| NZ (1) | NZ185849A (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2862254D1 (en) * | 1977-12-02 | 1983-06-16 | Beecham Group Plc | A process for the preparation of ether derivatives of clavulanic acid |
| DE3062347D1 (en) * | 1979-08-11 | 1983-04-21 | Beecham Group Plc | Process for the preparation of derivatives of clavulanic acid |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1573503A (en) * | 1975-12-17 | 1980-08-28 | Glaxo Lab Ltd | Clavulanic acid derivatives |
-
1977
- 1977-11-25 IL IL53465A patent/IL53465A/xx unknown
- 1977-12-05 NZ NZ185849A patent/NZ185849A/xx unknown
- 1977-12-07 FR FR7736817A patent/FR2373545A1/fr active Granted
- 1977-12-08 DE DE19772754763 patent/DE2754763A1/de not_active Withdrawn
- 1977-12-09 MX MX776680U patent/MX4846E/es unknown
- 1977-12-09 AT AT881677A patent/AT356269B/de not_active IP Right Cessation
- 1977-12-09 ES ES464941A patent/ES464941A1/es not_active Expired
- 1977-12-09 AR AR270306A patent/AR216117A1/es active
- 1977-12-09 GR GR54946A patent/GR64001B/el unknown
- 1977-12-09 NL NL7713644A patent/NL7713644A/xx not_active Application Discontinuation
- 1977-12-09 CA CA292,807A patent/CA1097653A/en not_active Expired
- 1977-12-09 JP JP14865677A patent/JPS5377090A/ja active Pending
- 1977-12-09 IE IE2501/77A patent/IE46436B1/en unknown
- 1977-12-12 CH CH1523577A patent/CH636880A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AR216117A1 (es) | 1979-11-30 |
| NL7713644A (nl) | 1978-06-13 |
| ATA881677A (de) | 1979-09-15 |
| CH636880A5 (en) | 1983-06-30 |
| MX4846E (es) | 1982-10-28 |
| CA1097653A (en) | 1981-03-17 |
| GR64001B (en) | 1980-01-18 |
| IE772501L (en) | 1978-06-11 |
| AT356269B (de) | 1980-04-25 |
| FR2373545A1 (fr) | 1978-07-07 |
| FR2373545B1 (es) | 1982-04-16 |
| NZ185849A (en) | 1980-11-28 |
| IL53465A (en) | 1980-11-30 |
| IL53465A0 (en) | 1978-01-31 |
| JPS5377090A (en) | 1978-07-08 |
| DE2754763A1 (de) | 1978-06-15 |
| IE46436B1 (en) | 1983-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19841217 |