ES8104323A1 - Un procedimiento para obtener 2,6-diaminonebularinas - Google Patents

Un procedimiento para obtener 2,6-diaminonebularinas

Info

Publication number
ES8104323A1
ES8104323A1 ES490101A ES490101A ES8104323A1 ES 8104323 A1 ES8104323 A1 ES 8104323A1 ES 490101 A ES490101 A ES 490101A ES 490101 A ES490101 A ES 490101A ES 8104323 A1 ES8104323 A1 ES 8104323A1
Authority
ES
Spain
Prior art keywords
formula
image
compound
amino
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490101A
Other languages
English (en)
Other versions
ES490101A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES8104323A1 publication Critical patent/ES8104323A1/es
Publication of ES490101A0 publication Critical patent/ES490101A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER 2,6-DIAMINONEBULARINAS, DE FORMULA (I), EN DONDE R ES FENILO, QUE PUEDE ESTAR SUSTITUIDO; O SU SAL DE ADICION DE ACIDO. COMPRENDE HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA *FORMULA*; R ELEVADO A 1, R ELEVADO A 2 Y R ELEVADO A 3, INDEPENDIENTEMENTE UNO DE OTRO, SON HIDROXILO; X ES AMINO QUE PUEDE ESTAR SUSTITUIDO, O ALCOHILO INFERIOR. ESTOS COMPUESTOS TIENEN ACCION SOBRE LA CORONARIA COMO VASODILATADORES Y COMO INHIBIDORES DE LA AGRUPACION DE PLAQUETAS. *FORMULA* T
ES490101A 1979-04-02 1980-03-31 Un procedimiento para obtener 2,6-diaminonebularinas Granted ES490101A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3956279A JPS55130998A (en) 1979-04-02 1979-04-02 N2-substituted 2,6-diaminonebularin

Publications (2)

Publication Number Publication Date
ES8104323A1 true ES8104323A1 (es) 1981-04-01
ES490101A0 ES490101A0 (es) 1981-04-01

Family

ID=12556512

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490101A Granted ES490101A0 (es) 1979-04-02 1980-03-31 Un procedimiento para obtener 2,6-diaminonebularinas

Country Status (12)

Country Link
US (1) US4293690A (es)
EP (1) EP0017465A1 (es)
JP (1) JPS55130998A (es)
AU (1) AU5698280A (es)
DK (1) DK134580A (es)
ES (1) ES490101A0 (es)
FI (1) FI801033A (es)
GR (1) GR67615B (es)
IL (1) IL59602A0 (es)
NO (1) NO800868L (es)
NZ (1) NZ193324A (es)
PH (1) PH15849A (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56152437U (es) * 1980-04-14 1981-11-14
JPS60193997A (ja) * 1984-03-14 1985-10-02 Sumitomo Chem Co Ltd 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
EP0604409B1 (en) * 1990-01-11 2004-07-14 Isis Pharmaceuticals, Inc. Oligonucleotide analogs for detecting and modulating rna activity and gene expression
US6262241B1 (en) 1990-08-13 2001-07-17 Isis Pharmaceuticals, Inc. Compound for detecting and modulating RNA activity and gene expression
DE19718065A1 (de) * 1997-04-29 1998-11-05 Henkel Kgaa Reinigungsmittel für nachvernetzende Polyurethan-Hotmelts
ES2192495B1 (es) * 2002-03-21 2005-02-16 Universidad De Barcelona Nuevo uso terapeutico del ribosido de 5-aminoimidazol-4-carboxamida (acadesina).
US7956219B2 (en) * 2002-05-09 2011-06-07 Baker IDI Heart and Diabetes Amino acid analogues
CN1972945A (zh) * 2004-04-02 2007-05-30 腺苷治疗有限责任公司 A2a腺苷受体的选择性拮抗剂

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3134778A (en) * 1963-08-20 1964-05-26 Smith Kline French Lab 2,5,7-triamino-4-phenyl (or thienyl)-pyrimido[4,5-d]pyrimidines
FR1535561A (fr) * 1966-06-18 1968-08-09 Ajinomoto Kk Méthode de préparation de l'adénine, de ses dérivés et intermédiaires
US3857842A (en) * 1970-05-06 1974-12-31 Sagami Chem Res Process for preparing purine compounds by reaction of a carbonitrile with formic acid
US3826803A (en) * 1972-02-17 1974-07-30 Icn Pharmaceuticals Arabinofuranosyl-8-azaadenines
DE2359536C2 (de) * 1972-12-08 1984-08-02 Takeda Chemical Industries, Ltd., Osaka 2,6-Diaminonebularinderivate
US4056674A (en) * 1973-07-06 1977-11-01 Icn Pharmaceuticals, Inc. Derivatives of 3-deazaguanine
JPS5461194A (en) * 1977-10-21 1979-05-17 Takeda Chem Ind Ltd Preparation of n22substituted 2*66diaminonebularin

Also Published As

Publication number Publication date
US4293690A (en) 1981-10-06
NZ193324A (en) 1982-09-07
JPS55130998A (en) 1980-10-11
EP0017465A1 (en) 1980-10-15
AU5698280A (en) 1980-10-09
FI801033A (fi) 1980-10-03
IL59602A0 (en) 1980-06-30
DK134580A (da) 1980-10-03
GR67615B (es) 1981-08-31
PH15849A (en) 1983-04-13
NO800868L (no) 1980-10-03
ES490101A0 (es) 1981-04-01

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