ES463207A1 - Un metodo para producir el antibiotico c-15003 - Google Patents

Un metodo para producir el antibiotico c-15003

Info

Publication number
ES463207A1
ES463207A1 ES463207A ES463207A ES463207A1 ES 463207 A1 ES463207 A1 ES 463207A1 ES 463207 A ES463207 A ES 463207A ES 463207 A ES463207 A ES 463207A ES 463207 A1 ES463207 A1 ES 463207A1
Authority
ES
Spain
Prior art keywords
antibiotic
microorganisms
samples
selection
found
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463207A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52037166A external-priority patent/JPS6034556B2/ja
Priority claimed from US05/811,448 external-priority patent/US4162940A/en
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES463207A1 publication Critical patent/ES463207A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Un método para producir el antibiótico C-15003, que tiene la fórmula general: **(Fórmula)** Se han recogido muchas muestras de terreno y otras, y han realizado una selección de los microorganismos aislados de tales muestras. Por dicha selección se halló que algunos de los microorganismos eran capaces de producir un antibiótico nuevo, que tales microorganismos pertenecían al género Nocardia, y que cultivando cualquiera de esos microorganismos en un medio adecuado se podía hacer que dicho antibiótico se acumulase en el caldo de cultivo. También se halló que se podían obtener derivados de dicho antibiótico.
ES463207A 1977-03-31 1977-10-14 Un metodo para producir el antibiotico c-15003 Expired ES463207A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52037166A JPS6034556B2 (ja) 1977-03-31 1977-03-31 抗生物質ｃ−１５００３
US05/811,448 US4162940A (en) 1977-03-31 1977-06-29 Method for producing Antibiotic C-15003 by culturing nocardia

Publications (1)

Publication Number Publication Date
ES463207A1 true ES463207A1 (es) 1979-01-01

Family

ID=26376254

Family Applications (2)

Application Number Title Priority Date Filing Date
ES463207A Expired ES463207A1 (es) 1977-03-31 1977-10-14 Un metodo para producir el antibiotico c-15003
ES472230A Expired ES472230A1 (es) 1977-03-31 1978-07-31 Metodo para producir el antibiotico c-15003 p-o.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES472230A Expired ES472230A1 (es) 1977-03-31 1978-07-31 Metodo para producir el antibiotico c-15003 p-o.

Country Status (16)

Country Link
CA (1) CA1107212A (es)
CS (1) CS214749B2 (es)
DE (1) DE2746209A1 (es)
DK (1) DK458877A (es)
ES (2) ES463207A1 (es)
GB (1) GB1586688A (es)
GR (1) GR66051B (es)
HU (1) HU178359B (es)
IE (1) IE46064B1 (es)
IT (1) IT1094308B (es)
NL (1) NL188102C (es)
PH (2) PH13381A (es)
PL (2) PL122289B1 (es)
PT (1) PT67854B (es)
SE (2) SE442873B (es)
YU (2) YU245377A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562090A (en) * 1978-10-27 1980-05-10 Takeda Chem Ind Ltd Novel maytansinoid compound and its preparation
JPS55102583A (en) * 1979-01-31 1980-08-05 Takeda Chem Ind Ltd 20-acyloxy-20-demethylmaytansinoid compound
JPS5645483A (en) * 1979-09-19 1981-04-25 Takeda Chem Ind Ltd C-15003phm and its preparation
DE19940131B4 (de) * 1998-08-24 2004-12-02 Pfefferle, Christoph, Dr. Verfahren und Vorrichtung zur Gewinnung von biologisch aktiven Substanzen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1336399A (en) * 1971-06-24 1973-11-07 Lepetit Spa 3-formylrifamycin sv derivatives
DE2241418A1 (de) * 1972-08-23 1974-03-07 S Morris Kupchan Antileukaemische ansamakrolide

Also Published As

Publication number Publication date
NL188102B (nl) 1991-11-01
PH13381A (en) 1980-03-25
PH15985A (en) 1983-05-18
IE46064B1 (en) 1983-02-09
PT67854B (en) 1980-05-05
YU245377A (en) 1983-01-21
PL124349B1 (en) 1983-01-31
SE8302517L (sv) 1983-05-03
SE7711542L (sv) 1978-10-01
IT7821818A0 (it) 1978-03-30
NL188102C (nl) 1992-04-01
CS214749B2 (en) 1982-05-28
GR66051B (es) 1981-01-14
NL7711274A (nl) 1978-10-03
IE46064L (en) 1978-09-30
SE8302517D0 (sv) 1983-05-03
DE2746209A1 (de) 1978-10-19
PT67854A (en) 1978-04-01
GB1586688A (en) 1981-03-25
HU178359B (en) 1982-04-28
SE442873B (sv) 1986-02-03
ES472230A1 (es) 1979-04-01
PL122289B1 (en) 1982-07-31
SE446004B (sv) 1986-08-04
PL201541A1 (pl) 1978-10-09
YU178582A (en) 1984-08-31
IT1094308B (it) 1985-07-26
DK458877A (da) 1978-10-01
CA1107212A (en) 1981-08-18
DE2746209C2 (es) 1990-10-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103